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1-BROMO-3-CHLORO-2-IODOBENZENE

1-BROMO-3-CHLORO-2-IODOBENZENE structure

CAS No.: 450412-28-9

Chemical Name:: 1-BROMO-3-CHLORO-2-IODOBENZENE

Synonyms: 2-Bromo-6-chloroiodobenzene;1-BROMO-3-CHLORO-2-IODOBENZENE;2-Bromo-6-chloroiodobenzene 99%;1-Bromo-3-chloro-2-Iodobenzenne;Benzene, 1-bromo-3-chloro-2-iodo-;1-Bromo-3-chloro-2-iodobenzene,97%

CBNumber:: CB62452476

Molecular Formula:: C6H3BrClI

Molecular Weight:: 317.35

MDL Number:: MFCD09907935

MOL File:: 450412-28-9.mol

MSDS File:: SDS

Last updated:2026-05-28 03:59:07

Product description	Number	Pack Size	Price
1-Bromo-3-chloro-2-iodobenzene	B5765	1G	$49
1-Bromo-3-chloro-2-iodobenzene	B5765	5G	$170
2-Bromo-6-chloroiodobenzene 97%	OR400660	5g	$30
2-Bromo-6-chloroiodobenzene 97%	OR400660	25g	$137
1-Bromo-3-chloro-2-iodobenzene 97%	AS113987	5g	$32

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1-BROMO-3-CHLORO-2-IODOBENZENE Properties

Melting point	75-76 °C(Solv: ethanol (64-17-5))
Boiling point	285.9±20.0 °C(Predicted)
Density	2.272±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Solid
Appearance	Off-white to light brown Solid
Sensitive	Light Sensitive
InChI	InChI=1S/C6H3BrClI/c7-4-2-1-3-5(8)6(4)9/h1-3H
InChIKey	GIMVCZMZRZGDTL-UHFFFAOYSA-N
SMILES	C1(Br)=CC=CC(Cl)=C1I

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

HS Code

2903998090

NFPA 704

	1
2		0

1-BROMO-3-CHLORO-2-IODOBENZENE price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B5765	1-Bromo-3-chloro-2-iodobenzene	450412-28-9	1G	$49	2026-04-30	Buy
TCI Chemical	B5765	1-Bromo-3-chloro-2-iodobenzene	450412-28-9	5G	$170	2026-04-30	Buy
Apolloscientific	OR400660	2-Bromo-6-chloroiodobenzene 97%	450412-28-9	5g	$30	2026-06-04	Buy
Apolloscientific	OR400660	2-Bromo-6-chloroiodobenzene 97%	450412-28-9	25g	$137	2026-06-04	Buy
Activate Scientific	AS113987	1-Bromo-3-chloro-2-iodobenzene 97%	450412-28-9	5g	$32	2026-06-04	Buy

Product number	Packaging	Price	Buy
B5765	1G	$49	Buy
B5765	5G	$170	Buy
OR400660	5g	$30	Buy
OR400660	25g	$137	Buy
AS113987	5g	$32	Buy

1-BROMO-3-CHLORO-2-IODOBENZENE Chemical Properties,Uses,Production

Synthesis

108-37-2

450412-28-9

Step 1. Synthesis of 1-bromo-3-chloro-2-iodobenzene: To an anhydrous THF (664 mL) solution containing diisopropylamine (76 mL, 0.4 mol) was slowly added dropwise a n-hexane (220 mL) solution of 2.5 M n-butyllithium (n-BuLi, 160 mL, 0.4 mol) at -78 °C for 1 h under nitrogen protection. The reaction temperature was maintained at -78 °C and stirring was continued for 1 h. A solution of 1-bromo-3-chlorobenzene (76 g, 0.4 mol) in anhydrous THF (300 mL) was added slowly dropwise. After the dropwise addition, the reaction was kept at -78 °C for 1 h. Subsequently, a solution of anhydrous THF (400 mL) with iodine (101 g, 0.4 mol) was added slowly dropwise. The reaction system was gradually warmed to room temperature over 2 hours and stirring was continued at room temperature for 18 hours. After completion of the reaction, the mixture was concentrated under reduced pressure to give the crude product (120 g). The crude product was purified by distillation under reduced pressure to give 1-bromo-3-chloro-2-iodobenzene (115 g, 91% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and mass spectrometry (MS): 1H NMR δ 7.12-7.18 (t, 1H), 7.35-7.41 (dd, 1H), 7.49-7.54 (dd, 1H); MS (E/Z): 317 (M+H+).

References

[1] Patent: WO2008/124575, 2008, A1. Location in patent: Page/Page column 103
[2] Patent: US2010/317697, 2010, A1. Location in patent: Page/Page column 47
[3] Patent: WO2008/124582, 2008, A1. Location in patent: Page/Page column 86-87
[4] Patent: WO2007/117560, 2007, A2. Location in patent: Page/Page column 169
[5] Patent: WO2008/124577, 2008, A1. Location in patent: Page/Page column 69

1-BROMO-3-CHLORO-2-IODOBENZENE Preparation Products And Raw materials

Raw materials

3-BROMOCHLOROBENZENE Tetrahydrofuran Hexane iodine n-Butyllithium

Diisopropylamine

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Preparation Products

1-BROMO-3-CHLORO-2-IODOBENZENE Suppliers

Global( 116)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58
Shanghai Daeyeon Chemicals Co., Ltd	021-64478606 +8615900664856	daeyeon001@vip.163.com	China	2062	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58

Supplier	Advantage
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Richest Group Ltd	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Shanghai Daeyeon Chemicals Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Labnetwork lnc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58

View Lastest Price from 1-BROMO-3-CHLORO-2-IODOBENZENE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-10	1-BROMO-3-CHLORO-2-IODOBENZENE 450412-28-9	$1.00	1g	97%	100kg	Career Henan Chemical Co

1-BROMO-3-CHLORO-2-IODOBENZENE
450412-28-9
$1.00
97%
Career Henan Chemical Co

1-BROMO-3-CHLORO-2-IODOBENZENE Spectrum

1-BROMO-3-CHLORO-2-IODOBENZENE(450412-28-9)¹HNMR 1-BROMO-3-CHLORO-2-IODOBENZENE(450412-28-9)FT-IR

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1-Bromo-3-chloro-2-Iodobenzenne 2-Bromo-6-chloroiodobenzene 99% 1-BROMO-3-CHLORO-2-IODOBENZENE Benzene, 1-bromo-3-chloro-2-iodo- 1-Bromo-3-chloro-2-iodobenzene,97% 2-Bromo-6-chloroiodobenzene 450412-28-9