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2-Aminoacetophenone hydrochloride

2-Aminoacetophenone hydrochloride Structure
2-Aminoacetophenone hydrochloride structure
CAS No.
5468-37-1
Chemical Name:
2-Aminoacetophenone hydrochloride
Synonyms
PHENACYLAMINE HYDROCHLORIDE;2-aMino-1-phenylethan-1-one hydrochloride;α-Aminoacetophenone;Compound F0401-0089;2-amino-acetophenonhydrochlo;2-aminophenone hydrochloride;2-amino-acetophenonhydrochloride;O-AMINOACETOPHENONE HYDROCHLORIDE;2-AMINOACETOPHENONE HYDROCHLORIDE;ω-aminoacetophenone hydrochloride
CBNumber:
CB6412186
Molecular Formula:
C8H10ClNO
Molecular Weight:
171.62
MDL Number:
MFCD00012873
MOL File:
5468-37-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:13:56
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2-Aminoacetophenone hydrochloride Properties

Melting point 194 °C (dec.)(lit.)
storage temp. Refrigerator (+4°C)
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Crystals
color Slightly yellow to beige
BRN 3563173
Stability Hygroscopic
InChI InChI=1S/C8H9NO.ClH/c9-6-8(10)7-4-2-1-3-5-7;/h1-5H,6,9H2;1H
InChIKey CVXGFPPAIUELDV-UHFFFAOYSA-N
SMILES C(C1=CC=CC=C1)(=O)CN.[H]Cl
CAS DataBase Reference 5468-37-1(CAS DataBase Reference)
EWG's Food Scores 1
EPA Substance Registry System Ethanone, 2-amino-1-phenyl-, hydrochloride (5468-37-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26-24/25
WGK Germany  3
RTECS  AM5940000
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29223990
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

2-Aminoacetophenone hydrochloride price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A38207 2-Aminoacetophenone hydrochloride 99% 5468-37-1 1g $50.7 2026-04-30 Buy
Sigma-Aldrich A38207 2-Aminoacetophenone hydrochloride 99% 5468-37-1 5g $110 2026-04-30 Buy
TRC TRC-A580085-5G Alpha-Aminoacetophenone (Mixed Salt, >85%) 5468-37-1 5g $167 2026-06-03 Buy
TRC TRC-A580085-25G Alpha-Aminoacetophenone (Mixed Salt, >85%) 5468-37-1 25g $193 2026-06-03 Buy
TRC TRC-A580085-1G Alpha-Aminoacetophenone (Mixed Salt, >85%) 5468-37-1 1g $140 2026-06-03 Buy
Product number Packaging Price Buy
A38207 1g $50.7 Buy
A38207 5g $110 Buy
TRC-A580085-5G 5g $167 Buy
TRC-A580085-25G 25g $193 Buy
TRC-A580085-1G 1g $140 Buy

2-Aminoacetophenone hydrochloride Chemical Properties, Uses, Production

Chemical Properties

Off-white crystalline

Uses

Mixed Salt of α-Aminoacetophenone, used in the preparation og pseudopeptidic inhibitors of human sirtuins1-3. This action effectually displays antiproliferative protperties in cancer cells. Also used in the preparation of dual δ/μopiod receptor agonists.

Synthesis

To a stirred solution of phenacyl bromide (1 mmol, 1 equiv) in diethyl ether (13 mL) was added hexamethylenetetramine (1 mmol, 1 equiv) all at once and the mixture was stirred for 12 h at room temperature. The resulting solid was filtered, washed with diethyl ether (15 mL), and dried under reduced pressure to afford the quaternary salt, which was next placed in a two-necked round-bottomed flask fitted with a reflux condenser, and EtOH (22 mL) was added to it. Concentrated HCl (0.6 mL) was added, and the mixture was refluxed for 3 h (solid formed). After cooling to room temperature, the solid was filtered, washed with EtOH (20 mL), and dried under vacuum to afford pure 2-Aminoacetophenone hydrochloride.
2-Aminoacetophenone hydrochloride

Purification Methods

Crystallise the salt from Me2CO /EtOH, EtOH/ Et2O, 2-propanol or 2-propanol and a little HCl (slowly after a fe

2-Aminoacetophenone hydrochloride synthesis

70-11-1
5468-37-1
Synthesis of 2-Aminoacetophenone hydrochloride from 2-Bromoacetophenone

