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Propargyl-PEG5-amine

CAS No.
1589522-46-2
Chemical Name:
Propargyl-PEG5-amine
Synonyms
PROPARGYL-PEG5-NH2;3,6,9,12,15-Pentaoxaoctadec-17-yn-1-amine;Alkyne-PEG5-NH2;HC≡C-CH2-PEG6-NH2;NH2-PEG5-Propargyl;Propargyl-PEG5-amine;Propargyl-PEG5-NH2/3,6,9,12,15-Pentaoxaoctadec-17-yn-1-amine;2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethanamine
CBNumber:
CB63062630
Molecular Formula:
C13H25NO5
Molecular Weight:
275.34
MDL Number:
MFCD27977505
MOL File:
1589522-46-2.mol
MSDS File:
SDS
Last updated:2026-07-17 09:03:53
Product description Number Pack Size Price
Propargyl-PEG5-amine ≥95% CS-0109024 250mg $32
Propargyl-PEG5-amine ≥95% CS-0109024 1g $80
Propargyl-PEG5-amine ≥95% CS-0109024 5g $313
Propargyl-PEG5-amine 95% BIPG1726 100mg $25
Propargyl-PEG5-amine 95% BIPG1726 250mg $41
More product size

Propargyl-PEG5-amine Properties

Boiling point 360.4±37.0 °C(Predicted)
Density 1.049±0.06 g/cm3(Predicted)
storage temp. -20°C, protect from light
solubility DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
pka 8.74±0.10(Predicted)
form Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Propargyl-PEG5-amine price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0109024 Propargyl-PEG5-amine ≥95% 1589522-46-2 250mg $32 2026-06-04 Buy
ChemScene CS-0109024 Propargyl-PEG5-amine ≥95% 1589522-46-2 1g $80 2026-06-04 Buy
ChemScene CS-0109024 Propargyl-PEG5-amine ≥95% 1589522-46-2 5g $313 2026-06-04 Buy
Apolloscientific BIPG1726 Propargyl-PEG5-amine 95% 1589522-46-2 100mg $25 2026-06-04 Buy
Apolloscientific BIPG1726 Propargyl-PEG5-amine 95% 1589522-46-2 250mg $41 2026-06-04 Buy
Product number Packaging Price Buy
CS-0109024 250mg $32 Buy
CS-0109024 1g $80 Buy
CS-0109024 5g $313 Buy
BIPG1726 100mg $25 Buy
BIPG1726 250mg $41 Buy

Propargyl-PEG5-amine Chemical Properties,Uses,Production

Description

Propargyl-PEG5-amine is a propargyl linker that is commonly used as a Click Chemistry reagent for copper-catalyzed reactions with azides. The amine moiety reacts with carboxylic acids, activated NHS esters and other carbonyl compounds. The PEG spacer helps improve the water solubility of the molecule in aqueous media.

Biological Activity

Propargyl-PEG5-amine is a non-cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PROTAC linker belonging to the PEG class and can be used to synthesize a series of PROTAC molecules.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

Non-cleavable

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PEGs

Propargyl-PEG5-amine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
airuikechemical co., ltd.
+86-18353166132 sales02@airuikechemical.com China 983 58
Zhengzhou Alfa Chemical Co.,Ltd
+86-18530059196 sale04@alfachem.cn China 9636 58
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Wuhan Borenpharm Co., Ltd
027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
XIAMEN SINOPEG BIOTECH CO., LTD.
+86-0592-7761068 15616186207 changaiwei@sinopeg.com China 1133 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3147 58
Nantong HI-FUTURE Biology Co., Ltd.
+86-18051384581 sales@chemhifuture.com China 3123 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 38999 58
Wuhan Topule Biopharmaceutical Co., Ltd
+86-18327326525 masar@topule.com China 8433 58
Jilin Chinese Academy of Sciences-yanshen Technology
18143011203 info@chemextension.com China 42052 58

View Lastest Price from Propargyl-PEG5-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Propargyl-PEG5-NH2 pictures 2026-07-24 Propargyl-PEG5-NH2
1589522-46-2
1g 98% 1g/bottle, 10g/bottle, 100g/bottle XIAMEN SINOPEG BIOTECH CO., LTD.
Propargyl-PEG5-amine pictures 2026-07-17 Propargyl-PEG5-amine
1589522-46-2
10g TargetMol Chemicals Inc.
Propargyl-PEG5-amine pictures 2025-06-07 Propargyl-PEG5-amine
1589522-46-2
5g >98.00% 5g Xian confluore Biological Technology Co., Ltd.

Propargyl-PEG5-amine Spectrum

Propargyl-PEG5-amine HC≡C-CH2-PEG6-NH2 Alkyne-PEG5-NH2 Propargyl-PEG5-NH2/3,6,9,12,15-Pentaoxaoctadec-17-yn-1-amine 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethanamine NH2-PEG5-Propargyl 3,6,9,12,15-Pentaoxaoctadec-17-yn-1-amine PROPARGYL-PEG5-NH2 1589522-46-2 PROTAC Linker PROTAC peg