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(1S,2R)-(-)-cis-1-Amino-2-indanol

(1S,2R)-(-)-cis-1-Amino-2-indanol Structure
(1S,2R)-(-)-cis-1-Amino-2-indanol structure
CAS No.
126456-43-7
Chemical Name:
(1S,2R)-(-)-cis-1-Amino-2-indanol
Synonyms
(1S,2R)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL;(1S,2R)-1-AMINO-2-INDANOL;(1S,2R)-CIS-1-AMINO-2-INDANOL;(1S,2R)-(-)-1-AMINO-2-INDANOL;CIS-(1S,2R)-1-AMINO-2-INDANOL;3aR;(1S;(1S,2R) -(−(1S,2R)-(-)-1-amino-2-ol;(1S,2R)-1-Aminoindan-2-o
CBNumber:
CB6417161
Molecular Formula:
C9H11NO
Molecular Weight:
149.19
MDL Number:
MFCD00216655
MOL File:
126456-43-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:16:25
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(1S,2R)-(-)-cis-1-Amino-2-indanol Properties

Melting point 118-121 °C(lit.)
alpha -62 º (c=0.5, CHCl3)
Boiling point 270.27°C (rough estimate)
Density 1.0753 (rough estimate)
refractive index 1.5760 (estimate)
RTECS NK7525500
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
form Powder
pka 14.79±0.40(Predicted)
color White to light beige
optical activity [α]20/D 61°, c = 0.5 in chloroform
Water Solubility slightly soluble
Sensitive Air Sensitive
BRN 4292559
InChI 1S/C9H11NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,8-9,11H,5,10H2/t8-,9+/m1/s1
InChIKey LOPKSXMQWBYUOI-BDAKNGLRSA-N
SMILES N[C@@H]1[C@H](O)Cc2ccccc12
CAS DataBase Reference 126456-43-7(CAS DataBase Reference)
FDA UNII LU3GK925A8
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-36/37/39
RIDADR  3259
WGK Germany  3
F  10-23
TSCA  No
HazardClass  8
HS Code  29052900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

(1S,2R)-(-)-cis-1-Amino-2-indanol price More Price(96)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 440833 (1S,2R)-(?)-cis-1-Amino-2-indanol 99% 126456-43-7 1g $28.5 2026-04-30 Buy
Sigma-Aldrich 440833 (1S,2R)-(?)-cis-1-Amino-2-indanol 99% 126456-43-7 5g $29.7 2026-04-30 Buy
TCI Chemical A1624 (1S,2R)-(-)-1-Amino-2-indanol >98.0%(GC)(T) 126456-43-7 1g $28 2026-04-30 Buy
TCI Chemical A1624 (1S,2R)-(-)-1-Amino-2-indanol >98.0%(GC)(T) 126456-43-7 5g $121 2026-04-30 Buy
Strem Chemicals 07-0200 (1S,2R)-(-)-cis-1-Aminoindan-2-ol, 98% 98% 126456-43-7 1g $34 2026-04-30 Buy
Product number Packaging Price Buy
440833 1g $28.5 Buy
440833 5g $29.7 Buy
A1624 1g $28 Buy
A1624 5g $121 Buy
07-0200 1g $34 Buy

(1S,2R)-(-)-cis-1-Amino-2-indanol Chemical Properties,Uses,Production

Reaction

  1. Ligand component used in the chromium-catalyzed highly selective asymmetric ene reactions between aryl aldehydes and alkoxy- and silyloxyalkenes.
  2. Ligand component for the chromium-catalyzed highly enantioselective o inverse-demand hetero-Diels-Alder reactions of α,β-unsaturated aldehydes.
  3. Ligand component for the magnesium-catalyzed conjugate addition reaction of 1,3-dicarbonyl compounds to nitroalkenes.
  4. Component for stereoselective asymmetric 6π-azaelectrocyclization through the reaction between the (E)-3-
  5. carbonyl-2,4,6-trienal compounds and the (-)-7-alkyl-cis-1-amino-2-indanol derivatives.
  6. Ligand component for palladium-catalzyed asymmetric azaelectrocyclization for the preparation of 2,4-
  7. disubstituted chiral 1,2,5,6-tetrahydropyridines.
  8. Component for organocatalytic conjugate addition of formaldehyde N,N-dialkylhydrazones to β,γ -Unsaturated α-keto esters.
  9. N-Sulfinyl urea organocatalyst component for enantioselective aza-henry reaction.
  10. Component for organocatalytic enantioselective additions of indoles to nitroalkenes.
Reactions of 126456-43-7_1
Reactions of 126456-43-7_2
Reactions of 126456-43-7_3
Reactions of 126456-43-7_4

Chemical Properties

white to light yellow crystal powder

Uses

1S,2R)-(-)-cis-1-Amino-2-indanol may be used to prepare:

  • (-)-1,2,5,6-Tetrahydropyridine by reacting with methyl (E,E)-4-oxo-2-[(2,6,6-trimethylcyclohex-1-enyl)vinyl}but-2-enoate.
  • Oxazaborolidine catalysts, which can catalyze the asymmetric reduction of aromatic ketones with high enantioselectivity.
  • (RS,1S,2R)-(-)-2,4,6-Trimethylbenzenesulfinic acid 1-(2,4,6-trimethylbenzenesulfonylamino)indan-2-yl ester.

Uses

(1S,2R)-(-)-cis-1-Amino-2-indanol is used as a reagent in the synthesis of heterocyclic compounds as integrase inhibiting antiviral agents. It is also a key intermediate of the HIV protease inhibitor, Indinavir (I525000).

General Description

(1S,2R)-(-)-cis-1-Amino-2-indanol is a main constituent of indinavir, a potent HIV (human immunodeficiency virus) protease inhibitor.

