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ChemicalBook >> CAS DataBase List >>4-METHYLPYRAZOLE-5-CARBOXYLIC ACID

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID Structure
4-METHYLPYRAZOLE-5-CARBOXYLIC ACID structure
CAS No.
82231-51-4
Chemical Name:
4-METHYLPYRAZOLE-5-CARBOXYLIC ACID
Synonyms
4-methyl-1H-pyrazole-5-carboxylic acid;4-Methyl-1H-pyrazole-3-carboxylic acid;4-Methylpyrazole-3-carboxylic Acid;4-METHYLPYRAZOLE-5-CARBOXYLIC ACID;1H-Pyrazole-3-carboxylic acid, 4-methyl-
CBNumber:
CB62452911
Molecular Formula:
C5H6N2O2
Molecular Weight:
126.11
MDL Number:
MFCD16495896
MOL File:
82231-51-4.mol
MSDS File:
SDS
Last updated:2026-05-28 03:59:08
Product description Number Pack Size Price
4-Methylpyrazole-3-carboxylic acid HDA23151 5g $259.6
4-Methylpyrazole-3-carboxylic acid HDA23151 10g $389.4
4-Methylpyrazole-3-carboxylic acid HDA23151 50g $649
4-Methylpyrazole-3-carboxylic acid HDA23151 100g $909
4-Methylpyrazole-3-carboxylic acid HDA23151 250g $1687.5
More product size
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4-METHYLPYRAZOLE-5-CARBOXYLIC ACID Properties

Boiling point 389.2±22.0 °C(Predicted)
Density 1.404±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 15.75±0.50(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2933199090

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth HDA23151 4-Methylpyrazole-3-carboxylic acid 82231-51-4 5g $259.6 2026-06-04 Buy
Biosynth HDA23151 4-Methylpyrazole-3-carboxylic acid 82231-51-4 10g $389.4 2026-06-04 Buy
Biosynth HDA23151 4-Methylpyrazole-3-carboxylic acid 82231-51-4 50g $649 2026-06-04 Buy
Biosynth HDA23151 4-Methylpyrazole-3-carboxylic acid 82231-51-4 100g $909 2026-06-04 Buy
Biosynth HDA23151 4-Methylpyrazole-3-carboxylic acid 82231-51-4 250g $1687.5 2026-06-04 Buy
Product number Packaging Price Buy
HDA23151 5g $259.6 Buy
HDA23151 10g $389.4 Buy
HDA23151 50g $649 Buy
HDA23151 100g $909 Buy
HDA23151 250g $1687.5 Buy

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID Chemical Properties,Uses,Production

Uses

4-Methylpyrazole-3-carboxylic Acid is a useful research chemical.

Definition

ChEBI: 4-methyl-pyrazole-3-carboxylic acid is a memebr of the class of pyrazoles that is 1H-pyrazole with methyl and carboxylic acid group substituents at positions 4 and 3 respectively. It has a role as a metabolite. It is a member of pyrazoles and a monocarboxylic acid. It derives from a hydride of a 1H-pyrazole.

Synthesis

1H-Pyrazole-3-carboxylic acid, 4-methyl-5-(trimethylsilyl)-, ethyl ester

881668-83-3

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID

82231-51-4

Ethyl 4-methyl-5-trimethylsilylpyrazole-3-carboxylate (3.3 g, 14.6 mmol) was dissolved in ethanol (100 mL) and 1 M aqueous sodium hydroxide (73 mL, 73 mmol). The reaction mixture was heated to reflux for 18 hours and subsequently cooled to room temperature. The reaction solution was acidified with 1 M hydrochloric acid (100 mL) and concentrated to near dryness. The residue was extracted with ethyl acetate (3 x 100 mL), the organic phases were combined, dried over anhydrous sodium sulfate, and concentrated to give 4-methylpyrazole-3-carboxylic acid (1.90 g, 99% yield). The product was confirmed by NMR hydrogen spectrum (DMSO-d6, 400 MHz): δ 13.00 (broad single peak, 2H), 7.50 (single peak, 1H), 2.19 (single peak, 3H).

