2,6-Dimethoxypyridine
- CAS No.
- 6231-18-1
- Chemical Name:
- 2,6-Dimethoxypyridine
- Synonyms
- 2,6-DIMETHOXYPYRIDINE;2,6- twoMethoxypyridine;2,6-Dimethoxypyridine>Pyridine, 2,6-dimethoxy-;2,6-Dimethoxypyridine 98%;2,6-Dimethoxypyridine,99%;2,6-Dimethoxypyridine, 98+%;2,6-DIMETHOXY PYRIDINE (TAX INVOICE NO:2;2,6-Dimethoxypyridine ISO 9001：2015 REACH
- CBNumber:
- CB6355892
- Molecular Formula:
- C7H9NO2
- Molecular Weight:
- 139.15
- MDL Number:
- MFCD00006266
- MOL File:
- 6231-18-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 178-180 °C (lit.) |
|---|---|
| Density | 1.053 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 143 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 1.57±0.10(Predicted) |
| Specific Gravity | 1.053 |
| color | Colorless to Almost colorless |
| BRN | 1525332 |
| InChI | InChI=1S/C7H9NO2/c1-9-6-4-3-5-7(8-6)10-2/h3-5H,1-2H3 |
| InChIKey | IBTGEEMBZJBBSH-UHFFFAOYSA-N |
| SMILES | C1(OC)=NC(OC)=CC=C1 |
| CAS DataBase Reference | 6231-18-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyridine, 2,6-dimethoxy-(6231-18-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-37/38-41-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-39-36/37/39-36 | |||||||||
| RIDADR | 1993 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2,6-Dimethoxypyridine price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D137006 | 2,6-Dimethoxypyridine 98% | 6231-18-1 | 100g | $185 | 2026-04-30 | Buy |
| Sigma-Aldrich | D137006 | 2,6-Dimethoxypyridine 98% | 6231-18-1 | 25g | $77 | 2023-06-20 | Buy |
| TCI Chemical | D1918 | 2,6-Dimethoxypyridine >97.0%(GC) | 6231-18-1 | 25g | $73 | 2026-04-30 | Buy |
| Apolloscientific | OR0937 | 2,6-Dimethoxypyridine 98% | 6231-18-1 | 25g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR0937 | 2,6-Dimethoxypyridine 98% | 6231-18-1 | 100g | $37 | 2026-06-04 | Buy |
2,6-Dimethoxypyridine Chemical Properties, Uses, Production
Uses
2,6-Dimethoxypyridine is widely used in drug molecules, such as enzyme inhibitors/agonists, anti-HIV drugs, antibacterial drugs, and anesthetics.
Chemical Properties
clear colorless to light yellow liquid
Synthesis
2402-78-0
67-56-1
6231-18-1
(1) In a 500 mL three-necked flask, 29.6 g (0.2 mol) of 2,6-dichloropyridine, 16 g (0.4 mol) of sodium hydroxide solid, and 200 mL of methanol were added sequentially. A reflux condensing unit was installed, magnetic stirring was turned on and heated to reflux. After maintaining the reflux reaction for 8 hours, the heating was stopped. Most of the methanol solvent was evaporated by rotary evaporator under reduced pressure. After the reaction solution was cooled to room temperature, it was diluted with 100 mL of water. Extraction and separation were carried out with dichloromethane (100 mL×1), and the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the dichloromethane was removed by spin distillation under reduced pressure to obtain the crude 2,6-dimethoxypyridine. Finally, the target fractions were collected by purification via decompression distillation to obtain the colorless and transparent liquid product 2,6-dimethoxypyridine in 94% yield.
References
[1] Patent: CN106905229, 2017, A. Location in patent: Paragraph 0028; 0029
2,6-Dimethoxypyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Wealsun Biotech Co., Ltd | 18351140886; 18351140886 | wealsunbio@126.com | China | 139 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Latest Price from 2,6-Dimethoxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | 2,6-Dimethoxypyridine
6231-18-1
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-02 | 2,6-Dimethoxypyridine
6231-18-1
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-04-04 | 2,6-Dimethoxypyridine
6231-18-1
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2,6-Dimethoxypyridine
6231-18-1
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2,6-Dimethoxypyridine
6231-18-1
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2,6-Dimethoxypyridine
6231-18-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