(1S,2R)-(-)-cis-1-Amino-2-indanol Preparation Products And Raw materials

Raw materials

Preparation Products

(1S,2R)-(-)-cis-1-Amino-2-indanol Suppliers

Global( 386)Suppliers
Supplier Tel Email Country ProdList Advantage
Gansu Songsheng Pharmaceutical Co. , Ltd. 13705130158 sales@unitechemical.com China 145 58
ZhengZhou Edward Biology Co.,Ltd 13298105281 1522334715@qq.com China 7498 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Gansu Songsheng Pharmaceutical Co. , Ltd. 58
ZhengZhou Edward Biology Co.,Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61

View Lastest Price from (1S,2R)-(-)-cis-1-Amino-2-indanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2026-09-11 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 $5.00 1kg ≥99% 200mt/year Jinan Finer Chemical Co., Ltd
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2026-03-20 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
(1S,2R)-(-)-cis-1-Amino-2-indanol pictures 2025-04-04 (1S,2R)-(-)-cis-1-Amino-2-indanol
126456-43-7
 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.

(1S,2R)-(-)-cis-1-Amino-2-indanol Spectrum

(1S,2R)-(-)-cis-1-Amino-2-indanol(126456-43-7)1HNMR(1S,2R)-(-)-cis-1-Amino-2-indanol(126456-43-7)IR

126456-43-7((1S,2R)-(-)-cis-1-Amino-2-indanol)Related Search:

Aminopyrine Sulfamic acid 2-Indanol 4-Amino-benzenesulfonic acid monosodium salt EC 2.6.1.2
6-Aminocaproic acid Indinavir Acetaminophen Glucosamine tert-Butanesulfinamide
2-Aminophenol Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride tert-Butylsulfonamide
N-[N,O-Isopropylidene-(2R)-hydroxy indan-(1S)-yl]-(2R)-benzyl-(4s,5)-epoxy pentanamide [1(1S,2R),5(S)]-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-[2-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide 3-(Chloromethyl)pyridine

1of4

5R)-LGH447 dihydrochloride (1S,2R)-(-)-cis-1-Amino-2-hydroxyindane 126456-43-7 (1S,2R)-(-)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Amino-2-indanol 126456-43-7 (1S,2R)-(-)-cis-1-Amino-2-indanol,99% (1S, 2R)-Trans-1-AMino-2-indanol (1S,2R)-(-)-1-Amino-2,3-dihydro-1H-inden-2-ol, (1S,2R)-(-)-1-Aminoindan-2-ol (1S,2R)-1-Amino-2,3-dihydro-inden-2-ol (1S,2R)-(-)-cis-1-Amino-2-indanol ,98% (1S 2R)-(-)-cis-1-AMino-2-indanol 7aR)-1-((S)-1-(3-(tert-butyldiMethylsilyloxy)-3-Methylbutoxy)ethyl) -7a-Methylhexahydro-1H-inden-4(2H)-one KT-1-Amino-2-indanol-0001 (1S,2R)-(-)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Amino-2-hydroxyindane (1S,2R)-(-)-1-Amino-2-indanol, >=98% (1S,2R)-1-Amino-2-indanol,99%e.e. (1S,2R)-(-)-CIS-1-AMINO-2-HYDROXYINDANE (1S,2R)-(-)-CIS-1-AMINO-2-INDANOL (1S,2R)-CIS-1-AMINO-2-INDANOL (1S,2R)-(-)-CIS-1-AMINOINDAN-2-OL (1S,2R)-(+)-CIS-1-AMINOINDAN-2-OL (1S,2R)-(-)-1-AMINO-2-HYDROXYINDAN (1S,2R)-1-AMINO-2-HYDROXYINDANE (1S,2R)-(-)-1-AMINO-2-INDANOL (1S,2R)-1-AMINO-INDAN-2-OL CIS-(1S,2R)-1-AMINO-2-INDANOL cis-(1S)-Amino-(2R)-indanol (Is-Cis)L-Amino-2,3-Dihydro-Lh-Inden-2-Ol,IndinavirSulphate, (IS-cis) l-Amino-2,3-Dihydro-lH-Inden-2-ol CIS-(1S,2R)-1-AMINO-INDANE-2-OL (1S,2R)-(1)-cis-1-Amino-2-indanol (1S,2R)-(-)-cis-1-Aminoindan-2-ol,98% (1S,2R)-(-)-CIS-1-AMINO-2-INDANOL 99% (1R,2S)-(-)-cis-a-Amino-2-indanol (1S,2R)-(-)-1-Amino-2-indanol > 1H-Inden-2-ol, 1-amino-2,3-dihydro-, (1S,2R)- Indinavir Impurity 1 （Indinavir EP Impurity A) (1S,2R)-(-)-cis-1-Amino-2-indanol USP/EP/BP (1S,2R)-(-)-cis-1-Amino-2-indanol, 97%, (1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-aminium (1S,2R)-1-Amino-2-indanol/cis-(1S,2R)-1-Amino-2-indanol (1S,2R) -(&minus (1S,2R)-(-) -1-amino-2-indenol (1S,2R)-(?)-cis-1-Amino-2-indanol (1S,2R)-1-aminoindan-2-ol, 98%min (1S,2R)-(-)-1-amino-2-ol (1S,2R)-1-AMINO-2,3-DIHYDRO-1H-INDEN-2-OL (1S,2R)-1-AMINO-2-INDANOL 3aR (1S,2R)-1-Aminoindan-2-o 126456-43-7 126456-43-9 C9H11NO Amino Alcohols (Chiral) Chiral Building Blocks Hydrogenation Organic Building Blocks Chiral Catalysts, Ligands, and Reagents Asymmetric Synthesis