1-Bromo-2,3-dimethoxybenzene
- CAS No.
- 5424-43-1
- Chemical Name:
- 1-Bromo-2,3-dimethoxybenzene
- Synonyms
- 3-Bromoveratrole;1-Bromo-2,3-dimethox;3-Bromoveratrole, 95%;1-BROMO-2,3-DIMETHOXYBENZENE;Benzene, 1-bromo-2,3-dimethoxy-;1-[(5-bromo-2,4-dimethoxyphenyl)methyl]-4-(2,5-dimethylphenyl)piperazine
- CBNumber:
- CB6836797
- Molecular Formula:
- C8H9BrO2
- Molecular Weight:
- 217.06
- MDL Number:
- MFCD00185638
- MOL File:
- 5424-43-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Bromo-2,3-dimethoxybenzene | 409158 | 100mg | $305 |
| 1-Bromo-2,3-dimethoxybenzene | B689023 | 1g | $75 |
| 1-Bromo-2,3-dimethoxybenzene | FB140201 | 100mg | $80 |
| 1-Bromo-2,3-dimethoxybenzene | Z4856 | 1g | $131 |
| 1-Bromo-2,3-dimethoxybenzene | FB140201 | 250mg | $160 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2902900000 | |||||||||
| NFPA 704 |
|
1-Bromo-2,3-dimethoxybenzene price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 409158 | 1-Bromo-2,3-dimethoxybenzene | 5424-43-1 | 100mg | $305 | 2021-12-16 | Buy |
| TRC | B689023 | 1-Bromo-2,3-dimethoxybenzene | 5424-43-1 | 1g | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB140201 | 1-Bromo-2,3-dimethoxybenzene | 5424-43-1 | 100mg | $80 | 2021-12-16 | Buy |
| AK Scientific | Z4856 | 1-Bromo-2,3-dimethoxybenzene | 5424-43-1 | 1g | $131 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB140201 | 1-Bromo-2,3-dimethoxybenzene | 5424-43-1 | 250mg | $160 | 2021-12-16 | Buy |
1-Bromo-2,3-dimethoxybenzene Chemical Properties,Uses,Production
Chemical Properties
Colorless liquid
Synthesis
91-16-7
5424-43-1
To a stirred solution of N,N,N',N'-tetramethylethylenediamine (TMEDA, 5.43 mL, 36.19 mmol, 1.0 eq.) in anhydrous ethyl ether (Et2O, 100 mL) was slowly added n-butyllithium (n-BuLi, 22.6 mL, 36.19 mmol, 1.0 eq., 1.6 M hexane solution) at room temperature. The mixture was stirred for 10 minutes and then 1,2-dimethoxybenzene (5.0 g, 36.19 mmol) was added. The reaction mixture was continued to be stirred at room temperature for 2.5 h. The reaction mixture was then cooled to -78 °C and a solution of anhydrous hexane (10 mL) with bromine (Br2, 1.85 mL, 36.19 mmol, 1.0 equiv) was added dropwise. The reaction was kept at -78 °C for 30 min, after which it was slowly warmed to room temperature. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium sulfite (Na2SO3, 20 mL). The reaction mixture was extracted with ethyl acetate (EtOAc, 3 × 30 mL), the organic layers were combined and washed sequentially with water and brine, dried with anhydrous sodium sulfite (Na2SO4) and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (9.5:0.5 to 9:1) to afford 1-bromo-2,3-dimethoxybenzene (6.68 g, 85% yield) as a colorless oil.
References
[1] Tetrahedron Asymmetry, 2013, vol. 24, # 24, p. 1548 - 1555
[2] Patent: WO2009/27679, 2009, A1. Location in patent: Page/Page column 51-52
[3] Journal of Organic Chemistry, 1982, vol. 47, # 12, p. 2393 - 2396
1-Bromo-2,3-dimethoxybenzene Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3992 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9653 | 58 |
| GLR Innovations | +91 9891111994 | info@glrgroup.in | India | 4535 | 58 |
View Lastest Price from 1-Bromo-2,3-dimethoxybenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 1-Bromo-2,3-dimethoxybenzene
5424-43-1
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2019-07-12 | 1-Bromo-2,3-dimethoxybenzene
5424-43-1
|
US $1.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 1-Bromo-2,3-dimethoxybenzene
5424-43-1
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 1-Bromo-2,3-dimethoxybenzene
5424-43-1
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
