1-Methyl-4-imidazoleacetic acid hydrochloride
- CAS No.
- 35454-39-8
- Chemical Name:
- 1-Methyl-4-imidazoleacetic acid hydrochloride
- Synonyms
- hydrochloride - [M86572];1-METHYL-4-IMIDAZOLE ACETIC ACID HCL;1-Methyl-15N2-imidazol-4-yl acetic acid HCl;2-(1-METHYL-1H-IMIDAZOL-4-YL)ACETIC ACID HCL;MECHAN. MEASURING STATION, AMELUNG*NO. D10013;1-MethyliMidazole-4-acetic acid hydrochloride;1-Methyl-4-imidazoleacetic acid hydrochloride;1-METHYL-4-IMIDAZOLEACETIC ACID HYDROGEN CHLORIDE;1-methyl-1H-imidazol-4-acetic acid monohydrochloride;(1-Methyl-1H-imidazol-4-yl)-acetic acid hydrochloride
- CBNumber:
- CB7759318
- Molecular Formula:
- C6H9ClN2O2
- Molecular Weight:
- 176.6
- MDL Number:
- MFCD00036998
- MOL File:
- 35454-39-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | 3 |
1-Methyl-4-imidazoleacetic acid hydrochloride price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18815 | 1-Methyl-4-imidazoleacetic Acid (hydrochloride) ≥95% | 35454-39-8 | 10mg | $46 | 2026-04-30 | Buy |
| Cayman Chemical | 18815 | 1-Methyl-4-imidazoleacetic Acid (hydrochloride) ≥95% | 35454-39-8 | 50mg | $202 | 2026-04-30 | Buy |
| Cayman Chemical | 18815 | 1-Methyl-4-imidazoleacetic Acid (hydrochloride) ≥95% | 35454-39-8 | 100mg | $355 | 2026-04-30 | Buy |
| Cayman Chemical | 18815 | 1-Methyl-4-imidazoleacetic Acid (hydrochloride) ≥95% | 35454-39-8 | 250mg | $773 | 2026-04-30 | Buy |
| Usbiological | 410043 | 1-Methyl-4-imidazoleacetic Acid Hydrochloride | 35454-39-8 | 100mg | $418 | 2026-06-03 | Buy |
1-Methyl-4-imidazoleacetic acid hydrochloride Chemical Properties, Uses, Production
Description
1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.
Uses
1-Methyl-4-imidazoleacetic Acid Hydrochloride is a metabolite of histamine (H436500), which is produced by mast cells and involved with the inflammatory response. 1-Methyl-4-imidazoleacetic Acid Hydrochloride can also be used to synthesize N-[1-(9,10-methano-9-anthracenylmethyl)-4-piperidinyl]alkanamides and analogs as dopamine D2 receptor antagonists.
References
[1] KERR J W. IDENTIFICATION OF HISTAMINE METABOLITE 1-METHYL, 4-IMIDAZOLE ACETIC ACID IN HUMAN URINE AND ITS ABSENCE IN STATUS ASTHMATICUS.[J]. BMJ: British Medical Journal, 1964, 2 5409: 606-608. DOI: 10.1136/bmj.2.5409.606
[2] J. J. VAN DOORMAAL. Tryptase and histamine metabolites as diagnostic indicators of indolent systemic mastocytosis without skin lesions[J]. Allergy, 2012, 67 5: 683-690. DOI: 10.1111/j.1398-9995.2012.02809.x
[3] BYRTHE J.P.R. VOS BSC Pieter C van V V M Eveline van der Veer PhD, PHD André B M M, PHD , et al. Diminished reliability of tryptase as risk indicator of mastocytosis in older overweight subjects[J]. Journal of Allergy and Clinical Immunology, 2015, 135 3: Pages 792-798. DOI: 10.1016/j.jaci.2014.05.047
[4] A. TSOLAKIS. Histidine decarboxylase and urinary methylimidazoleacetic acid in gastric neuroendocrine cells and tumours.[C]//21 47 1. 2015: 13240-13249. DOI: 10.3748/wjg.v21.i47.13240
1-Methyl-4-imidazoleacetic acid hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
1-Methyl-4-imidazoleacetic acid hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3828 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2277 | 58 |
| Nanjing ShengSai Chemical Co., Ltd. | 025-85205967 13951876367 | shengsaichem@163.com | China | 818 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Nanjing Nohon Biological Technology Co., Ltd. | 025-85767923 18512596075; | sales@nuoxibio.com | China | 975 | 55 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
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