2-Aminoacetophenone hydrochloride Preparation Products And Raw materials

Raw materials

Ethanone, 2-azido-1-phenyl- Formamide, N-formyl-N-(2-oxo-2-phenylethyl)- DL-β-Hydroxyphenethylamine hydrochloride Benzoylnitromethane Glycine, N,N-diformyl-, ethyl ester
2-Bromoacetophenone 2-Chloroacetophenone

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Preparation Products

4-Phenylimidazole (S)-1-(4-Phenyl-1H-imidazol-2-yl)ethanamine (S)-(-)-2-Phenylglycinol 2-Amino-1-phenylethanol 1-Amino-2-phenylbutan-2-ol
2-(5-Phenyloxazol-2-yl)phenol 4-Chloro-2,5-diphenyloxazole

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2-Aminoacetophenone hydrochloride Suppliers

Global Suppliers ( 303)
Supplier Tel Email Country ProdList Advantage
Beijing Taiya Jie Technology Development Co., Ltd. 021-33690831-8001 13552411790;18616022633 postmaster@tyjchem.cn China 1541 55
Shanghai Runna Chemical Technology Co., Ltd 13817852019 runnahuagong@126.com China 49 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Beijing Taiya Jie Technology Development Co., Ltd. 55
Shanghai Runna Chemical Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66

View Latest Price from 2-Aminoacetophenone hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Aminoacetophenone hydrochloride pictures 2021-07-13 2-Aminoacetophenone hydrochloride
5468-37-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Aminoacetophenone hydrochloride pictures 2021-07-09 2-Aminoacetophenone hydrochloride
5468-37-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Aminoacetophenone hydrochloride pictures 2021-07-02 2-Aminoacetophenone hydrochloride
5468-37-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

2-Aminoacetophenone hydrochloride Spectrum

2-Aminoacetophenone hydrochloride(5468-37-1)MS2-Aminoacetophenone hydrochloride(5468-37-1)1HNMR2-Aminoacetophenone hydrochloride(5468-37-1)IR12-Aminoacetophenone hydrochloride(5468-37-1)IR22-Aminoacetophenone hydrochloride(5468-37-1)Raman

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2-AMinoacetophenone hydrochloride, 96% 1GR OMEGA-AMINOACETOPHENONE HYDROCHLORIDE (CA. 4% NACL) 2-AMINOACETOPHENONE HYDROCHLORIDE 99% O-aminoacetophenone HCl ,1-(o-aminophenyl)ethanone ω-Aminoacetophenone hydrochloride, Phenacylamine hydrochloride 1-Phenyl-2-aminoethanone·hydrochloride Phenacylamine hydrochloride with 4% NaCl 2-aMino-1-phenylethan-1-one hydrochloride 2-amino-1-phenyl-ethanonhydrochloride 2-Aminoacetophenone hydrochloride,96% 2-amino-acetophenonhydrochlo Acetophenone, 2-aMino-, hydrochloride Ethanone,2-aMino-1-phenyl-, hydrochloride (1:1) 2-Aminoacetophenone*HCl (with ca. 4% NaCl) 2-amino-acetophenonhydrochloride OMEGA-AMINOACETOPHENONE HYDROCHLORIDE O-AMINOACETOPHENONE HYDROCHLORIDE 2-AMINOACETOPHENONE HYDROCHLORIDE 2-AMINO-1-PHENYL-ETHANONE HYDROCHLORIDE ALPHA-AMINOACETOPHENONE HYDROCHLORIDE 2-OXO-2-PHENYL-ETHYL-AMMONIUM, CHLORIDE ETHANONE, 2-AMINO-1-PHENYL-, HYDROCHLORIDE 2-Aminoacetophenone hydrochloride with 4% NaCl w-Amino-acetophinone hydrochloride ω-aminoacetophenone hydrochloride w-Aminoacetophenone hydrochloride aminomethylphenylketone hydrochloride α-Aminoacetophenone (Mixed Salt, >85%) α-Aminoacetophenone α-Aminoacetophenone Hydrochloride 2-aminophenone hydrochloride Compound F0401-0089 Alpha-Aminoacetophenone (Mixed Salt, >85%) PHENACYLAMINE HYDROCHLORIDE 5468-37-1 15468-37-1 5648-37-1 C6H5COCH2NH2HCl C8H9NOClH Organic Building Blocks Ketones Building Blocks C7 to C8 Carbonyl Compounds AMINE Ketones Organic Building Blocks Building Blocks C7 to C8 Carbonyl Compounds Chemical Synthesis