5-broMo-1H-indole-7-carboxaMide
- CAS No.
- 860624-91-5
- Chemical Name:
- 5-broMo-1H-indole-7-carboxaMide
- Synonyms
- 5-broMo-1H-indole-7-carboxaMid;5-broMo-1H-indole-7-carboxaMide;1H-Indole-7-carboxamide, 5-bromo-
- CBNumber:
- CB62563127
- Molecular Formula:
- C9H7BrN2O
- Molecular Weight:
- 239.07
- MDL Number:
- MFCD27930237
- MOL File:
- 860624-91-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-bromo-1H-indole-7-carboxamide 95+% | CD11042713 | 1g | $518 |
| 5-bromo-1H-indole-7-carboxamide 95% | A420214 | 250mg | $181 |
| 5-bromo-1H-indole-7-carboxamide | 860624915 | 1g | $413.56 |
| 5-bromo-1H-indole-7-carboxamide 95% | CM146753 | 1g | $489 |
5-broMo-1H-indole-7-carboxaMide price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Crysdot | CD11042713 | 5-bromo-1H-indole-7-carboxamide 95+% | 860624-91-5 | 1g | $518 | 2026-05-26 | Buy |
| Ambeed | A420214 | 5-bromo-1H-indole-7-carboxamide 95% | 860624-91-5 | 250mg | $181 | 2021-12-16 | Buy |
| Alichem | 860624915 | 5-bromo-1H-indole-7-carboxamide | 860624-91-5 | 1g | $413.56 | 2021-12-16 | Buy |
| Chemenu | CM146753 | 5-bromo-1H-indole-7-carboxamide 95% | 860624-91-5 | 1g | $489 | 2021-12-16 | Buy |
5-broMo-1H-indole-7-carboxaMide Chemical Properties,Uses,Production
Synthesis
860624-90-4
860624-91-5
General procedure for the synthesis of 5-bromo-1H-indole-7-carboxylic acid from 5-bromo-1H-indole-7-carboxylic acid: 5-bromo-1H-indole-7-carboxylic acid (10.0 g, 42 mmol) was dissolved in dichloromethane (100 mL) at room temperature, and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC, 9.66 g, 50.4 mmol) was added sequentially. 50.4 mmol), 1-hydroxybenzotriazole (HOBt, 6.81 g, 50.4 mmol) and a methanol solution of ammonia (2.0 M, 84 mL, 168 mmol). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the solvent was removed by evaporation and the residue was extracted by partitioning with ethyl acetate (100 mL) and water (100 mL). The aqueous layer was then extracted twice with ethyl acetate (100 mL x 2), and all organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated to give the crude product 5-bromo-1H-indole-7-carboxamide (10 g, 98% yield). The crude product did not require further purification and could be used directly in the subsequent reaction.LC/MS analysis: m/z 240.0 ([M+H]+), retention time 1.95 min.
References
[1] Patent: US2009/143372, 2009, A1
[2] Patent: WO2005/67923, 2005, A1. Location in patent: Page/Page column 51
[3] Patent: WO2006/34317, 2006, A2. Location in patent: Page/Page column 78
[4] Patent: WO2007/62318, 2007, A2. Location in patent: Page/Page column 40
[5] Patent: WO2005/67923, 2005, A1. Location in patent: Page/Page column 39-40
5-broMo-1H-indole-7-carboxaMide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
5-broMo-1H-indole-7-carboxaMide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 4000 | 55 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4977 | 55 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Nanjing SynTitan Pharmaceutical Co., Ltd. | 025-57027686 17372956142 | li_lan@syntitan.com | China | 9999 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26012 | 58 |
| Shanghai Hongju Pharmaceutical Technology Co., LTD | 18001895509 | 986383309@qq.com | China | 2864 | 58 |
| Allbio pharm Co., Ltd | 1483287082 19962651230 | sales@allbiopharm.com | China | 1420 | 58 |
| Wuhan Wanjian Biotechnology Co., Ltd | 13277087647 | 17771779698@qq.com | China | 9986 | 58 |
