2-Hydroxy-5-methylbenzophenone
- CAS No.
- 1470-57-1
- Chemical Name:
- 2-Hydroxy-5-methylbenzophenone
- Synonyms
- RARECHEM FH 1L 0064;2-Benzoyl-4-methylphenol;5-Methyl-2-hydroxybenzophenone;2-Hydroxy-5-methylbenzophenone;2- Hyroxy-5-methyl benzophenone;2'-Hydroxy-5'-Methylbenzophenone;2'-HYDROXY 5'-METHYL BENZOPHENONE;Benzophenone, 2-hydroxy-5-methyl-;2-Hydroxy-5-methylbenzophenone>2-Hydroxy-5-methylbenzophenone 99%
- CBNumber:
- CB6306465
- Molecular Formula:
- C14H12O2
- Molecular Weight:
- 212.24
- MDL Number:
- MFCD00002379
- MOL File:
- 1470-57-1.mol
- MSDS File:
- SDS
| Melting point | 83-85 °C (lit.) |
|---|---|
| Boiling point | 312.08°C (rough estimate) |
| Density | 1.1035 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| pka | 8.24±0.43(Predicted) |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| InChI | 1S/C14H12O2/c1-10-7-8-13(15)12(9-10)14(16)11-5-3-2-4-6-11/h2-9,15H,1H3 |
| InChIKey | OQERFUGURPLBQH-UHFFFAOYSA-N |
| SMILES | Cc1ccc(O)c(c1)C(=O)c2ccccc2 |
| CAS DataBase Reference | 1470-57-1(CAS DataBase Reference) |
| FDA UNII | 85W615BMP7 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29145000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Hydroxy-5-methylbenzophenone price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H38608 | 2-Hydroxy-5-methylbenzophenone 99% | 1470-57-1 | 5g | $63.8 | 2023-06-20 | Buy |
| TCI Chemical | H1008 | 2-Hydroxy-5-methylbenzophenone >97.0%(GC) | 1470-57-1 | 5g | $90 | 2026-04-30 | Buy |
| TCI Chemical | H1008 | 2-Hydroxy-5-methylbenzophenone >97.0%(GC) | 1470-57-1 | 25g | $262 | 2026-04-30 | Buy |
| Biosynth | FH70599 | 2-Hydroxy-5-methylbenzophenone | 1470-57-1 | 0.025kg | $150 | 2026-06-04 | Buy |
| Biosynth | FH70599 | 2-Hydroxy-5-methylbenzophenone | 1470-57-1 | 0.01kg | $150 | 2026-06-04 | Buy |
2-Hydroxy-5-methylbenzophenone Chemical Properties, Uses, Production
Chemical Properties
yellow crystalline powder
Uses
2-Hydroxy-5-methylbenzophenone is a general reagent used in the synthesis of anti-bacterial and anti-fungal agents.
Preparation
Preparation by condensation of benzotrichloride with p-cresol,
in the presence of aluminium chloride in carbon disulfide for 2 h (75%). The 6,12-diphenyl-2,8-dimethyl-6,12-epoxy-6H,12H-dibenzo[b,f] dioxocin, an intermediate compound, was also formed under these conditions (29%). This “dioxocin”, by hydrolysis with concentrated sulfuric acid at r.t., gave the expected ketone (91%);
in the presence of aqueous sodium hydroxide in a water bath for 4 h (33%) or in 32–40% aqueous sodium hydroxide at 70–80° (67%).
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 1924, 1973 DOI: 10.1021/jo00950a030
2-Hydroxy-5-methylbenzophenone Preparation Products And Raw materials
Raw materials
Preparation Products
2-Hydroxy-5-methylbenzophenone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 4000 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