References

[1] Patent: WO2006/32851, 2006, A1. Location in patent: Page/Page column 69-70; 73

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

1H-Pyrazole-3-carboxylic acid, 4-methyl-5-(trimethylsilyl)-, ethyl ester

Preparation Products

4-Methylpyrazole

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID Suppliers

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
career henan chemical co 		+86-0371-86658258 factory@coreychem.com China 29780 58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd 		027-88013699 17354350817 Ryan@jiutian-bio.com China 5927 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501 product@acmec-e.com China 33301 58
Aladdin Scientific 		tp@aladdinsci.com United States 50108 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+86-18627948422 sale@hdimpurity.com China 3676 58
Suzhou ARTK Medchem Co., Ltd. 		+86-18168183658 sales1@artkmedchem.com China 39007 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		58
Suzhou ARTK Medchem Co., Ltd. 		58
Amadis Chemical Company Limited 		58
PharmaBlock Sciences (Nanjing),Inc. 55

View Lastest Price from 4-METHYLPYRAZOLE-5-CARBOXYLIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-METHYLPYRAZOLE-5-CARBOXYLIC ACID pictures 2020-01-09 4-METHYLPYRAZOLE-5-CARBOXYLIC ACID
82231-51-4
 $5.50 1KG 98%min 1kg-100kg Career Henan Chemical Co

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID Spectrum

4-METHYLPYRAZOLE-5-CARBOXYLIC ACID(82231-51-4)1HNMR

82231-51-4(4-METHYLPYRAZOLE-5-CARBOXYLIC ACID)Related Search:

Ethyl 5-amino-4-cyano-1-phenyl-1H-pyrazole-3-carboxylate 4-METHYLPYRAZOLE-5-CARBOXYLIC ACID 4,4'-BIS[3-CARBOXY-5-OXO-1-(4-SULFOPHENYL)-2-PYRAZOLIN-4-YL]TRIMETHINE OXONOLE DIPOTASSIUM SALT 4-Methylpyrazole ETHYL 4-CYANO-1H-PYRAZOLE-5-CARBOXYLATE
AKOS B025767 ETHYL 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4-CYANO-1H-PYRAZOLE-5-CARBOXYLATE METHYL 3-(2-CHLORO-6-FLUOROPHENYL)-5-[3-(ETHOXYCARBONYL)-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]-4-ISOXAZOLECARBOXYLATE METHYL 3-(2-CHLOROPHENYL)-5-[1-(2,4-DICHLOROPHENYL)-3-(ETHOXYCARBONYL)-1H-PYRAZOL-4-YL]-4-ISOXAZOLECARBOXYLATE 2,5-DIPHENYL-2 H-PYRAZOLE-3,4-DICARBOXYLIC ACID
ETHYL 4-CYANO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-5-CARBOXYLATE METHYL 3-(2-CHLOROPHENYL)-5-[3-(ETHOXYCARBONYL)-1-(4-METHYLPHENYL)-1H-PYRAZOL-4-YL]-4-ISOXAZOLECARBOXYLATE METHYL 5-[1-(2-CHLOROPHENYL)-3-(ETHOXYCARBONYL)-1H-PYRAZOL-4-YL]-3-(2,6-DICHLOROPHENYL)-4-ISOXAZOLECARBOXYLATE IFLAB-BB F2124-0058 ETHYL 4-CYANO-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-5-CARBOXYLATE
4-[5-(3-carboxy-5-hydroxy-1-phenyl-1H-pyrazol-4-yl)penta-2,4-dienylidene]-4,5-dihydroxy-5-oxo-1-phenyl-1H-pyrazole-3-carboxylic acid 4-[3-[3-carboxy-5-hydroxy-1-(4-sulphophenyl)-1H-pyrazol-4-yl]allylidene]-4,5-dihydro-5-oxo-1-(4-sulphophenyl)-1H-pyrazole-3-carboxylic acid METHYL 5-[1-(3-CHLOROPHENYL)-3-(ETHOXYCARBONYL)-1H-PYRAZOL-4-YL]-3-(2,6-DICHLOROPHENYL)-4-ISOXAZOLECARBOXYLATE

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4-METHYLPYRAZOLE-5-CARBOXYLIC ACID 4-Methylpyrazole-3-carboxylic Acid 1H-Pyrazole-3-carboxylic acid, 4-methyl- 4-Methyl-1H-pyrazole-3-carboxylic acid 4-methyl-1H-pyrazole-5-carboxylic acid 82231-51-4