ChemicalBook >> CAS DataBase List >>4'-Chlorodiazepam
4'-Chlorodiazepam
- CAS No.
- 14439-61-3
- Chemical Name:
- 4'-Chlorodiazepam
- Synonyms
- chlorodiazepam;RO 5-4864;Aids080743;Aids-080743;4'-Chlorodiazepam;RO-54864, 4'-chlorodiazepam;4'-Chlorodiazepam >=98% (TLC);TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem;7-chloro-5(4-chlorophe)1,3-dihydro-1-me-1,4-benzodiaz.-2-on;1-Methyl-5-(4-chlorophenyl)-7-chloro-1H-1,4-benzodiazepine-2(3H)-one
- CBNumber:
- CB6430850
- Molecular Formula:
- C16H12Cl2N2O
- Molecular Weight:
- 319.19
- MDL Number:
- MFCD00043406
- MOL File:
- 14439-61-3.mol
- MSDS File:
- SDS
Last updated:2026-09-12 18:54:15
| Melting point | 160-163 °C |
|---|---|
| Boiling point | 517.1±50.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | +2C to +8C |
| solubility | ethanol: 17 mg/mL |
| form | Off-white powder |
| pka | 3.08±0.10(Predicted) |
| color | White to light yellow |
| Water Solubility |
2-hydroxypropyl-β-cyclodextrin: insoluble H2O: insoluble |
| BRN | 685202 |
| InChI | 1S/C16H12Cl2N2O/c1-20-14-7-6-12(18)8-13(14)16(19-9-15(20)21)10-2-4-11(17)5-3-10/h2-8H,9H2,1H3 |
| InChIKey | PUMYFTJOWAJIKF-UHFFFAOYSA-N |
| SMILES | O=C1CN=C(C2=CC=C(Cl)C=C2)C3=CC(Cl)=CC=C3N1C |
| FDA UNII | 2QW0IK1742 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P501 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-24/25 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | DF0500000 |
| F | 10 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
| Hazardous Substances Data | 14439-61-3(Hazardous Substances Data) |
4'-Chlorodiazepam price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C5174 | 4′-Chlorodiazepam ≥98% (TLC) | 14439-61-3 | 5mg | $318.75 | 2026-04-30 | Buy |
| Sigma-Aldrich | 5.08578 | TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem | 14439-61-3 | 10mg | $264 | 2026-04-30 | Buy |
| Sigma-Aldrich | C-234 | 4′-Chlorodiazepam solution 1?mg/mL in methanol, certified reference material, ampule of 1?mL, Cerilliant? | 14439-61-3 | 1ML | $164 | 2024-03-01 | Buy |
| Cayman Chemical | 23105 | 4''-Chlorodiazepam ≥98% | 14439-61-3 | 1mg | $107 | 2026-04-30 | Buy |
| Cayman Chemical | 23105 | 4''-Chlorodiazepam ≥98% | 14439-61-3 | 5mg | $481 | 2026-04-30 | Buy |
4'-Chlorodiazepam Chemical Properties, Uses, Production
Uses
4′-Chlorodiazepam has been used as a translocator protein ligand in mitochondrial functional studies. It has also been used to investigate its protective effects on glucose deprived T98G astrocyte cell lines.
Biochem/physiol Actions
4′-Chlorodiazepam (Ro5-4864) is a potent selective ligand for the mitochondrial translocator protein 18kDa (TSPO), formerly known as the peripheral benzodiazepine receptor (PBR). Ro5-4864 does not bind to GABA(A) receptors and lacks typical benzodiazepine effects, but has been found to be neuroprotective in several studies.
4'-Chlorodiazepam Preparation Products And Raw materials
Raw materials
Preparation Products
14439-61-3 (4'-Chlorodiazepam) Related Search:
7-Chloro-1,3-dihydro-1-methyl-5-(4-chlorophenyl)-2H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-
Aids080743
Aids-080743
7-chloro-1,3-dihydro-1-methyl-5-(p-chlorophenyl)-2h-1,4-benzodiazepin-2-one
7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2h-4-benzodiazepin-2-one
7-chloro-5-(p-chlorophenyl)-1,3-dihydro-1-methyl-2h-4-benzodiazepin-2-one
7-CHLORO-5-(4-CHLOROPHENYL)-1,3-DIHYDRO-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE
7-CHLORO-5-[4'-CHLOROPHENYL]-1,3-DIHYDRO-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE
RO 5-4864
7-chloro-5(4-chlorophe)1,3-dihydro-1-me-1,4-benzodiaz.-2-on
Ro5-4864, 7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one
1-Methyl-5-(4-chlorophenyl)-7-chloro-1H-1,4-benzodiazepine-2(3H)-one
1-Methyl-5-(p-chlorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepine-2-one
1-Methyl-7-chloro-5-(4-chlorophenyl)-1H-1,4-benzodiazepine-2(3H)-one
TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem
4'-Chlorodiazepam >=98% (TLC)
RO-54864, 4'-chlorodiazepam
4'-Chlorodiazepam
chlorodiazepam
14439-61-3
