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3-CYANOBENZYLAMINE

CAS No.
10406-24-3
Chemical Name:
3-CYANOBENZYLAMINE
Synonyms
AKOS BB-9335;3-CYANOBENZYLAMINE;M-CyanobenzylaMine;α-AMino-M-tolunitrile;1-AMinoMethyl-3-cyanobenzene;Benzonitrile, 3-(aminomethyl)-
CBNumber:
CB6370969
Molecular Formula:
C8H8N2
Molecular Weight:
132.16
MDL Number:
MFCD06797832
MOL File:
10406-24-3.mol
MSDS File:
SDS
Last updated:2026-05-28 03:08:38

3-CYANOBENZYLAMINE Properties

Melting point 102-103 °C
Boiling point 115 °C(Press: 1 Torr)
Density 1.10±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form liquid
pka 8.56±0.10(Predicted)
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P310-P260-P280
RIDADR  2735
HazardClass  8
PackingGroup 
HS Code  2926907090

3-CYANOBENZYLAMINE price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR301027 3-Cyanobenzylamine >98% 10406-24-3 100mg $21 2026-06-04 Buy
Apolloscientific OR301027 3-Cyanobenzylamine >98% 10406-24-3 250mg $24 2026-06-04 Buy
Apolloscientific OR301027 3-Cyanobenzylamine >98% 10406-24-3 1g $29 2026-06-04 Buy
Apolloscientific OR301027 3-Cyanobenzylamine >98% 10406-24-3 5g $93 2026-06-04 Buy
Apolloscientific OR301027 3-Cyanobenzylamine >98% 10406-24-3 25g $365 2026-06-04 Buy
Product number Packaging Price Buy
OR301027 100mg $21 Buy
OR301027 250mg $24 Buy
OR301027 1g $29 Buy
OR301027 5g $93 Buy
OR301027 25g $365 Buy

3-CYANOBENZYLAMINE Chemical Properties,Uses,Production

Uses

3-Cyanobenzylamine is used in the preparation of indole and indazole derivatives as orexin receptor antagonists.

Synthesis

3-(azidomethyl)benzonitrile

328552-90-5

3-CYANOBENZYLAMINE

10406-24-3

3-Azidomethyl-benzenecarbonitrile (12.4 g, 0.078 mol) was used as a raw material and dissolved in ethyl acetate (40 mL). To this solution was added 5% palladium-carbon catalyst (4.0 g) at room temperature and the hydrogenation reaction was carried out overnight under 45 psi hydrogen pressure. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst. Subsequently, the solvent in the filtrate was evaporated to afford 3-aminomethyl-benzenecarbonitrile as a light brown solid (7.87 g, 76% yield). The product was characterized by 1H-NMR (CDCl3): δ 7.62-7.57 (m, 1H), 7.56-7.43 (m, 2H), 7.42-7.31 (m, 1H), 3.87 (s, 2H).

References

[1] Journal of Medicinal Chemistry, 2015, vol. 58, # 3, p. 1067 - 1088
[2] Patent: WO2016/7966, 2016, A2. Location in patent: Paragraph 0031
[3] Patent: US2006/94749, 2006, A1. Location in patent: Page/Page column 11
[4] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 20, p. 3477 - 3482

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View Lastest Price from 3-CYANOBENZYLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-CYANOBENZYLAMINE pictures 2021-07-13 3-CYANOBENZYLAMINE
10406-24-3
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-CYANOBENZYLAMINE pictures 2021-07-10 3-CYANOBENZYLAMINE
10406-24-3
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-CYANOBENZYLAMINE pictures 2020-01-08 3-CYANOBENZYLAMINE
10406-24-3
1KG 98%; 99% 1kg;10kg; 25kg Career Henan Chemical Co
  • 3-CYANOBENZYLAMINE pictures
  • 3-CYANOBENZYLAMINE
    10406-24-3
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • 3-CYANOBENZYLAMINE pictures
  • 3-CYANOBENZYLAMINE
    10406-24-3
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

3-CYANOBENZYLAMINE Spectrum

3-CYANOBENZYLAMINE AKOS BB-9335 1-AMinoMethyl-3-cyanobenzene M-CyanobenzylaMine α-AMino-M-tolunitrile Benzonitrile, 3-(aminomethyl)- 10406-24-3 Anilines, Aromatic Amines and Nitro Compounds