3,5-Dibromoanisole
- CAS No.
- 74137-36-3
- Chemical Name:
- 3,5-Dibromoanisole
- Synonyms
- 1,3-dibromo-5-methoxybenzene;3,5-DibromoanisoL;3,5-DIBROMOANISOLE;3,5-Dibromoanisole>3,5-Dibromobenzyl ether;3,5-dibromophenyl ether;Phloroglucinol Impurity 13;Benzene,1,3-dibroMo-5-Methoxy-
- CBNumber:
- CB7511635
- Molecular Formula:
- C7H6Br2O
- Molecular Weight:
- 265.93
- MDL Number:
- MFCD02258848
- MOL File:
- 74137-36-3.mol
- MSDS File:
- SDS
| Melting point | 34-38 °C |
|---|---|
| Boiling point | 249.7°C |
| Density | 1.823 |
| Flash point | 98.1°C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | White to Gray to Brown |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChI | InChI=1S/C7H6Br2O/c1-10-7-3-5(8)2-6(9)4-7/h2-4H,1H3 |
| InChIKey | OQZAQBGJENJMHT-UHFFFAOYSA-N |
| SMILES | C1(Br)=CC(OC)=CC(Br)=C1 |
| CAS DataBase Reference | 74137-36-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
3,5-Dibromoanisole price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 675830 | 3,5-Dibromoanisole 97% | 74137-36-3 | 1g | $78.3 | 2026-04-30 | Buy |
| TCI Chemical | D3364 | 3,5-Dibromoanisole >98.0%(GC) | 74137-36-3 | 5g | $44 | 2026-04-30 | Buy |
| TCI Chemical | D3364 | 3,5-Dibromoanisole >98.0%(GC) | 74137-36-3 | 25g | $170 | 2026-04-30 | Buy |
| Activate Scientific | AS25464 | 3,5-Dibromoanisole 98% | 74137-36-3 | 5g | $18 | 2026-06-04 | Buy |
| Apolloscientific | OR42208 | 3,5-Dibromoanisole 97% | 74137-36-3 | 1g | $21 | 2026-06-04 | Buy |
3,5-Dibromoanisole Chemical Properties, Uses, Production
Chemical Properties
solid
Uses
3,5-Dibromoanisole, is an organic building block used for the synthesis of various pharmaceutical compounds, such as Dicationic m-Terphenyl and 1,3-Dipyridylbenzene Derivatives, having Antiprotozoal Activity.
Synthesis
67-56-1
6311-60-0
74137-36-3
The general procedure for the synthesis of 3,5-dibromoanisole from methanol and 1,3-dibromo-5-nitrobenzene was as follows: 1,3-dibromo-5-nitrobenzene (21.07 g, 75 mmol), freshly powdered potassium hydroxide (7.57 g, 135 mmol) and tetrabutyl ammonium bromide (2.42 g, 7.5 mmol) were suspended in tetramethylurea (80 mL). A solution of methanol (4.81 g, 6.09 mL, 150 mmol) dissolved in 20 mL of tetramethylurea was added slowly and dropwise to the above brown suspension over a period of 15 min at room temperature. The reaction mixture was stirred continuously for 24 h at room temperature before it was quenched by pouring it into ice (150 g) and extracted with tert-butyl methyl ether (3 x 250 mL). The organic phases were combined, dried with magnesium sulfate and subsequently concentrated under reduced pressure to give the crude product. The crude product was purified by reduced pressure distillation (124 °C, 10 Torr) to give 16.74 g (84% yield) of 3,5-dibromoanisole as a light yellow solid.
References
[1] Patent: US2006/270686, 2006, A1. Location in patent: Page/Page column 35
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 179 - 200
[3] Patent: US2008/280891, 2008, A1. Location in patent: Page/Page column 34-35
[4] Patent: WO2008/8059, 2008, A1. Location in patent: Page/Page column 96
3,5-Dibromoanisole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Nantong Xiaochang Pharmaceutical Trading Co., Ltd. | 0513-82104991 15152894157 | sales11@btcpharm.com | China | 860 | 58 |
| Hubei Moco Chemical Co., Ltd. | 18627753421; 18627756402 | 3001051413@qq.com | China | 20013 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Latest Price from 3,5-Dibromoanisole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | 3,5-Dibromoanisole
74137-36-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 3,5-Dibromoanisole
74137-36-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-12-26 | 3,5-Dibromoanisole
74137-36-3
|
$1.00 | 1KG | 99% | 500kg | Career Henan Chemical Co |
-
- 3,5-Dibromoanisole
74137-36-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3,5-Dibromoanisole
74137-36-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3,5-Dibromoanisole
74137-36-3
- $1.00
- 99%
- Career Henan Chemical Co
