ChemicalBook >> CAS DataBase List >>MMAF-OMe
MMAF-OMe
- CAS No.
- 863971-12-4
- Chemical Name:
- MMAF-OMe
- Synonyms
- MMAF-OMe;MMAF-OMe, 10 mM in DMSO;MONOMETHYL AURISTATIN F METHYL ESTER;ADC Payload,Inhibitor,MMAF-OMe,inhibit,MMAFOMe,MMAF OMe,ADC Cytotoxin;L-Phenylalanine,N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(aR,bR,2S)-b-methoxy-a-methyl-2-pyrrolidinepropanoyl-,methyl ester;L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, methyl ester;Methyl ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalaninate
- CBNumber:
- CB63154034
- Molecular Formula:
- C40H67N5O8
- Molecular Weight:
- 745.99
- MDL Number:
- MFCD30535529
- MOL File:
- 863971-12-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-16 07:06:08
MMAF-OMe price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6020 | MMAF-OMe 96.05% | 863971-12-4 | 5mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-6020 | MMAF-OMe 96.05% | 863971-12-4 | 10mg | $76 | 2026-06-04 | Buy |
| ChemScene | CS-6020 | MMAF-OMe 96.05% | 863971-12-4 | 25mg | $125 | 2026-06-04 | Buy |
| ChemScene | CS-6020 | MMAF-OMe 96.05% | 863971-12-4 | 50mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-6020 | MMAF-OMe 96.05% | 863971-12-4 | 100mg | $260 | 2026-06-04 | Buy |
MMAF-OMe Chemical Properties, Uses, Production
Uses
MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.
IC 50
Auristatin
References
[1] Currier NV, et al. Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis. Mol Cancer Ther. 2016 Jun;15(6):1291-300 DOI:10.1158/1535-7163.MCT-15-0881
MMAF-OMe Preparation Products And Raw materials
Raw materials
Preparation Products
MMAF-OMe Suppliers
Global Suppliers ( 41)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Tianjin Chempharmatech Co.,Ltd. | 022-66211079 13212288319 | sales@chempharmatech.com | China | 944 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Shanghai Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 811 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | 021-57896695 13122526631 | 2885575445@qq.com | China | 9777 | 58 |
863971-12-4 (MMAF-OMe) Related Search:
MMAF-OMe
MONOMETHYL AURISTATIN F METHYL ESTER
L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, methyl ester
ADC Payload,Inhibitor,MMAF-OMe,inhibit,MMAFOMe,MMAF OMe,ADC Cytotoxin
Methyl ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalaninate
MMAF-OMe, 10 mM in DMSO
L-Phenylalanine,N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(aR,bR,2S)-b-methoxy-a-methyl-2-pyrrolidinepropanoyl-,methyl ester
863971-12-4
