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MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2

MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2 structure

CAS No.: 192723-42-5

Chemical Name:: MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2

Synonyms: TACE substrate;MCA-PLAQAV(DPA)RSSSR-NH2;MCA-PLAQAVDAP(DNP)RSSSR-NH2;Mca-PLAQAVDap(Dnp)RSSRSR-NH2;TACE SUBSTRATE II, FLUOROGENIC;FLUORESCENT PEPTIDE SUBSTRATE III;ADAM-17 SUBSTRATE II, FLUOROGENIC;Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide;TNF-ALPHA CONVERTASE ENZYME SUBSTRATE, FLUOROGENIC;Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide (hum

CBNumber:: CB6377155

Molecular Formula:: C69H103N23O24

Molecular Weight:: 1638.7

MDL Number:: MFCD01318847

MOL File:: 192723-42-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:54:14

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MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2 Properties

Density	1.56±0.1 g/cm3(Predicted)
storage temp.	-15°C
pka	12.49±0.46(Predicted)
Sequence	{Mca}-Pro-Leu-Ala-Gln-Ala-Val-{Dpa}-Arg-Ser-Ser-Ser-Arg-NH2

MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FM110936	Mca-(endo-1a-Dap (Dnp))-TNF-a (-5 to +6) amide (human) trifluoroacetate salt	192723-42-5	500ug	$900	2026-06-04	Buy
Biosynth	FM110936	Mca-(endo-1a-Dap (Dnp))-TNF-a (-5 to +6) amide (human) trifluoroacetate salt	192723-42-5	1000ug	$900	2026-06-04	Buy
Biosynth	FM110936	Mca-(endo-1a-Dap (Dnp))-TNF-a (-5 to +6) amide (human) trifluoroacetate salt	192723-42-5	250ug	$900	2026-06-04	Buy
Biosynth	FM110936	Mca-(endo-1a-Dap (Dnp))-TNF-a (-5 to +6) amide (human) trifluoroacetate salt	192723-42-5	2000ug	$1020	2026-06-04	Buy
Biosynth	FM110936	Mca-(endo-1a-Dap (Dnp))-TNF-a (-5 to +6) amide (human) trifluoroacetate salt	192723-42-5	5000ug	$2250	2026-06-04	Buy

Product number	Packaging	Price	Buy
FM110936	500ug	$900	Buy
FM110936	1000ug	$900	Buy
FM110936	250ug	$900	Buy
FM110936	2000ug	$1020	Buy
FM110936	5000ug	$2250	Buy

MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2 Chemical Properties, Uses, Production

Uses

Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE; ADAM17), ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis[1].

IC 50

ADAM10; ADAM17

References

[1] Yi Wang, et al. Protease assay method using site-specific fluorescence dye labeled protein as substrate. US9708638. 2017.
[2] Haga S, et al. TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compounds. Antiviral Res. 2010 Mar;85(3):551-5. DOI:10.1016/j.antiviral.2009.12.001
[3] Inoshima N, et al. Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection. J Invest Dermatol. 2012 May;132(5):1513-6. DOI:10.1038/jid.2011.462
[4] Liang T, et al. KID24, an antibody directed against ADAM9, is a potent inhibitor of tumor growth in vivo[J]. Molecular Cancer Therapeutics, 2007, 6(11_Supplement): C32-C32.

MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2 Suppliers

Global Suppliers ( 43)

Supplier	Tel	Email	Country	ProdList	Advantage
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Creative Peptides		info@creative-peptides.com	United States	6083	56
Nanjing Leon Biological Technology Co., Ltd.	025-84523390 -127; 17705183659	sales@njleonbiotech.com	China	5501	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19087	58
Dideu Industries Group Limited	+8617392712697	1022@dideu.com	China	29090	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58

Supplier	Advantage
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Creative Peptides	56
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	58
Dideu Industries Group Limited	58
Career Henan Chemica Co	58

192723-42-5 (MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2) Related Search:

PSW 2 FULL VERSION ADAM8 Protein, MOUSE (HEK293, HIS) MMP-9 Protein, RAT (HEK293, HIS) Fluorescein 5-isothiocyanate Benzenepropanoic acid, 5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(2,3-dihydro-3-oxo-1,2-benzisoxazol-6-yl)Methoxy]-

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ADAM-17 SUBSTRATE II, FLUOROGENIC MCA-(ENDO-1A-DAP(DNP))-TNF-A (-5 TO +6) AMIDE (HUMAN) MCA-(ENDO-1A-DAP(DNP))-TNF-ALPHA (-5 TO +6) AMIDE (HUMAN) MCA-(ENDO-1A-DAP(DNP))-TUMOR NECROSIS FACTOR-ALPHA (-5 TO +6) AMIDE (HUMAN) MCA-PRO-LEU-ALA-GLN-ALA-VAL-DPA-ARG-SER-SER-SER-ARG-NH2 MCA-PLAQAVDAP(DNP)RSSSR-NH2 MCA-PLAQAV(DPA)RSSSR-NH2 FLUORESCENT PEPTIDE SUBSTRATE III TACE SUBSTRATE II, FLUOROGENIC TNF-ALPHA CONVERTASE ENZYME SUBSTRATE, FLUOROGENIC Mca-PLAQAVDap(Dnp)RSSRSR-NH2 L-Argininamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl- (9CI) L-Argininamide,1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl- MCA-PRO-LEU-ALA-GLN-ALA-VAL-DAP(DNP)-ARG-SER-SER-SER-ARG-NH2 USP/EP/BP Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide (human) Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide (human) trifluoroacetate salt Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide Mca-(endo-1a-Dap (Dnp))-TNF-a (-5 to +6) amide (human) trifluoroacetate salt TACE substrate Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide (hum MCA-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2 192723-42-5 C69H103N23O24 peptide