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3-Fluoro-4-bromo-acetophenone

3-Fluoro-4-bromo-acetophenone Structure
3-Fluoro-4-bromo-acetophenone structure
CAS No.
304445-49-6
Chemical Name:
3-Fluoro-4-bromo-acetophenone
Synonyms
1-(4-broMo-3-fluorophenyl)ethan-1-one;3-Fluoro-4-bromoacetopheone;3-Fluoro-4-bromo-acetophenone;4-BROMO-3-FLUORO-ACETOPHENONE;3-Fluoro-4-bromo-caetophenone;4'-Bromo-3'-fluoroacetophenone;4-Bromo-3-fluoroacetophenone,96%;1-(4-BroMo-3-fluorophenyl)ethanone;Ethanone, 1-(4-broMo-3-fluorophenyl)-;6-acetyl-3-bromo-2-fluoro-1-cyclohexa-2,4-dienone
CBNumber:
CB6465218
Molecular Formula:
C8H6BrFO
Molecular Weight:
217.04
MDL Number:
MFCD00466241
MOL File:
304445-49-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:16
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3-Fluoro-4-bromo-acetophenone Properties

Boiling point 263.3℃
Density 1.535
Flash point 113.0℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Solid
Appearance Off-white to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
HS Code  2914790090
NFPA 704
1
2 0

3-Fluoro-4-bromo-acetophenone price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC501320 4'-Bromo-3'-fluoroacetophenone ≥95% 304445-49-6 1g $21 2026-06-04 Buy
Apolloscientific PC501320 4'-Bromo-3'-fluoroacetophenone ≥95% 304445-49-6 5g $33 2026-06-04 Buy
Apolloscientific PC501320 4'-Bromo-3'-fluoroacetophenone ≥95% 304445-49-6 10g $47 2026-06-04 Buy
Activate Scientific AS8420 4-Bromo-3-fluoro-acetophenone 95% 304445-49-6 1g $81 2026-06-04 Buy
Activate Scientific AS8420 4-Bromo-3-fluoro-acetophenone 95% 304445-49-6 5g $272 2026-06-04 Buy
Product number Packaging Price Buy
PC501320 1g $21 Buy
PC501320 5g $33 Buy
PC501320 10g $47 Buy
AS8420 1g $81 Buy
AS8420 5g $272 Buy

3-Fluoro-4-bromo-acetophenone Chemical Properties, Uses, Production

Synthesis

Methylmagnesium chloride

676-58-4

4-BROMO-3-FLUORO-N-METHOXY-N-METHYL-BENZAMIDE

343564-56-7

3-FLUORO-4-BROMO-ACETOPHENONE

304445-49-6

A tetrahydrofuran solution of 3.00 M methylmagnesium chloride (125 mL, 0.38 mol) was added slowly and dropwise to a tetrahydrofuran (500 mL) solution of 4-bromo-3-fluoro-N-methoxy-N-methylbenzamide (58.5 g, 0.223 mol) at 0 °C. The reaction mixture was stirred continuously at 0 °C for 1 hour. Upon completion of the reaction, the reaction was quenched with pre-cooled saturated ammonium chloride solution (150 mL). The organic layer was separated and the remaining aqueous phase was extracted with ethyl acetate (3 x 50 mL). All organic phases were combined, washed with saturated brine, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford the crude product 3-fluoro-4-bromoacetophenone (48.4 g, 99% yield), which could be used in the subsequent reaction without further purification.

References

[1] Patent: US2008/39457, 2008, A1. Location in patent: Page/Page column 41
[2] Patent: WO2008/64157, 2008, A1. Location in patent: Page/Page column 42-43
[3] Patent: US2009/291956, 2009, A1. Location in patent: Page/Page column 19
[4] Patent: US2011/212967, 2011, A1. Location in patent: Page/Page column 8
[5] Patent: WO2012/48421, 2012, A1. Location in patent: Page/Page column 24

3-Fluoro-4-bromo-acetophenone Preparation Products And Raw materials

Raw materials

Methylmagnesium Bromide Methylmagnesium chloride 4-Bromo-3-fluoro-N-methoxy-N-methyl-benzamide

Preparation Products

2-bromo-1-(4-bromo-3-fluorophenyl)ethanone

3-Fluoro-4-bromo-acetophenone Suppliers

Global Suppliers ( 141)
Supplier Tel Email Country ProdList Advantage
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Changzhou Huanling Chemical Co., Ltd. 89803005 18206112582 info@huanlingchem.com China 983 68
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Wuhan Haizheng Industry & Trade Development Co. Ltd 027-8866 0053/88660577/88660578 China 1070 55
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Supplier Advantage
Alfa Aesar 84
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Changzhou Huanling Chemical Co., Ltd. 68
Tetranov Biopharm 64
Shandong Xiya Chemical Co., Ltd 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Wuhan Haizheng Industry & Trade Development Co. Ltd 55
Tianjin Jinyuda Chemical Co., Ltd. 55
Hangzhou Sage Chemical Co., Ltd. 58

View Latest Price from 3-Fluoro-4-bromo-acetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-FLUORO-4-BROMO-ACETOPHENONE pictures 2019-07-06 3-FLUORO-4-BROMO-ACETOPHENONE
304445-49-6
 $1.00 1KG 95% 500KG Career Henan Chemical Co

3-Fluoro-4-bromo-acetophenone Spectrum

3-FLUORO-4-BROMO-ACETOPHENONE(304445-49-6)1HNMR3-FLUORO-4-BROMO-ACETOPHENONE(304445-49-6)FT-IR

304445-49-6 (3-Fluoro-4-bromo-acetophenone) Related Search:

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4-BROMO-3-FLUORO-ACETOPHENONE 6-acetyl-3-bromo-2-fluoro-1-cyclohexa-2,4-dienone 1-(4-BroMo-3-fluorophenyl)ethanone Ethanone, 1-(4-broMo-3-fluorophenyl)- 3-Fluoro-4-bromo-caetophenone 4-Bromo-3-fluoroacetophenone,96% 3-Fluoro-4-bromoacetopheone 4'-Bromo-3'-fluoroacetophenone 1-(4-broMo-3-fluorophenyl)ethan-1-one 3-Fluoro-4-bromo-acetophenone 304445-49-6