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5-BROMO-6-METHOXY (1H)INDAZOLE

CAS No.
152626-78-3
Chemical Name:
5-BROMO-6-METHOXY (1H)INDAZOLE
Synonyms
5-Bromo-6-methoxy indazole;5-BROMO-6-METHOXY (1H)INDAZOLE;1H-Indazole, 5-bromo-6-methoxy-;5-Bromo-6-methoxy-1H-indazole
CBNumber:
CB82455138
Molecular Formula:
C8H7BrN2O
Molecular Weight:
227.06
MDL Number:
MFCD11007880
MOL File:
152626-78-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:35:45
Product description Number Pack Size Price
5-Bromo-6-methoxy-1H-indazole Aldrich SYX00190 1g $586
5-Bromo-6-methoxy-1H-indazole ≥95% OR30839 1g $39
5-Bromo-6-methoxy-1H-indazole 070180 1.00g $605
5-Bromo-6-methoxy-1H-indazole 070180 5.00g $1714
5-Bromo-6-methoxy-1H-indazole 97% B5191 100mg $25
More product size

5-BROMO-6-METHOXY (1H)INDAZOLE Properties

Boiling point 363.4±22.0 °C(Predicted)
Density 1.678±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka 13.03±0.40(Predicted)
InChI 1S/C8H7BrN2O/c1-12-8-3-7-5(2-6(8)9)4-10-11-7/h2-4H,1H3,(H,10,11)
InChIKey WTPPKDNNECOBGC-UHFFFAOYSA-N
SMILES COc1cc2[nH]ncc2cc1Br
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
HS Code  2933998090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

5-BROMO-6-METHOXY (1H)INDAZOLE price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SYX00190 5-Bromo-6-methoxy-1H-indazole Aldrich 152626-78-3 1g $586 2026-04-30 Buy
Apolloscientific OR30839 5-Bromo-6-methoxy-1H-indazole ≥95% 152626-78-3 1g $39 2026-06-04 Buy
Matrix Scientific 070180 5-Bromo-6-methoxy-1H-indazole 152626-78-3 1.00g $605 2026-05-18 Buy
Matrix Scientific 070180 5-Bromo-6-methoxy-1H-indazole 152626-78-3 5.00g $1714 2026-05-18 Buy
Synthonix B5191 5-Bromo-6-methoxy-1H-indazole 97% 152626-78-3 100mg $25 2026-05-06 Buy
Product number Packaging Price Buy
SYX00190 1g $586 Buy
OR30839 1g $39 Buy
070180 1.00g $605 Buy
070180 5.00g $1714 Buy
B5191 100mg $25 Buy

5-BROMO-6-METHOXY (1H)INDAZOLE Chemical Properties,Uses,Production

Uses

5-bromo-6-methoxy-1H-indazole is a useful chemical for organic synthesis and reactions.

Synthesis

5-bromo-2-fluoro-4-methoxybenzaldehyde

473417-48-0

5-BROMO-6-METHOXY (1H)INDAZOLE

152626-78-3

Step 2: Synthesis of 5-bromo-6-methoxy-1H-indazole (compound A33). 5-Bromo-2-fluoro-4-methoxybenzaldehyde (9 g, 38.6 mmol), o-hydroxylamine hydrochloride (3.23 g, 38.6 mmol) and potassium carbonate (5.87 g, 42.5 mmol) were dissolved in 1,2-dimethoxyethane (90 mL). The reaction mixture was stirred at 100 °C for 1 hour. After completion of the reaction, it was cooled to room temperature, the solids were removed by filtration and the filtrate was concentrated under reduced pressure. To the concentrate was added dimethylacetamide (90 mL) and hydrazine monohydrate (18 mL), and the mixture was stirred at 150 °C overnight. At the end of the reaction, it was cooled to room temperature, water was added to the reaction mixture and the aqueous layer was extracted with ethyl acetate. The organic layers were combined, washed sequentially with water and saturated aqueous sodium chloride and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give a yellow paste compound A33 (8.26 g, yield: 94%).ESI-MS m/z: 227,229 [M + H]+; 1H-NMR (300 MHz, CDCl3) δ (ppm): 3.96 (s, 3H), 6.92 (s, 1H), 7.94 (d, J=1.1 Hz, 2H).

References

[1] Patent: EP2308880, 2011, A1. Location in patent: Page/Page column 47

5-BROMO-6-METHOXY (1H)INDAZOLE Preparation Products And Raw materials

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View Lastest Price from 5-BROMO-6-METHOXY (1H)INDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-BROMO-6-METHOXY (1H)INDAZOLE pictures 2020-01-05 5-BROMO-6-METHOXY (1H)INDAZOLE
152626-78-3
$1.00 1KG 99% 100KG Career Henan Chemical Co
5-BROMO-6-METHOXY (1H)INDAZOLE 1H-Indazole, 5-bromo-6-methoxy- 5-Bromo-6-methoxy indazole 5-Bromo-6-methoxy-1H-indazole 152626-78-3 Indazoles