FETMPYP
- CAS No.
- 133314-07-5
- Chemical Name:
- FETMPYP
- Synonyms
- FETMPYP;FEIIITMPYP(CL);FETMPYP PENTACHLORIDE;FE(III)TETRAKIS(1-METHYL-4-PYRIDYL)PORPHYRIN PENTACHLORIDE;Fe(III) meso-Tetra (N-Methyl-4-Pyridyl) porphine pentachloride;5,10,15,20-tetra (1-methyl-4-pyridyl) porphyrin ferric chloride;Iron(III) meso -tetra(N-methyl-4-pyridyl)porphine pentachloride;5,10,15,20-TETRAKIS(N-METHYL-4'-PYRIDYL)PORPHINATO IRON (III) CHLORIDE
- CBNumber:
- CB6412722
- Molecular Formula:
- C45H62N8
- Molecular Weight:
- 715.02738
- MDL Number:
- MFCD00274429
- MOL File:
- 133314-07-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| FeTMPyP Catalyzes the isomerization of peroxynitrite (ONOO?) to nitrate (NO3?) under physiological conditions and at realistic dose-derived concentrations (kcat = 2.2 x 10?M?1s?1). | 341501 | 10MG | $90.6 |
| FeTMPyP ≥98% | 75854 | 10mg | $36 |
| FeTMPyP ≥98% | 75854 | 25mg | $84 |
| FeTMPyP ≥98% | 75854 | 50mg | $155 |
| FeTMPyP ≥98% | 75854 | 100mg | $274 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H319-H315 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| WGK Germany | WGK 1 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
FETMPYP price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 341501 | FeTMPyP Catalyzes the isomerization of peroxynitrite (ONOO?) to nitrate (NO3?) under physiological conditions and at realistic dose-derived concentrations (kcat = 2.2 x 10?M?1s?1). | 10MG | $90.6 | 2026-03-19 | Buy | |
| Cayman Chemical | 75854 | FeTMPyP ≥98% | 133314-07-5 | 10mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 75854 | FeTMPyP ≥98% | 133314-07-5 | 25mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 75854 | FeTMPyP ≥98% | 133314-07-5 | 50mg | $155 | 2024-03-01 | Buy |
| Cayman Chemical | 75854 | FeTMPyP ≥98% | 133314-07-5 | 100mg | $274 | 2024-03-01 | Buy |
FETMPYP Chemical Properties,Uses,Production
Description
FeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.2 x 106 M−1s−1 with a turnover number of 360 ± 170 s−1. The predominant product (>90%) of this reaction is nitrate, with a minor amount of nitrite also formed (~6%), at pH 7.4.
Uses
FeTMPyP is an orally active peroxynitrite (ONOO ) scavenger. FeTMPyP reduces nitrative stress and increases autophagy. FeTMPyP reduces PARP over-activation and neuroinflammation in chronic constriction injury (CCI)-induced rats, and ameliorates functional, behavioral and biochemical deficits[1][2].
References
[1] Zhang S, et al. Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging. Oxid Med Cell Longev. 2020 Jan 25;2020:4252047. DOI:10.1155/2020/4252047
[2] Komirishetty P, et al. FeTMPyP a peroxynitrite decomposition catalyst ameliorated functional and behavioral deficits in chronic constriction injury induced neuropathic pain in rats. Free Radic Res. 2021 Oct;55(9-10):1005-1017. DOI:10.1080/10715762.2021.2010731
FETMPYP Preparation Products And Raw materials
Raw materials
Preparation Products
FETMPYP Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 26644 | 65 |
| Chongqing Xingcan Pharmaceutical Technology Co., Ltd. | 023-13650506873 19923294409 | xingcanyaoye@sina.com | China | 1600 | 58 |
| Chengdu Aslee Biopharmaceuticals, Inc | 028-85305008 02885305008 | 2306208234@qq.com | China | 1006 | 50 |
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