O-Desmethyl tramadol HCl
- CAS No.
- 80456-81-1
- Chemical Name:
- O-Desmethyl tramadol HCl
- Synonyms
- Desmethyltramadol;O-Desmethyl tramadol HCl;O-Desmethyltramadol, O-DSMT;Phenobarbital Impurity 15 (Benzobarbital);O-Desmethyl Tramadol DISCONTINUED. Please offer D294740;Phenol, 3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-, rel-;(+)-O-Desmethyl TramadolQ: What is (+)-O-Desmethyl Tramadol Q: What is the CAS Number of (+)-O-Desmethyl Tramadol Q: What is the storage condition of (+)-O-Desmethyl Tramadol Q: What are the applications of (+)-O-Desmethyl Tramadol;(+) O Desmethyl Tramadol D6Q: What is (+) O Desmethyl Tramadol D6 Q: What is the CAS Number of (+) O Desmethyl Tramadol D6 Q: What is the storage condition of (+) O Desmethyl Tramadol D6 Q: What are the applications of (+) O Desmethyl Tramadol D6;(-) O Desmethyl Tramadol D6Q: What is (-) O Desmethyl Tramadol D6 Q: What is the CAS Number of (-) O Desmethyl Tramadol D6 Q: What is the storage condition of (-) O Desmethyl Tramadol D6 Q: What are the applications of (-) O Desmethyl Tramadol D6
- CBNumber:
- CB6337436
- Molecular Formula:
- C15H23NO2
- Molecular Weight:
- 249.35
- MDL Number:
- MFCD08063708
- MOL File:
- 80456-81-1.mol
| Boiling point | 403.3±25.0 °C(Predicted) |
|---|---|
| Density | 1.104±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 10.00±0.10(Predicted) |
| FDA UNII | 2WA8F50C3F |
O-Desmethyl tramadol HCl price More Price(1)
O-Desmethyl tramadol HCl Chemical Properties, Uses, Production
Uses
O-Demethyltramadol is a primary active metabolite of Tramadol. O-Demethyltramadol is mainly responsible for its μ-opioid receptor-related analgesic effect. Tramadol is metabolized to O-Demethyltramadol mainly by the cytochrome P450 (CYP) 2D6 enzyme[1].
Definition
ChEBI: O-Desmethyltramadol is an alkylbenzene and a ring assembly.
References
[1] Lee J, et al. Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6. Drug Des Devel Ther. 2019;13:1751-1761. DOI:10.2147/DDDT.S199574
