ChemicalBook >> CAS DataBase List >>Methylprednisolone acetate
Methylprednisolone acetate
- CAS No.
- 53-36-1
- Chemical Name:
- Methylprednisolone acetate
- Synonyms
- methylprednisolone 21-acetate;Methylprednisolone EP Impurity J;u8210;Mepred;NSC 48985;Vetacortyl;11-beta)-h;depo-medrone;Lumi-6αdepot-medrol
- CBNumber:
- CB6315522
- Molecular Formula:
- C24H32O6
- Molecular Weight:
- 416.51
- MDL Number:
- MFCD00200356
- MOL File:
- 53-36-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 04:20:51
| Product description | Number | Pack Size | Price |
| Methylprednisolone acetate for system suitability European Pharmacopoeia (EP) Reference Standard | Y0001760 | 10 mg | $254 |
| Methylprednisolone acetate for peak identification European Pharmacopoeia (EP) Reference Standard | Y0001736 | 10 μg | $175 |
| Methylprednisolone acetate | PHR1718 | 500mg | $132 |
| Methylprednisolone acetate European Pharmacopoeia (EP) Reference Standard | M1755000 | 110 mg | $254 |
| Methylprednisolone acetate | 1436006 | 200mg | $440 |
| More product size | |||
| Melting point | 192-195°C |
|---|---|
| alpha | D20 +101° (dioxane) |
| Boiling point | 454.82°C (rough estimate) |
| Density | 1.1156 (rough estimate) |
| refractive index | 1.4593 (estimate) |
| storage temp. | Refrigerator |
| solubility | Practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent). |
| pka | 12.41±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]/D 85 to 105°, c =0.5 in chloroform-d |
| InChIKey | PLBHSZGDDKCEHR-OJNHZLOINA-N |
| SMILES | [C@@]12([H])C[C@@H](C3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@H](C[C@]1(C)[C@@](CC[C@@]21[H])(O)C(=O)COC(=O)C)O)C |&1:0,3,10,12,14,16,18,21,r| |
| CAS DataBase Reference | 53-36-1(CAS DataBase Reference) |
| FDA UNII | 43502P7F0P |
| NCI Drug Dictionary | methylprednisolone acetate |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P280 |
| Hazard Codes | Xn |
| Risk Statements | 63-62 |
| Safety Statements | 36/37-24/25 |
| WGK Germany | WGK 3 |
| HS Code | 32041200 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Repr. 2 |
| Toxicity | LD50 oral in rat: > 10gm/kg |
| REACH Registrations | Active |
Methylprednisolone acetate price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001760 | Methylprednisolone acetate for system suitability European Pharmacopoeia (EP) Reference Standard | 53-36-1 | 10 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0001736 | Methylprednisolone acetate for peak identification European Pharmacopoeia (EP) Reference Standard | 53-36-1 | 10 μg | $175 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR1718 | Methylprednisolone acetate | 53-36-1 | 500mg | $132 | 2026-04-30 | Buy |
| Sigma-Aldrich | M1755000 | Methylprednisolone acetate European Pharmacopoeia (EP) Reference Standard | 53-36-1 | 110 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1436006 | Methylprednisolone acetate | 53-36-1 | 200mg | $440 | 2026-04-30 | Buy |
Methylprednisolone acetate Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Methylprednisolone acetate is used as a glucocorticoid.
Uses
6α-Methyl Prednisolone 21-Acetate is used as a glucocorticoid.
Definition
ChEBI: An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.
brand name
Medrol (Pharmacia & Upjohn).
Biological Activity
Long-acting anti-inflammatory corticosteroid th at suppresses lymphocytes-mediated immunologic responses.
Methylprednisolone acetate (Depo-Medrol) is a long-acting anti-inflammatory corticosteroid th at suppresses lymphocytes-mediated immunologic responses. 6-Methylprednisolone acetate binds to intracellular glucocorticoid receptors and inhibits promoter domains of pro-inflammatory genes and hinders secretion of inflammatory cytokines. It effectively treats multiple ailments such as rheumatic and autoimmune diseases, leukemia, multiple myeloma, and Hodgkin's and non-Hodgkin's lymphoma symptoms along with other drugs. MPA improves COVID-19 pneumonia prognosis.
