3,5-Dibromophenol
- CAS No.
- 626-41-5
- Chemical Name:
- 3,5-Dibromophenol
- Synonyms
- 3,5-Dlbromophenol;3,5-Dibromophenol;3,5-Dibromophenol>Phenol, 3,5-dibroMo-;3 5-DIBROMOPHENOL 97;3,5-Dibromophenol 98%;Phloroglucinol Impurity 15;3,5-Dibromophenol pure, 98%;3,5-Dibromophenol@100 μg/mL in Toluene
- CBNumber:
- CB6500148
- Molecular Formula:
- C6H4Br2O
- Molecular Weight:
- 251.9
- MDL Number:
- MFCD06411376
- MOL File:
- 626-41-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 79-83 °C (lit.) |
|---|---|
| Boiling point | 122°C/3mmHg(lit.) |
| Density | 1.8854 (rough estimate) |
| refractive index | 1.5380 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | pK1:8.056 (25°C) |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| Water Solubility | Sightly soluble in water. Soluble in methanol. |
| InChI | 1S/C6H4Br2O/c7-4-1-5(8)3-6(9)2-4/h1-3,9H |
| InChIKey | PZFMWYNHJFZBPO-UHFFFAOYSA-N |
| SMILES | Oc1cc(Br)cc(Br)c1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29081990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3,5-Dibromophenol price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 646105 | 3,5-Dibromophenol 97% | 626-41-5 | 1g | $50.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 646105 | 3,5-Dibromophenol 97% | 626-41-5 | 10g | $429 | 2026-04-30 | Buy |
| TCI Chemical | D3820 | 3,5-Dibromophenol >98.0%(GC) | 626-41-5 | 1g | $22 | 2026-04-30 | Buy |
| TCI Chemical | D3820 | 3,5-Dibromophenol >98.0%(GC) | 626-41-5 | 5g | $76 | 2026-04-30 | Buy |
| ChemScene | CS-W007905 | 3,5-Dibromophenol ≥98% | 626-41-5 | 5g | $14 | 2026-06-04 | Buy |
3,5-Dibromophenol Chemical Properties,Uses,Production
Chemical Properties
White to brown solid
Uses
3,5-Dibromophenol is used as a pharmaceutical intermediate. It is also used to prepare aromatic polyesters and drugs for arthritis.
Synthesis
74137-36-3
626-41-5
General procedure for the synthesis of 3,5-dibromophenol from 3,5-dibromoanisole: 3,5-dibromoanisole (15.57 g, 58.5 mmol) and tetrabutylammonium bromide (1.0 g, 3.1 mmol) were suspended in 48% hydrobromic acid solution (100 mL), and heated to reflux for 3 days. After the reaction was completed, it was cooled to room temperature and the reaction mixture was extracted with dichloromethane (3 x 60 mL). The organic layers were combined, washed with water, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/heptane, 10:1, v/v). After removal of the solvent, 14.23 g (97% yield) of 3,5-dibromophenol was obtained as light brown needle-like crystals.
References
[1] Journal of Organic Chemistry, 2004, vol. 69, # 25, p. 8982 - 8983
[2] Patent: US2006/270686, 2006, A1. Location in patent: Page/Page column 35
[3] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 179 - 200
[4] Patent: US2008/280891, 2008, A1. Location in patent: Page/Page column 35
[5] Patent: WO2008/8059, 2008, A1. Location in patent: Page/Page column 96
3,5-Dibromophenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhuhai Aobokai Biomedical Technology Co., Ltd. | 400-0628126 | sales-team@aobchem.com.cn | China | 49995 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
View Lastest Price from 3,5-Dibromophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3,5-Dibromophenol
626-41-5
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2019-07-06 | 3,5-Dibromophenol
626-41-5
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 3,5-Dibromophenol
626-41-5
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3,5-Dibromophenol
626-41-5
- $1.00
- 99%
- Career Henan Chemical Co
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