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1-(3-Chloropropyl)-pyrrolidine

1-(3-Chloropropyl)-pyrrolidine Structure
1-(3-Chloropropyl)-pyrrolidine structure
CAS No.
39743-20-9
Chemical Name:
1-(3-Chloropropyl)-pyrrolidine
Synonyms
Albb-007086;N-CHLOROPROPYL PYRROLIDINE;1-(3-Chloropropyl)-pyrrolidine;Pyrrolidine,1-(3-chloropropyl)-;(3-Chloropropyl)pyrrolidine, HCl
CBNumber:
CB6283924
Molecular Formula:
C7H14ClN
Molecular Weight:
147.65
MDL Number:
MFCD07787234
MOL File:
39743-20-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:10
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1-(3-Chloropropyl)-pyrrolidine Properties

Boiling point 88-89 °C(Press: 22 Torr)
Density 1.016±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
pka 10.10±0.20(Predicted)
Appearance Colorless to light yellow Liquid
InChI InChI=1S/C7H14ClN/c8-4-3-7-9-5-1-2-6-9/h1-7H2
InChIKey SPRTXTPFQKHSBG-UHFFFAOYSA-N
SMILES N1(CCCCl)CCCC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
HazardClass  IRRITANT

1-(3-Chloropropyl)-pyrrolidine price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 143744 1-(3-Chloropropyl)pyrrolidine 39743-20-9 5.00g $666 2026-05-18 Buy
Matrix Scientific 143744 1-(3-Chloropropyl)pyrrolidine 39743-20-9 25.00g $1998 2026-05-18 Buy
Synthonix C43884 1-(3-Chloropropyl)pyrrolidine 96% 39743-20-9 1g $25 2026-05-06 Buy
Synthonix C43884 1-(3-Chloropropyl)pyrrolidine 96% 39743-20-9 5g $60 2026-05-06 Buy
Synthonix C43884 1-(3-Chloropropyl)pyrrolidine 96% 39743-20-9 10g $120 2026-05-06 Buy
Product number Packaging Price Buy
143744 5.00g $666 Buy
143744 25.00g $1998 Buy
C43884 1g $25 Buy
C43884 5g $60 Buy
C43884 10g $120 Buy

1-(3-Chloropropyl)-pyrrolidine Chemical Properties, Uses, Production

Synthesis

Pyrrolidine

123-75-1

1-Bromo-3-chloropropane

109-70-6

1-(3-CHLOROPROPYL)-PYRROLIDINE

39743-20-9

Example 4 Synthesis of 1-(3-chloropropyl)pyrrolidine At 0°C, 186 g (1.18 mol) of 1-bromo-3-chloropropane was dissolved in 200 ml of ether and 2 equivalents of pyrrolidine were slowly added. After addition, the reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the resulting white solid was removed by filtration. Ice-cold 10% hydrochloric acid solution was added to the filtrate and the ether layer was discarded after partitioning. The aqueous phase was alkalized with ice-cold 20% sodium hydroxide solution and subsequently extracted with ether. The organic phases were combined and dried over anhydrous sodium sulfate. The ether was evaporated under reduced pressure and the residue was distilled under reduced pressure at 95 °C/30 mmHg to give 91 g of the target product 1-(3-chloropropyl)pyrrolidine as a pale yellow liquid in 53% yield.

References

[1] Pharmazie, 1980, vol. 35, # 2, p. 69 - 72
[2] Patent: EP1593679, 2005, A1. Location in patent: Page/Page column 27
[3] Patent: US2005/245524, 2005, A1. Location in patent: Page/Page column 27
[4] European Journal of Medicinal Chemistry, 2014, vol. 89, p. 198 - 206
[5] Journal of the American Chemical Society, 1955, vol. 77, p. 2855,2857

1-(3-Chloropropyl)-pyrrolidine Preparation Products And Raw materials

Raw materials

Pyrrolidine 1-Bromo-3-chloropropane Sodium hydroxide Water Hydrochloric acid
Diethyl ether

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Preparation Products

1-(3-Chloropropyl)-pyrrolidine Suppliers

Global Suppliers ( 100)
Supplier Tel Email Country ProdList Advantage
Sci-Sun Technology CO.,Ltd 18252089365 Krain_kerun@163.com China 2877 58
Biokitchen 021-021-021-31663258 13795219287 donghuanwen@126.com China 3080 58
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shangchem Co., Ltd. +86-21-68182121 China 881 52
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China Langchem Inc. 0086-21-58956006 China 7798 57
skychemical Co.Ltd 021-20958197 20965099 sales@skychemical.com China 1182 57
Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291 zdcomcon@126.com China 4094 50
Baiyin Chengze Chemical Technology Co., Ltd. +86 943-8535351 13389336721 sales@chengzechem.com China 300 58
Supplier Advantage
Sci-Sun Technology CO.,Ltd 58
Biokitchen 58
Wuhan Chemwish Technology Co., Ltd 56
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Shangchem Co., Ltd. 52
Shanghai Hanhong Scientific Co.,Ltd. 64
China Langchem Inc. 57
skychemical Co.Ltd 57
Tianjin Derchemist Science & Technology Co., Ltd. 50
Baiyin Chengze Chemical Technology Co., Ltd. 58

1-(3-Chloropropyl)-pyrrolidine Spectrum

1-(3-CHLOROPROPYL)-PYRROLIDINE(39743-20-9)1HNMR

39743-20-9 (1-(3-Chloropropyl)-pyrrolidine) Related Search:

1-(3-Chloropropyl)-pyrrolidine 1-(3-Chloropropyl)-pyrrolidine hydrochloride 1-(3-chloropropanoyl)pyrrolidine 1-((S)-3-Chloro 2-methylpropionyl)-L-proline 3,5-Dioxo-10-oxa-4-azatricyclo[5.2.1.0(2,6)]dec-8-en-4-yl 3-chloro-2,2-dimethylpropanoate
1-(3-Chloro-3-phenylpropyl)pyrrolidine hydrochloride 1-[(2,2-Dichlorocyclopropyl)methyl]pyrrolidine 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)-5,6-dihydropyrimidin-4(3H)-one hydrochloride N-(2-Chloropropyl)pyrrolidine HCl N-(3-Chloropropyl)pyrrolidine maleate salt
1-(3-Chloropropyl)pyrrolidine maleate 1-(2-Chloropropyl)pyrrolidine 1-(3-chloropropyl)pyrrolidin-3-ol (R)-1-(3-chloropropyl)pyrrolidin-3-ol 1-(3-chloropropyl)pyrrolidin-2-one
1-(3-chloropropyl)pyrrolidine-2,5-dione (S)-1-(3-chloropropyl)pyrrolidin-3-ol

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N-CHLOROPROPYL PYRROLIDINE Pyrrolidine,1-(3-chloropropyl)- Albb-007086 (3-Chloropropyl)pyrrolidine, HCl 1-(3-Chloropropyl)-pyrrolidine 39743-20-9