4-Imidazoleacetic acid hydrochloride
- CAS No.
- 3251-69-2
- Chemical Name:
- 4-Imidazoleacetic acid hydrochloride
- Synonyms
- 2-(1H-IMIDAZOL-4-YL)ACETIC ACID HYDROCHLORIDE;I4AA HYDROCHLORIDE;IMIDAZOLEACETIC ACID HCL;4-IMIDAZOLEACETICACIDHCL;Imidazolyl-4-AceticAcidHcl;IMIDAZOLE-4-ACETIC ACID HCL;Imidazole-4-acetic acid HCI;1H-imidazol-5-acetic acid HCl;(4-imidazolyl)acetic aid .HCl;4(1H)-Imidazoleacetic acid HCl
- CBNumber:
- CB6320171
- Molecular Formula:
- C5H7ClN2O2
- Molecular Weight:
- 162.57
- MDL Number:
- MFCD00012698
- MOL File:
- 3251-69-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 218-222 °C(lit.) |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | water: soluble100mg/mL, clear, faintly yellow |
| form | Crystalline Powder |
| color | White to light yellow |
| Water Solubility | Soluble in water. |
| Sensitive | Hygroscopic |
| BRN | 3701591 |
| Stability | Hygroscopic |
| InChI | InChI=1S/C5H6N2O2.ClH/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);1H |
| InChIKey | MWHLCFYPFGFBQO-UHFFFAOYSA-N |
| SMILES | C1(CC(=O)O)N=CNC=1.Cl |
| CAS DataBase Reference | 3251-69-2(CAS DataBase Reference) |
| FDA UNII | ET7A74ROAO |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P271-P261-P280 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 22-24/25-36/37/39-27-26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29332900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
4-Imidazoleacetic acid hydrochloride price More Price(87)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 219991 | 4-Imidazoleacetic acid hydrochloride 98% | 3251-69-2 | 1g | $147 | 2026-04-30 | Buy |
| Sigma-Aldrich | 219991 | 4-Imidazoleacetic acid hydrochloride 98% | 3251-69-2 | 5g | $311 | 2026-04-30 | Buy |
| TCI Chemical | I0229 | Imidazole-4(5)-acetic Acid Hydrochloride >98.0%(T) | 3251-69-2 | 1g | $178 | 2026-04-30 | Buy |
| TCI Chemical | I0229 | Imidazole-4(5)-acetic Acid Hydrochloride >98.0%(T) | 3251-69-2 | 5g | $887 | 2026-04-30 | Buy |
| Usbiological | 280249 | 4-Imidazoleacetic acid HCl Asreported | 3251-69-2 | 1g | $340 | 2026-06-03 | Buy |
4-Imidazoleacetic acid hydrochloride Chemical Properties, Uses, Production
Chemical Properties
WHITE TO LIGHT YELLOW CRYSTALLINE POWDER
Uses
A GABAc antagonistImidazole-4-acetic acid monohydrochloride is used in the preparation of imidazolyl-polyethylenimine modified nanoparticles. It is also used to prepare pyridyl and imidazoyl functionalized carboproteins and potential metal ion chelators. Further, it acts as an imidazole derivative with potential antituberculousis properties. In addition to this, it is used in the generation of acyl guanidine inhibitors of beta-secretas.
Uses
4-Imidazoleacetic acid hydrochloride was used in the synthesis of:
- imidazolyl-polyethylenimine modified nanoparticles
- pyridyl and imidazoyl functionalized carboproteins, potential metal ion chelators
Biological Activity
4-Imidazoleacetic acid hydrochloride is a competitive antagonist at GABAC receptors.
Synthesis
4-Imidazoleacetic acid hydrochloride is synthesized by reaction of imidazole-4(5)-acetic acid,amidine and dilute hydrochloric acid.
in vivo
Imidazoleacetic acid (400 mg/kg; i.p.; single dose) hydrochloride increases the total free GABA pool size in mouse brain without a concomitant increase in the biosynthesis of GABA from glutamate[2].
IC 50
Microbial Metabolite; Human Endogenous Metabolite
4-Imidazoleacetic acid hydrochloride Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai C&W New Material Co., Ltd. | 021-22062033 15921412618 | sales@c-wnewmaterial.com | China | 210 | 58 |
| Nanjing Jipu Chemical Technology Co., Ltd. | 13770529431; | hqxue@163.com | China | 143 | 58 |
| Unibest Pharmaceutical Technology Co., Ltd. | 13735578103 | jzyz@unibestpharma.com | China | 138 | 58 |
| Hangzhou Copiore Chemical Co., Ltd. | 17300981287 13757145729 | sales@copiore.com | China | 291 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from 4-Imidazoleacetic acid hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | (3H-Imidazol-4-yl)-acetic acid HCl
3251-69-2
|
$1.10-8.80 | 1kg | 99% | 500kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-07-15 | Imidazoleacetic acid hydrochloride
3251-69-2
|
$30.00 | 99.50% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | 4-IMIDAZOLEACETIC ACID HYDROCHLORIDE
3251-69-2
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- (3H-Imidazol-4-yl)-acetic acid HCl
3251-69-2
- $1.10-8.80
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Imidazoleacetic acid hydrochloride
3251-69-2
- $30.00
- 99.50%
- TargetMol Chemicals Inc.
-
- 4-IMIDAZOLEACETIC ACID HYDROCHLORIDE
3251-69-2
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
3251-69-2 (4-Imidazoleacetic acid hydrochloride) Related Search:
1of4
