Dodecamethylcyclohexasiloxane
- CAS No.
- 540-97-6
- Chemical Name:
- Dodecamethylcyclohexasiloxane
- Synonyms
- Cyclohexasiloxane, dodecamethyl-;CYCLOHEXASILOXANE;Dow Corning 246 Fluid;Cyclomethicone 6;Cyclohexasiloxane 6;2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane;2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane;SH 246;DC 246 Fluid;Dow Corning 246
- CBNumber:
- CB6376936
- Molecular Formula:
- C12H36O6Si6
- Molecular Weight:
- 444.92
- MDL Number:
- MFCD00144215
- MOL File:
- 540-97-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | -3°C |
|---|---|
| Boiling point | 245 °C |
| Density | 0,959 g/cm3 |
| vapor pressure | 4.7Pa at 25℃ |
| refractive index | 1.4015 |
| Flash point | >76°C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | liquid |
| Specific Gravity | 0.9672 |
| color | Colourless |
| Odor | at 100.00%. odorless |
| Viscosity | 5.6mm2/s |
| Water Solubility | 5.1μg/L at 23℃ |
| Hydrolytic Sensitivity | 1: no significant reaction with aqueous systems |
| Merck | 14,3403 |
| Henry's Law Constant | 4.0×10-7 mol/(m3Pa) at 25℃, Xu and Kropscott (2012) |
| Stability | Hygroscopic |
| Cosmetics Ingredients Functions |
SOLVENT HAIR CONDITIONING SKIN CONDITIONING - EMOLLIENT |
| Cosmetic Ingredient Review (CIR) | DODECAMETHYLCYCLOHEXASILOXANE (540-97-6) |
| InChI | 1S/C12H36O6Si6/c1-19(2)13-20(3,4)15-22(7,8)17-24(11,12)18-23(9,10)16-21(5,6)14-19/h1-12H3 |
| InChIKey | IUMSDRXLFWAGNT-UHFFFAOYSA-N |
| SMILES | C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 |
| LogP | 8.87 at 23.6℃ |
| Substances of Very High Concern (SVHC) Candidate List | Dodecamethylcyclohexasiloxane (540-97-6) |
| REACH Annex XVII Substances List | Dodecamethylcyclohexasiloxane (540-97-6) |
| CAS DataBase Reference | 540-97-6(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | XHK3U310BA |
| EPA Substance Registry System | Dodecamethylcyclohexasiloxane (540-97-6) |
| UNSPSC Code | 77101502 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H320 | |||||||||
| Precautionary statements | P264-P305+P351+P338+P337+P313 | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| RIDADR | UN 1993C 3 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GW2328550 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | PBT vPvB |
|||||||||
| Hazardous Substances Data | 540-97-6(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Dodecamethylcyclohexasiloxane price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 43216 | Dodecamethylcyclohexasiloxane analytical standard | 540-97-6 | 25mg | $129 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1154900 | Cyclomethicone 6 United States Pharmacopeia (USP) Reference Standard | 540-97-6 | 200mg | $511 | 2026-04-30 | Buy |
| TCI Chemical | D2040 | Dodecamethylcyclohexasiloxane >97.0%(GC) | 540-97-6 | 1mL | $76 | 2026-04-30 | Buy |
| TCI Chemical | D2040 | Dodecamethylcyclohexasiloxane >97.0%(GC) | 540-97-6 | 5mL | $252 | 2026-04-30 | Buy |
| Biosynth | FD22584 | Dodecamethylcyclohexasiloxane | 540-97-6 | 25g | $354 | 2026-06-04 | Buy |
Dodecamethylcyclohexasiloxane Chemical Properties, Uses, Production
Chemical Properties
Clear Colourless Liquid
Uses
cyclohexasiloxane is a silicone-based emollient.
Uses
A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products. Used in dermal exposure and inhalation toxicity study.
Uses
A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products, Dodecamethylcyclohexasiloxane can be used in dermal exposure and inhalation toxicity study.
Definition
ChEBI: Dodecamethylcyclohexasiloxane is an organosilicon compound.
General Description
Dodecamethylcyclohexasiloxane belonging to the class of cyclic volatile methylsiloxanes is identified as a potent environmental contaminant, most prominently found in biota, biosolid samples, soil, sediment samples, wastewaters, etc. These compounds are used as fragrance carriers or solvents in household products, personal care products, cleaning agents and as precursors in the manufacture of silicone polymers.
Flammability and Explosibility
Non flammable
Toxics Screening Level
The initial threshold screening level (ITSL) for dodecamethylcyclohexasiloxane is 400 μg/m3 based on an annual averaging time.
Dodecamethylcyclohexasiloxane Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HUNAN CHEMFISH SCIENTIFIC CO.,LTD | 85521272 18932438858 | sales@chemfish.com | China | 7780 | 58 |
| Wuhan Carnoss Technology Co., LTD | 18064039730 | 3127859172@qq.com | China | 6716 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Chembridge International Corp.(Taipei/Dongguan/Nanjing) | 025-84712192 | china@chembridge.net | China | 192 | 62 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| AB Specialty Silicones Nantong Co.,Ltd | 18151323200 | morgan.wang@andisil.cn | China | 52 | 55 |
View Latest Price from Dodecamethylcyclohexasiloxane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | DODECAMETHYLCYCLOHEXASILOXANE
540-97-6
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-05-28 | Dodecamethylcyclohexasiloxane
540-97-6
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-06-27 | Dodecamethylcyclohexasiloxane
540-97-6
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- DODECAMETHYLCYCLOHEXASILOXANE
540-97-6
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Dodecamethylcyclohexasiloxane
540-97-6
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Dodecamethylcyclohexasiloxane
540-97-6
- $0.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
