BCI
- CAS No.
- 1245792-51-1
- Chemical Name:
- BCI
- Synonyms
- (E)-BCI;BCI;BCI ((E)-BCI);BCI - NSC 150117;BCI, 10 mM in DMSO;inhibit,Phosphatase,BCI,Inhibitor;(2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone;1H-Inden-1-one, 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-, (2E)-
- CBNumber:
- CB63146262
- Molecular Formula:
- C22H23NO
- Molecular Weight:
- 317.42
- MDL Number:
- MOL File:
- 1245792-51-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
BCI price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | VZB79251 | (E)-2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one | 1245792-51-1 | 50mg | $993.5 | 2026-06-05 | Buy |
| Biosynth | VZB79251 | (E)-2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one | 1245792-51-1 | 100mg | $1384 | 2026-06-05 | Buy |
| ChemScene | CS-0087241 | BCI 99.73% | 1245792-51-1 | 1mg | $71 | 2026-06-04 | Buy |
| ChemScene | CS-0087241 | BCI 99.73% | 1245792-51-1 | 5mg | $179 | 2026-06-04 | Buy |
| ChemScene | CS-0087241 | BCI 99.73% | 1245792-51-1 | 10mg | $298 | 2026-06-04 | Buy |
BCI Chemical Properties, Uses, Production
Description
BCI ((E)-BCI, compound 1) is an allosteric dual specificity phosphatase (DUSP) inhibitor with EC50 of 13.3 μM and 8.0 μM in cells for DUSP6 and DUSP1, respectively.
Uses
BCI ((E)-BCI) is a DUSP6 (dual specificity phosphatase 6) inhibitor. BCI shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI can be used in inflammatory disease research[1][2].
Definition
ChEBI: (2E)-2-benzylidene-3-(cyclohexylamino)indan-1-one is a 2-benzylidene-3-(cyclohexylamino)indan-1-one in which the double bond has E configuration. An inhibitor of the dual specificity phosphatase 6 (Dusp6). It has a role as an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor and an apoptosis inducer.
References
[1] Korotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15(10):1436-45. DOI:10.1002/cbic.201402000
[2] Zhang F, et al. DUSP6 Inhibitor (E/Z)-BCI Hydrochloride Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Murine Macrophage Cells via Activating the Nrf2 Signaling Axis and Inhibiting the NF-κB Pathway. Inflammation. 2019 Apr;42(2):672-681. DOI:10.1007/s10753-018-0924-2
BCI Preparation Products And Raw materials
Raw materials
Preparation Products
BCI Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4860 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2970 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
View Latest Price from BCI manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | BCI
1245792-51-1
|
$48.00-197.00 | 99.95% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | BCI
1245792-51-1
|
$48.00-197.00 | 99.95% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-30 | BCI
1245792-51-1
|
1KG | 98 | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
