ChemicalBook >> CAS DataBase List >>N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE structure

CAS No.: 127408-31-5

Chemical Name:: N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE

Synonyms: Y-26763;Y 26763,Y26763;N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE;Acetamide, N-[(3S,4R)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxy-

CBNumber:: CB7841565

Molecular Formula:: C14H16N2O4

Molecular Weight:: 276.29

MDL Number:: MFCD00888284

MOL File:: 127408-31-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-11 16:31:51

Product description	Number	Pack Size	Price
Y-26763 ≥98%	21459	1mg	$41
Y-26763 ≥98%	21459	5mg	$128
Y-26763 ≥98%	21459	10mg	$235
Y-26763	21459	1mg	$37
Y-26763	21459	5mg	$116

Request For Quotation

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE Properties

Boiling point	455.4±55.0 °C(Predicted)
Density	1.36±0.1 g/cm3(Predicted)
storage temp.	Store at RT
solubility	Soluble to 100 mM in 1eq. NaOH
form	Powder
pka	8.69±0.60(Predicted)
color	Off-white to yellow
FDA UNII	Q9F3XV8A6X

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21459	Y-26763 ≥98%	127408-31-5	1mg	$41	2026-04-30	Buy
Cayman Chemical	21459	Y-26763 ≥98%	127408-31-5	5mg	$128	2026-04-30	Buy
Cayman Chemical	21459	Y-26763 ≥98%	127408-31-5	10mg	$235	2026-04-30	Buy
Cayman Chemical	21459	Y-26763	127408-31-5	1mg	$37	2024-03-01	Buy
Cayman Chemical	21459	Y-26763	127408-31-5	5mg	$116	2024-03-01	Buy

Product number	Packaging	Price	Buy
21459	1mg	$41	Buy
21459	5mg	$128	Buy
21459	10mg	$235	Buy
21459	1mg	$37	Buy
21459	5mg	$116	Buy

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE Chemical Properties,Uses,Production

Uses

Y-26763, is a Kir6 (KATP) channel opener. It also inhibits glucose-induced insulin secretion in isolated human pancreatic β-cells in vitro. In vivo, it has shown to have hypotension activity in rats and cardioprotective properties in dogs.

Definition

ChEBI: N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-N-hydroxyacetamide is a 1-benzopyran.

Biological Activity

K ATP channel opener and active metabolite of Y-27152 (N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)acetamide ). In vitro, causes relaxation of contracted rat aortic rings (IC 50 = 0.027 mM) and inhibits glucose-induced insulin secretion in isolated human pancreatic b-cells. In vivo, produces hypotension in spontaneously hypertensive rats and displays cardioprotective properties in dogs following systemic administration.

storage

Store at RT

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE Suppliers

Global( 53)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	19956	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9729	58
Jiangsu aikang biomedical research and development co., LTD	025-58859352 17714375163	qzhang@aikonchem.com	China	15525	58
Shanghai Anhua Biotechnology Co., Ltd.	021-61263375 18168859245		China	5958	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58

Supplier	Advantage
Alchem Pharmtech,Inc.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Fan De(Beijing) Biotechnology Co., Ltd.	58
Jiangsu aikang biomedical research and development co., LTD	58
Shanghai Anhua Biotechnology Co., Ltd.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58

View Lastest Price from N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	Y-26763 127408-31-5	$1240.00-2500.00			10g	TargetMol Chemicals Inc.

Y-26763
127408-31-5
$1240.00-2500.00
TargetMol Chemicals Inc.

127408-31-5(N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE)Related Search:

Y-27632 dihydrochloride (R)-4-(1-aMinoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzaMide dihydrochloride Y320 (R)-4-(1-Aminoethyl)-N-1H-pyrrolo[2,3-b]pyridin-4-ylbenzamide Y-27632

3-M-TOLYL-DL-BETA-ALANINOL (S)-1-Phenylethylhydroxylamine 3-(methylaminomethyl)benzonitrile (S)-3-(1-Aminoethyl)benzonitrile 4-TERT-BUTOXYBENZONITRILE

3-CYANOBENZYLAMINE 6-METHYL-CHROMAN-4-YLAMINE HYDROCHLORIDE 4-isopropoxybenzonitrile Benzenemethanamine, 2-(1-methylethoxy)- (9CI) 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI)

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE D(-)-AC-ALPHA-PHENYLGLYCINOL N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE

1of4

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE Y-26763 Acetamide, N-[(3S,4R)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxy- Y 26763,Y26763 127408-31-5 C14H16N2O4 Potassium channel