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HO-PEG3-CH2COOH

CAS No.
51951-05-4
Chemical Name:
HO-PEG3-CH2COOH
Synonyms
Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-;PEG3-O-CH2COOH;OH-PEG3-CH2COOH;PROTAC Linker 8;HO-PEG3-CH2COOH;triethylene glycol monoglycolide;2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetic acid;HO-PEG3-CH2COOH/Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-;PEG3OCH2COOH,PEG-3-O-CH2COOH,Inhibitor,PROTAC Linker8,inhibit,PEG3 O CH2COOH,PROTAC Linkers,PROTAC Linker-8
CBNumber:
CB63340561
Molecular Formula:
C8H16O6
Molecular Weight:
208.21
MDL Number:
MFCD24479936
MOL File:
51951-05-4.mol
MSDS File:
SDS
Last updated:2026-05-28 05:44:00

HO-PEG3-CH2COOH Properties

Boiling point 375.2±27.0 °C(Predicted)
Density 1.211±0.06 g/cm3(Predicted)
storage temp. Storage temp. -20°C
form Viscous Liquid
pka 3.39±0.10(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

HO-PEG3-CH2COOH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth BCA95105 HO-PEG3-CH2COOH 51951-05-4 2g $687.5 2026-06-04 Buy
Biosynth BCA95105 HO-PEG3-CH2COOH 51951-05-4 5g $825 2026-06-04 Buy
Biosynth BCA95105 HO-PEG3-CH2COOH 51951-05-4 10g $1237.5 2026-06-04 Buy
ChemScene CS-0100058 PEG3-O-CH2COOH ≥95% 51951-05-4 250mg $65 2026-06-04 Buy
ChemScene CS-0100058 PEG3-O-CH2COOH ≥95% 51951-05-4 1g $173 2026-06-04 Buy
Product number Packaging Price Buy
BCA95105 2g $687.5 Buy
BCA95105 5g $825 Buy
BCA95105 10g $1237.5 Buy
CS-0100058 250mg $65 Buy
CS-0100058 1g $173 Buy

HO-PEG3-CH2COOH Chemical Properties, Uses, Production

Uses

PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based PROTAC linker can be used in the synthesis of SNIPERs[1].

IC 50

PEGs

References

[1] Ohoka N, et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). J Biol Chem. 2017 Mar 17;292(11):4556-4570. DOI:10.1074/jbc.M116.768853

112-27-6
51951-05-4
Synthesis of HO-PEG3-CH2COOH from Triethylene glycol

HO-PEG3-CH2COOH Preparation Products And Raw materials

HO-PEG3-CH2COOH Suppliers

Global Suppliers ( 58)
Supplier Tel Email Country ProdList Advantage
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4534 58
Borenpharm Co., Ltd 027-65563561 sales@borenpharm.com China 1245 55
BioPharmaMatrix,Inc. 0510-86010668 13395169561; sales@biopharmamatrix.com China 5017 55
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9957 58
Shanghai Yihe Biological Technology Co., Ltd. 021-68882955 17721395025 2423903095@qq.com China 5000 58
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Henan Alfachem Co.,Ltd. 0371-55051623 18137891487 3983243027@qq.com China 9974 58
Shanghai SPAR pharmaceutical technology co., LTD 021-000000 admin@jingshipharmatech.com China 9919 58

HO-PEG3-CH2COOH Spectrum

HO-PEG3-CH2COOH triethylene glycol monoglycolide PEG3-O-CH2COOH PROTAC Linker 8 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetic acid OH-PEG3-CH2COOH PEG3OCH2COOH,PEG-3-O-CH2COOH,Inhibitor,PROTAC Linker8,inhibit,PEG3 O CH2COOH,PROTAC Linkers,PROTAC Linker-8 HO-PEG3-CH2COOH/Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]- Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]- 51951-05-4 2051951-05-4 PROTAC LINKER peg