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ChemicalBook >> CAS DataBase List >>N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Structure
N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE structure
CAS No.
127408-30-4
Chemical Name:
N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE
Synonyms
Y-27152;Y 27152,Y27152;N-(Benzyloxy)-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)acetamide;N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE;Acetamide, N-[(3S,4R)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)-
CBNumber:
CB1837188
Molecular Formula:
C21H22N2O4
Molecular Weight:
366.41
MDL Number:
MFCD00899866
MOL File:
127408-30-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-21 10:31:43
Product description Number Pack Size Price
Y-27152 Asreported 257140 10mg $508
Y-27152 Asreported 257140 50mg $1527
Y-27152 97% AD280080 100MG $250
Y-27152 97% AD280080 250MG $420
Y-27152 97% AD280080 1G $835
Request For Quotation

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Properties

Boiling point 513.4±60.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 5 mM in ethanol with gentle warming and to 25 mM in DMSO
form Powder
pka 13.18±0.60(Predicted)
FDA UNII 3XM5F7WR44

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 257140 Y-27152 Asreported 127408-30-4 10mg $508 2026-06-03 Buy
Usbiological 257140 Y-27152 Asreported 127408-30-4 50mg $1527 2026-06-03 Buy
ACHEMBLOCK AD280080 Y-27152 97% 127408-30-4 100MG $250 2026-05-27 Buy
ACHEMBLOCK AD280080 Y-27152 97% 127408-30-4 250MG $420 2026-05-27 Buy
ACHEMBLOCK AD280080 Y-27152 97% 127408-30-4 1G $835 2026-05-27 Buy
Product number Packaging Price Buy
257140 10mg $508 Buy
257140 50mg $1527 Buy
AD280080 100MG $250 Buy
AD280080 250MG $420 Buy
AD280080 1G $835 Buy

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Chemical Properties,Uses,Production

Uses

Y-27152, is a prodrug of the Kir6 (KATP) channel opener. It has also shown to produce antihypertensive effects in vivo, with minimal tachycardia following oral administration in hypertensive animals.

Definition

ChEBI: N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-N-phenylmethoxyacetamide is a 1-benzopyran.

Biological Activity

Prodrug of the K ATP channel opener Y-26763 (N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxyacetamide ). Inactive in vitro ; fails to modify tension in contracted aortic rings at concentrations up to 1 mM. In vivo, produces long-lasting antihypertensive effects with minimal tachycardia following oral administration in hypertensive animals.

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63645 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Finetech Industry Limited 		+86-27-8746-5837 +86-18627785180 info@finetechnology-ind.com China 9539 58
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740 sales@bicbiotech.com China 5990 58
TargetMol Chemicals Inc. 		13564774135 marketing@targetmol.com United States 19950 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15815 69
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9337 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 027-65388397 18164111589 3321478047@qq.com China 2002 55
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
Supplier Advantage
Alchem Pharmtech,Inc. 		58
TargetMol Chemicals Inc. 		58
Finetech Industry Limited 		58
Nanjing Bicbiotechnology Co., Ltd 		58
TargetMol Chemicals Inc. 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Finetech Industry Limited 58
EMMX Biotechnology LLC 60
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 55
Fan De(Beijing) Biotechnology Co., Ltd. 58

View Lastest Price from N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Y-27152 pictures 2026-04-21 Y-27152
127408-30-4
 $1820.00-3100.00 10g TargetMol Chemicals Inc.
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    127408-30-4
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127408-30-4(N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE)Related Search:

6-METHYL-CHROMAN-4-YLAMINE HYDROCHLORIDE 4-isopropoxybenzonitrile 3-CYANOBENZYLAMINE Benzenemethanamine, 2-(1-methylethoxy)- (9CI) 3-(methylaminomethyl)benzonitrile
3-M-TOLYL-DL-BETA-ALANINOL N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE 4-TERT-BUTOXYBENZONITRILE 2-(3-CYANO-PHENYL)ETHANOL N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE
4-(2-hydroxyethoxy)benzonitrile D(-)-AC-ALPHA-PHENYLGLYCINOL 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI) (S)-1-Phenylethylhydroxylamine (S)-3-(1-Aminoethyl)benzonitrile

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N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Y-27152 N-(Benzyloxy)-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)acetamide Acetamide, N-[(3S,4R)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)- Y 27152,Y27152 127408-30-4 Potassium channel