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ChemicalBook >> CAS DataBase List >>N-(Acid-PEG2)-N-bis(PEG2-propargyl)

N-(Acid-PEG2)-N-bis(PEG2-propargyl)

N-(Acid-PEG2)-N-bis(PEG2-propargyl) Structure
N-(Acid-PEG2)-N-bis(PEG2-propargyl) structure
CAS No.
2100306-49-6
Chemical Name:
N-(Acid-PEG2)-N-bis(PEG2-propargyl)
Synonyms
N-(Acid-PEG2)-N-bis(PEG2-propargyl);N-(PEG2-C2-acid)-N-bis(PEG2-propargyl);4,7,13,16-Tetraoxa-10-azanonadec-18-ynoic acid, 10-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-
CBNumber:
CB43373668
Molecular Formula:
C21H35NO8
Molecular Weight:
429.5
MDL Number:
MFCD30723247
MOL File:
2100306-49-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:29:47
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N-(Acid-PEG2)-N-bis(PEG2-propargyl) Properties

Boiling point 533.6±50.0 °C(Predicted)
Density 1.122±0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO, DCM, DMF
pka 4.27±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

N-(Acid-PEG2)-N-bis(PEG2-propargyl) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0114300 N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) ≥98% 2100306-49-6 100mg $500 2026-06-04 Buy
BroadPharm bp-23550 N-(Acid-PEG2)-N-bis(PEG2-propargyl) 98% 2100306-49-6 100MG $300 2026-05-24 Buy
BroadPharm bp-23550 N-(Acid-PEG2)-N-bis(PEG2-propargyl) 98% 2100306-49-6 250MG $520 2026-05-24 Buy
BroadPharm bp-23550 N-(Acid-PEG2)-N-bis(PEG2-propargyl) 98% 2100306-49-6 500MG $780 2026-05-24 Buy
BroadPharm bp-23550 N-(Acid-PEG2)-N-bis(PEG2-propargyl) 98% 2100306-49-6 1G $1200 2026-05-24 Buy
Product number Packaging Price Buy
CS-0114300 100mg $500 Buy
bp-23550 100MG $300 Buy
bp-23550 250MG $520 Buy
bp-23550 500MG $780 Buy
bp-23550 1G $1200 Buy

N-(Acid-PEG2)-N-bis(PEG2-propargyl) Chemical Properties, Uses, Production

Description

N-(Acid-PEG2)-N-bis(PEG2-propargyl) is reactive with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Acid-PEG2)-N-bis(PEG2-propargyl) Preparation Products And Raw materials

Raw materials

Preparation Products

N-(Acid-PEG2)-N-bis(PEG2-propargyl) Suppliers

Global Suppliers ( 20)
Supplier Tel Email Country ProdList Advantage
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Guangzhou Hongyuan Chemical Co.,Ltd 15817493340 981810490@qq.com China 1577 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Zhejiang Rui 'ao Biological Technology Co.,LTD. 82087565 15757883359 yan@ruiaochem.cn China 712 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38904 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Xi'an Confluore Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Guangzhou Hongyuan Chemical Co.,Ltd 58
Zhengzhou Akem Chemical Co., Ltd 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Zhejiang Rui 'ao Biological Technology Co.,LTD. 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from N-(Acid-PEG2)-N-bis(PEG2-propargyl) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(Acid-PEG2)-N-bis(PEG2-propargyl) pictures 2025-06-07 N-(Acid-PEG2)-N-bis(PEG2-propargyl)
2100306-49-6
 250mg >95.00% 250mg Xian confluore Biological Technology Co., Ltd.

2100306-49-6 (N-(Acid-PEG2)-N-bis(PEG2-propargyl)) Related Search:

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N-(Acid-PEG2)-N-bis(PEG2-propargyl) N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) 4,7,13,16-Tetraoxa-10-azanonadec-18-ynoic acid, 10-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]- 2100306-49-6 C21H35NO8