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2,2'-Dihydroxychalcone

2,2'-Dihydroxychalcone structure

CAS No.: 15131-80-3

Chemical Name:: 2,2'-Dihydroxychalcone

Synonyms: 2,2'-Dihydroxychalcone;2,2'-Dihydroxychalcone;2,2'-Dihydroxychalchone;2,2''-DIHYDROXYCHALCHONE;2,2''-Dihydroxy chalcone;trans-2,2'-dihydroxychalcone;1,3-bis(2-hydroxyphenyl)-2-propen-1-on;1,3-DI(2-HYDROXYPHENYL)PROP-2-EN-1-ONE;Chalcone, 2,2'-dihydroxy- (6ci,7ci,8ci);1,3-bis(2-hydroxyphenyl)-2-propen-1-one

CBNumber:: CB6318442

Molecular Formula:: C15H12O3

Molecular Weight:: 240.25

MDL Number:: MFCD00017715

MOL File:: 15131-80-3.mol

MSDS File:: SDS

Last updated:2026-09-12 18:54:12

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2,2'-Dihydroxychalcone Properties

Melting point	161-162°C
Boiling point	447.1±45.0 °C(Predicted)
Density	1.286±0.06 g/cm3(Predicted)
pka	7.72±0.30(Predicted)
form	solid
InChI	1S/C15H12O3/c16-13-7-3-1-5-11(13)9-10-15(18)12-6-2-4-8-14(12)17/h1-10,16-17H/b10-9+
InChIKey	KSHCTKZLHCSARH-MDZDMXLPSA-N
SMILES	Oc1ccccc1\C=C\C(=O)c2ccccc2O
EWG's Food Scores	1
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects

2,2'-Dihydroxychalcone price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	IDF00045	2,2′-Dihydroxychalcone Aldrich	15131-80-3	1g	$191	2026-04-30	Buy
Biosynth	FD66599	2,2'-Dihydroxychalcone	15131-80-3	0.5g	$214.17	2026-06-04	Buy
Biosynth	FD66599	2,2'-Dihydroxychalcone	15131-80-3	1g	$356.95	2026-06-04	Buy
Biosynth	FD66599	2,2'-Dihydroxychalcone	15131-80-3	2g	$642.52	2026-06-04	Buy
Biosynth	FD66599	2,2'-Dihydroxychalcone	15131-80-3	5g	$1427.8	2026-06-04	Buy

Product number	Packaging	Price	Buy
IDF00045	1g	$191	Buy
FD66599	0.5g	$214.17	Buy
FD66599	1g	$356.95	Buy
FD66599	2g	$642.52	Buy
FD66599	5g	$1427.8	Buy

2,2'-Dihydroxychalcone Chemical Properties,Uses,Production

Uses

2,2′-Dihydroxychalcone, a flavonoid, is a glutathione S-transferase (GST) inhibitor with an IC50 of 28.9 μM in human colon cancer cells. 2,2′-Dihydroxychalcone induces cell cycle arrest and apoptosis in prostate cancer cells. 2,2′-Dihydroxychalcone has anticancer and anti-inflammatory properties[1][2].

References

[1] Ahmed Q Haddad, et al. Antiproliferative mechanisms of the flavonoids 2,2'-dihydroxychalcone and fisetin in human prostate cancer cells. Nutr Cancer. 2010;62(5):668-81. DOI:10.1080/01635581003605524
[2] Kenneth Goh, et al. 2,2'-Dihydroxychalcone, a glutathione transferase inhibitor, sensitises human colon adenocarcinoma cells to chlorambucil and melphalan, but not to actinomycin D. Mol Med Rep. 2008 Jul-Aug;1(4):575-9. PMID:21479453

2,2'-Dihydroxychalcone Preparation Products And Raw materials

Raw materials

Preparation Products

2,2'-Dihydroxychalcone Suppliers

Global( 47)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51389	80
Shanghai SuperLan Chemcial Technique Centre	0-2022843681 15618226720	chaolaichem@foxmail.com	China	9996	58
Yantai ShengKailun Chemical Technology Co., Ltd.	13356901049	3119594100@qq.com	China	7964	55
Jiaxing Deyi Chemical Co., Ltd.	86-0573-85866609 18367600069	945717149@qq.com	China	9505	58
Chengdu Saint - Kay Biotechnology Co., Ltd.	028-85157043 15882256948	676046971@qq.com	China	4183	58
Amel Pharmatech Corporation	027-888-4366503 13986279625	sales@amelpharmatech.com	China	4826	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973; 13621943973	sales@jamxmpharmatech.com	China	1191	58
Zhende Chemical Technology (Shanghai) Co., Ltd.	15601952568	sales4@myuchem.com	China	2999	58
Yantai Boyun Biological Technology Co. Ltd	13793517650 13793517650	2767277144@qq.com	China	2856	58

Supplier	Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Sigma-Aldrich	80
Shanghai SuperLan Chemcial Technique Centre	58
Yantai ShengKailun Chemical Technology Co., Ltd.	55
Jiaxing Deyi Chemical Co., Ltd.	58
Chengdu Saint - Kay Biotechnology Co., Ltd.	58
Amel Pharmatech Corporation	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58
Zhende Chemical Technology (Shanghai) Co., Ltd.	58
Yantai Boyun Biological Technology Co. Ltd	58

View Lastest Price from 2,2'-Dihydroxychalcone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-14	2,2'-Dihydroxy chalcone 15131-80-3	$82.00-267.00		99.70%	10g	TargetMol Chemicals Inc.

2,2'-Dihydroxy chalcone
15131-80-3
$82.00-267.00
99.70%
TargetMol Chemicals Inc.

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