2-Bromo-4-nitrobenzoic acid
- CAS No.
- 16426-64-5
- Chemical Name:
- 2-Bromo-4-nitrobenzoic acid
- Synonyms
- NSC 227965;Metoclopramide Impurity 104;3-Bromo-4-carboxynitrobenzene;BENZOIC ACID, 2-BROMO-4-NITRO;2-Bromo-4-nitrobenzoic Acid >2-Bromo-4-nitrobenzoic acid 98%
- CBNumber:
- CB6501453
- Molecular Formula:
- C7H4BrNO4
- Molecular Weight:
- 246.01
- MDL Number:
- MFCD00234252
- MOL File:
- 16426-64-5.mol
- MSDS File:
- SDS
| Melting point | 165-168°C |
|---|---|
| Boiling point | 381.6±32.0 °C(Predicted) |
| Density | 2.0176 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 1.98±0.13(Predicted) |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| InChI | InChI=1S/C7H4BrNO4/c8-6-3-4(9(12)13)1-2-5(6)7(10)11/h1-3H,(H,10,11) |
| InChIKey | CEXGTXNIIFSPSF-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C([N+]([O-])=O)C=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2916399090 | |||||||||
| NFPA 704 |
|
2-Bromo-4-nitrobenzoic acid price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3607 | 2-Bromo-4-nitrobenzoic Acid >98.0%(GC)(T) | 16426-64-5 | 5g | $36 | 2026-04-30 | Buy |
| TCI Chemical | B3607 | 2-Bromo-4-nitrobenzoic Acid >98.0%(GC)(T) | 16426-64-5 | 25g | $154 | 2026-04-30 | Buy |
| TRC | TRC-B686215-5G | 2-Bromo-4-nitrobenzoic Acid | 16426-64-5 | 5g | $186 | 2026-06-03 | Buy |
| TRC | TRC-B686215-25G | 2-Bromo-4-nitrobenzoic Acid | 16426-64-5 | 25g | $485 | 2026-06-03 | Buy |
| TRC | TRC-B686215-10G | 2-Bromo-4-nitrobenzoic Acid | 16426-64-5 | 10g | $345 | 2026-06-03 | Buy |
2-Bromo-4-nitrobenzoic acid Chemical Properties, Uses, Production
Chemical Properties
Light Brown Solid
Synthesis
7745-93-9
16426-64-5
(a) Synthesis of 2-bromo-4-nitrobenzoic acid: 40 mL of water was added to 20 mL of pyridine solution containing 2-bromo-4-nitrotoluene (4.41 g, 20.0 mmol), and the mixture was heated to 70°C. Potassium permanganate (19.0 g, 120 mmol) was added batchwise over a 40-minute period, and the reaction mixture was subsequently refluxed for 8 hours. After completion of the reaction, the resulting suspension was thermally filtered. The filtrate was acidified with 6N hydrochloric acid to pH<2 under ice bath cooling, precipitated as a solid and filtered to give crude 2-bromo-4-nitrobenzoic acid (1.63 g). The filtrates were combined, the pH was adjusted to acidic with 6N hydrochloric acid and extracted with ethyl acetate and chloroform sequentially. The organic phases were combined, dried over anhydrous magnesium sulfate and filtered, and the filtrate was concentrated under reduced pressure to give the second batch of product (1.61 g). The total mass of the two batches of product was 3.24 g and the yield was 66%.
References
[1] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 12, p. 3011 - 3024
[2] Organic and Biomolecular Chemistry, 2006, vol. 4, # 3, p. 482 - 492
[3] Angewandte Chemie - International Edition, 2008, vol. 47, # 17, p. 3184 - 3187
[4] Chinese Chemical Letters, 2011, vol. 22, # 12, p. 1411 - 1414
[5] European Journal of Medicinal Chemistry, 2014, vol. 81, p. 59 - 75
2-Bromo-4-nitrobenzoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiaxing Deyi Chemical Co., Ltd. | 86-0573-85866609 18367600069 | 945717149@qq.com | China | 9507 | 58 |
| Xinyi Kangda Biological Technology Co., Ltd. | 16503038585 | xinyikangda@163.com | China | 610 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from 2-Bromo-4-nitrobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | 2-BROMO-4-NITROBENZOIC ACID
16426-64-5
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 2-BROMO-4-NITROBENZOIC ACID
16426-64-5
- $1.00
- 99%
- Career Henan Chemical Co
