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ChemicalBook >> CAS DataBase List >>N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl)

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl)

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) Structure
N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) structure
CAS No.
2100306-69-0
Chemical Name:
N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl)
Synonyms
N-(PEG2-Boc)-N-bis(PEG2-propargyl);N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl);4,7,13,16-Tetraoxa-10-azanonadec-18-ynoic acid, 10-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
CBNumber:
CB63373718
Molecular Formula:
C25H43NO8
Molecular Weight:
485.61
MDL Number:
MFCD30723248
MOL File:
2100306-69-0.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
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N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) Properties

Boiling point 531.2±45.0 °C(Predicted)
Density 1.060±0.06 g/cm3(Predicted)
storage temp. 2-8°C, protect from light
form Viscous Liquid
pka 6.88±0.50(Predicted)
color Yellow to brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0115681 N-(PEG2-Boc)-N-bis(PEG2-propargyl) ≥95% 2100306-69-0 100mg $150 2026-06-04 Buy
ChemScene CS-0115681 N-(PEG2-Boc)-N-bis(PEG2-propargyl) ≥95% 2100306-69-0 250mg $359 2026-06-04 Buy
BroadPharm bp-23549 N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) 98% 2100306-69-0 100MG $320 2026-05-24 Buy
BroadPharm bp-23549 N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) 98% 2100306-69-0 250MG $650 2026-05-24 Buy
BroadPharm bp-23549 N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) 98% 2100306-69-0 500MG $980 2026-05-24 Buy
Product number Packaging Price Buy
CS-0115681 100mg $150 Buy
CS-0115681 250mg $359 Buy
bp-23549 100MG $320 Buy
bp-23549 250MG $650 Buy
bp-23549 500MG $980 Buy

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) Chemical Properties, Uses, Production

Description

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) is a multi-functional PEG linker with two terminal propargyl groups and a t-butyl ester. The propargyl groups enables formation of triazole linkage with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry. The t-butyl protected carboxyl group can be deprotected under mild acidic conditions.

Uses

N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) Preparation Products And Raw materials

Raw materials

Preparation Products

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Shanghai Huici Pharmaceutical Technology Co., LTD 133-31922809 19372841038 lixing@pharmahuici.com China 853 58
Affinity（Wuhan）Ltd. 15841022315 sales@affinitytech.cn China 2980 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 Gsiyu@solarbio.com China 50460 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Supplier Advantage
Xi'an Confluore Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Zhengzhou Akem Chemical Co., Ltd 58
Shanghai Huici Pharmaceutical Technology Co., LTD 58
Affinity（Wuhan）Ltd. 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Beijing Solarbio Science & Tecnology Co., Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

View Latest Price from N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(PEG2-Boc)-N-bis(PEG2-propargyl) pictures 2026-07-15 N-(PEG2-Boc)-N-bis(PEG2-propargyl)
2100306-69-0
 $36.00-55.00 10g TargetMol Chemicals Inc.
N-(PEG2-Boc)-N-bis(PEG2-propargyl) pictures 2025-06-07 N-(PEG2-Boc)-N-bis(PEG2-propargyl)
2100306-69-0
 250mg >95.00% 250mg Xian confluore Biological Technology Co., Ltd.

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) Spectrum

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl)(2100306-69-0)1HNMR

2100306-69-0 (N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl)) Related Search:

N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) N-(Amino-PEG3)-N-bis(PEG4-Boc) N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester) N-(Acid-PEG2)-N-bis(PEG2-propargyl) N-Me-N-bis(PEG4-C2-Boc)
N,N-Diethanol amine-PEG4-Boc

1of2

N-(t-butyl ester-PEG2)-N-bis(PEG2-propargyl) N-(PEG2-Boc)-N-bis(PEG2-propargyl) 4,7,13,16-Tetraoxa-10-azanonadec-18-ynoic acid, 10-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester 2100306-69-0 C25H43NO8