Toxics Screening Level
The initial threshold screening level (ITSL) for methylpredisolone acetate is 43 μg/m3 based on an annual averaging time.
Synthesis of Methylprednisolone acetate from Pregna-1,4-diene-3,20-dione,11,17-dihydroxy-6-methyl-, (6a,11b)- and Acetic acid
Methylprednisolone acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 318)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CHONGQING CHENCHENG PHARMACEUTICAL CO.，LTD. | 15923947264 | lf19823605252@163.com | China | 121 | 58 |
| Jinan Million Pharmaceutical Co., Ltd | 0531-68659554 +8613031714605 | info@millionpharm.com | China | 184 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 964 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from Methylprednisolone acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Methylprednisolone acetate
53-36-1
|
$1.00 | 99% | 200kg | Jinan Million Pharmaceutical Co., Ltd | ||
 |
2026-04-22 | Methylprednisolone Acetate
53-36-1
|
$39.00-95.00 | 99.74% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-01-19 | Methylprednisolone acetate;
53-36-1
|
1G | 99% | 1000 | CHONGQING CHENCHENG PHARMACEUTICAL CO.，LTD. |
-
- Methylprednisolone acetate
53-36-1
- $1.00
- 99%
- Jinan Million Pharmaceutical Co., Ltd
-
- Methylprednisolone Acetate
53-36-1
- $39.00-95.00
- 99.74%
- TargetMol Chemicals Inc.
-
- Methylprednisolone acetate;
53-36-1
- 99%
- CHONGQING CHENCHENG PHARMACEUTICAL CO.，LTD.
53-36-1(Methylprednisolone acetate)Related Search:
depo-medrone
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-
METHYLPREDNISOLONEACETATE,MICRONIZED,USP
21-Acetoxy-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
6a-Methylprednisolone 21-acetate
DepMedalone 40
DepMedalone 80
Mepred
NSC 48985
Pregna-1,4-diene-3,20-dione, 11b,17,21-trihydroxy-6a-methyl-, 21-acetate (6CI, 7CI, 8CI)
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6a,11b)- (9CI)
Vetacortyl
Methylprednisolone Acetate BP/USP/EP
21-Acetoxy-11,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate
acetic acid [2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-3-keto-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester
6α-Methyl Prednisolone 21-Acetate
Methylprednisolone Acetate (200 mg)
Methylprednisolone a
21-Acetoxy-11β,17-dihydroxy-6α-Methylpregna-1,4-diene-3,20-dione
6-alpha-methylprednisolone21-acetate
Lumi-6&alpha
Methylprednisolone Hydrogen Succinate EP Impurity C
Methylprednisolone acetate for peak identification
Methylprednisolone acetate for system suitability
Methylprednisolone EP
Impurity J(Methylprednisolone Acetate)
depo-methylprednisolone
depo-methylprednisoloneacetate
depot-medrol
u8210
urbasoncrystalsuspension
2-((6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-triMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
METHYLPREDNISOLONE ACETATE
MEDROL ACETATE
depo-medrate
1,4-PREGNADIEN-6-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-ACETATE
1,4-PREGNADIEN-6-ALPHA-METHYL-17,21-DIOL-3,11,20-TRIONE ACETATE
6-ALPHA-METHYLPREDNISOLONE ACETATE
6-ALPHA-METHYLPREDNISONE ACETATE
6-METHYL PREDNISOLONE ACETATE
11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate
Methylprednisolone Acetate Api
11-beta)-h
4-diene-3,20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-21-aceta
4-diene-3,20-dione,21-(acetyloxy)-11,17-dihydroxy-6-methyl-pregna-(6-alp
Methylprednisolone Impurity 9(Methylprednisolone EP Impurity J)
Methylprednisolone acetate for peak identification CRS
Methylprednisolone acetate CRS
Methylprednisolone EP Impurity J(Methylprednisolone Acetate,Methylprednisolone Hydrogen Succinate EPImpurity C)
Methylprednisolone 21-acetate Solution in Acetonitrile，1000μg/mL
11beta,17-Dihydroxy-6alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl Acetate
Methylprednisolone acetate USP/EP/BP
Methylprednisolone Acetate (1436006)
5-Diiodo-L-tyrosine dihydrate
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6α,11β)-
1, 4-PREGNADIEN-6α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE 21-ACETATE
C15141720 MethylprednisolonEAcetate
