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FOSFESTROL

CAS No.
522-40-7
Chemical Name:
FOSFESTROL
Synonyms
FOSFESTROL;DIETHYLSTILBESTROL DIPHOSPHATE;DIETHYLSTILBOESTROLDIPHOSPHATE;diethylstilbestrol bisphosphate;diethylstilbesterol diphosphate;stilboestrol bis(dihydrogen phosphate);3-Hexene-3,4-diylbis(4,1-phenylene) bis[dihydrogen (phosphate)];(E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate);alpha,alpha'-diethyl-(e)-4,4'-stilbenediol bis(dihydrogen phosphate);alpha,alpha'-diethyl-, bis(dihydrogen phosphate), (e)-4'-stilbenediol
CBNumber:
CB6443874
Molecular Formula:
C18H22O8P2
Molecular Weight:
428.31
MDL Number:
MFCD00867397
MOL File:
522-40-7.mol
Last updated:2026-05-20 15:45:17

FOSFESTROL Properties

Melting point 250.5°C
storage temp. 2-8°C
form solid
FDA UNII A0E0NMA80F
ATC code L02AA04
EPA Substance Registry System Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis-, bis(dihydrogen phosphate) (522-40-7)

SAFETY

Risk and Safety Statements

HazardClass  IRRITANT

FOSFESTROL price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00DIAS (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate) 95% 522-40-7 100mg $319 2026-05-28 Buy
aablocks AA00DIAS (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate) 95% 522-40-7 250mg $511 2026-05-28 Buy
aablocks AA00DIAS (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate) 95% 522-40-7 1g $992 2026-05-28 Buy
Crysdot CD61000642 (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate) 95+% 522-40-7 1g $772 2026-05-27 Buy
Aronis compounds BBC/528 3-hexene-3,4-diylbis(4,1-phenylene) bis[dihydrogen (phosphate)] 522-40-7 1g $173 2026-05-20 Buy
Product number Packaging Price Buy
AA00DIAS 100mg $319 Buy
AA00DIAS 250mg $511 Buy
AA00DIAS 1g $992 Buy
CD61000642 1g $772 Buy
BBC/528 1g $173 Buy

FOSFESTROL Chemical Properties, Uses, Production

Originator

Stilphostrol,Dome,US,1955

Uses

Diethylstilbestrol Diphosphate USP (Stilphostrol) is used to treat Prostatic carcinoma.

Definition

ChEBI: Diethylstilbestrol diphosphate is an aryl phosphate. It is functionally related to a diethylstilbestrol.

Manufacturing Process

A solution of 1 part of α,α'-diethyl-4,4'-dihydroxystilbene in 5 parts of pyridine is added drop by drop to the strongly cooled solution of 2 parts of phosphorus-hydroxy chloride in 5 parts of pyridine. The mixture soon solidifies to a crystalline magma. It is allowed to stand in ice for hour and then for an hour at room temperature. The mass is then poured into an excess of saturated sodium bicarbonate solution. Unconsumed parent material is removed by extraction with ether. The aqueous solution is then mixed with 2 N hydrochloric acid, whereupon the primary phosphoric acid ester of α,α'- diethyl-4,4'-dihydroxystilbene of the formula is precipitated in the form of a voluminous white powder. By recrystallization or reprecipitation this ester may be further purified.

Therapeutic Function

Estrogen, Antitumor

General Description

Odorless off-white crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Organophosphates, such as FOSFESTROL, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Fire Hazard

Flash point data for FOSFESTROL are not available; however, FOSFESTROL is probably combustible.

FOSFESTROL Preparation Products And Raw materials

Global Suppliers ( 41)
Supplier Tel Email Country ProdList Advantage
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3307 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
AFINE CHEMICALS LIMITED +86-571-85134551 +86-18958018566 info@afinechem.com China 15030 58
Wuhan Ying Yuan Bei Biological Limited 13349903920 1540154086@qq.com China 2994 58
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 +86-17392581500 1015@dideu.com China 3861 58
Harway Pharma CO., LTD 18254622207 18860615010 jerry@harwaypharma.com China 88 58
Guangzhou Yunmen Biotechnology Co., Ltd 0751-18902340975/189023400307 18902340307 3356812514@qq.com China 9225 58
Shaanxi Dideu Medichem Co. Ltd 029-81024372 17792795018 1053@dideu.com China 9999 58

View Latest Price from FOSFESTROL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
[4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate pictures 2018-09-26 [4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate
522-40-7
$35.00 1KG 98%Whatsapp;+8617197824028 6000kg/week Hebei Jiangkai Trading Co., Ltd
FOSFESTROL DIETHYLSTILBOESTROLDIPHOSPHATE alpha,alpha'-diethyl-(e)-4,4'-stilbenediol bis(dihydrogen phosphate) alpha,alpha'-diethyl-, bis(dihydrogen phosphate), (e)-4'-stilbenediol diethylstilbesterol diphosphate 3-Hexene-3,4-diylbis(4,1-phenylene) bis[dihydrogen (phosphate)] (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate) [4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate stilboestrol bis(dihydrogen phosphate) DIETHYLSTILBESTROL DIPHOSPHATE diethylstilbestrol bisphosphate Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis-, 1,1'-bis(dihydrogen phosphate) (e)-4-(4-(4-(Phosphonooxy)phenyl)hex-3-en-3-yl)phenyl dihydrogen phosphate 522-40-7 C18H22O8P2