ChemicalBook >> CAS DataBase List >>2,2,2-Trichloro-1,1-dimethylethyl chloroformate
2,2,2-Trichloro-1,1-dimethylethyl chloroformate
- CAS No.
- 66270-36-8
- Chemical Name:
- 2,2,2-Trichloro-1,1-dimethylethyl chloroformate
- Synonyms
- TCBOC-CHLORIDE;2,2,2-trichloro-1,1-dimethylethyl ester;β,β,β-trichloro-tert-butyl chloroformate;2,2,2-Trichloro-tert-butyl chloroformate;2,2,2-trichloro-1,1-dimethyl chloroformate;β,β,β-trichloro-tert-butoxycarbonyl chloride;2,2,2-trichloro-1,1-dimethyethyl chloroformate;2,2,2-Trichloro-1,1-dimethylethyl chloroformate;BETA,BETA,BETA-TRICHLORO-TERT-BUTYL CHLOROFORMATE;2,2,2-Trichloro-1,1-diMethylethyl chloroforMate 96%
- CBNumber:
- CB6341886
- Molecular Formula:
- C5H6Cl4O2
- Molecular Weight:
- 239.91
- MDL Number:
- MFCD00000801
- MOL File:
- 66270-36-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-09-12 18:54:13
| Melting point | 28-30 °C(lit.) |
|---|---|
| Boiling point | 83-84 °C14 mm Hg(lit.) |
| Density | 1.4953 (estimate) |
| storage temp. | 2-8°C |
| solubility | ethanol: soluble10%, clear, colorless |
| form | solid |
| BRN | 1935464 |
| InChI | InChI=1S/C5H6Cl4O2/c1-4(2,5(7,8)9)11-3(6)10/h1-2H3 |
| InChIKey | GMELMFSDPDSXOZ-UHFFFAOYSA-N |
| SMILES | C(Cl)(OC(C)(C)C(Cl)(Cl)Cl)=O |
| FDA UNII | ND4GQH3PK3 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H314 |
| Precautionary statements | P260-P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 23/24/25-34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2928 6.1/PG 2 |
| WGK Germany | 3 |
| F | 4.5-10-19-21 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 3 Oral Skin Corr. 1B |
2,2,2-Trichloro-1,1-dimethylethyl chloroformate price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 226505 | 2,2,2-Trichloro-1,1-dimethylethyl chloroformate 96% | 66270-36-8 | 5g | $101 | 2026-04-30 | Buy |
| Sigma-Aldrich | 226505 | 2,2,2-Trichloro-1,1-dimethylethyl chloroformate 96% | 66270-36-8 | 25g | $371 | 2026-04-30 | Buy |
| aablocks | AA003F3Y | 2,2,2-Trichloro-1,1-dimethylethyl chloroformate 97% | 66270-36-8 | 1g | $14 | 2026-05-28 | Buy |
| aablocks | AA003F3Y | 2,2,2-Trichloro-1,1-dimethylethyl chloroformate 97% | 66270-36-8 | 5g | $47 | 2026-05-28 | Buy |
| aablocks | AA003F3Y | 2,2,2-Trichloro-1,1-dimethylethyl chloroformate 97% | 66270-36-8 | 10g | $74 | 2026-05-28 | Buy |
2,2,2-Trichloro-1,1-dimethylethyl chloroformate Chemical Properties,Uses,Production
Uses
Used as easily removable acid- and base-stable protecting group for nitrogen, including amino acids and nucleosides; protecting group for alcohols.
General Description
The solvolysis rate constants of 2,2,2-trichloro-1,1-dimethylethyl chloroformate in binary and pure solvents was studied.
Synthesis
2,2,2-Trichloro-t-butoxycarbonyl Chloride is prepared from trichloro-t-butanol with Phosgene1 or triphosgene (Bis(trichloromethyl) Carbonate) (eq 1).
2,2,2-Trichloro-1,1-dimethylethyl chloroformate Preparation Products And Raw materials
Raw materials
Preparation Products
2,2,2-Trichloro-1,1-dimethylethyl chloroformate Suppliers
Global( 65)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BioPharmaMatrix,Inc. | 0510-86010668 13395169561; | sales@biopharmamatrix.com | China | 4976 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Nanjing Datang Pharmaceutical Technology Co., Ltd. | 025-84341491 13951930983 | 821832400@qq.com | China | 300 | 58 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 | |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| parabiochem | 025-83453382-8005 | sale@parabiochem.com | China | 9577 | 55 |
66270-36-8(2,2,2-Trichloro-1,1-dimethylethyl chloroformate)Related Search:
TCBOC-CHLORIDE
BETA,BETA,BETA-TRICHLORO-TERT-BUTOXYCARBONYL CHLORIDE
BETA,BETA,BETA-TRICHLORO-TERT-BUTYL CHLOROFORMATE
Carbonochloridic acid, 2,2,2-trichloro-1,1-dimethylethyl ester
β,β,β-trichloro-tert-butoxycarbonyl chloride
β,β,β-trichloro-tert-butyl chloroformate
TCBoc-chloride, β,β,β-Trichloro-tert-butyl chloroformate, β,β,β-Trichloro-tert-butoxycarbonyl chloride
Chloridocarbonic acid 2,2,2-trichloro-1,1-dimethylethyl ester
1,1,1-trichloro-2-Methylpropan-2-yl carbonochloridate
2,2,2-Trichloro-1,1-diMethylethyl chloroforMate 96%
TCBoc-chloride, β,β,β-Trichloro-tert-butoxycarbonyl chloride
2,2,2-trichloro-1,1-dimethyethyl chloroformate
2,2,2-trichloro-1,1-dimethyl chloroformate
2,2,2-Trichloro-1,1-dimethylethyl carbonochloridate
1,1,1-Trichloro-2-methyl-2-propyl Carbonochloridate
2,2,2-Trichloro-tert-butyl chloroformate
2,2,2-trichloro-1,1-dimethylchloromacetic acidester
2,2,2-trichloro-1,1-dimethylethyl ester
2,2,2-Trichloro-1,1-dimethylethyl chloroformate
66270-36-8
ClCO2CCH32CCl3
Building Blocks
Carbonyl Compounds
Organic Building Blocks
Acid Halides
CHLOROFORMATES
