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AZD-3458

CAS No.
2132961-46-5
Chemical Name:
AZD-3458
Synonyms
AZD-3458;AZD3458,AZD-3458;PI3Kγ inhibitor 3;N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl] acetamide;Acetamide, N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl]-
CBNumber:
CB65477386
Molecular Formula:
C20H23N3O4S2
Molecular Weight:
433.54
MDL Number:
MFCD31813677
MOL File:
2132961-46-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

AZD-3458 Properties

storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (576.65 mM; Need ultrasonic)
form Solid
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

AZD-3458 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 42104 AZD 3458 ≥98% 2132961-46-5 1mg $83 2026-04-30 Buy
Cayman Chemical 42104 AZD 3458 ≥98% 2132961-46-5 5mg $269 2026-04-30 Buy
Cayman Chemical 42104 AZD 3458 ≥98% 2132961-46-5 10mg $455 2026-04-30 Buy
Cayman Chemical 42104 AZD 3458 ≥98% 2132961-46-5 25mg $929 2026-04-30 Buy
ChemScene CS-0046065 AZD3458 99.71% 2132961-46-5 5mg $271 2026-06-04 Buy
Product number Packaging Price Buy
42104 1mg $83 Buy
42104 5mg $269 Buy
42104 10mg $455 Buy
42104 25mg $929 Buy
CS-0046065 5mg $271 Buy

AZD-3458 Chemical Properties,Uses,Production

Uses

N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl] acetamide is used in the preparation of Phosphoinositide 3-Kinase inhibitors.

IC 50

PI3Kγ: 9.1 (pIC50); PI3Kα: 5.1 (pIC50); PI3Kβ: 4.5 (pIC50); PI3Kδ: 6.5 (pIC50); PI3KC2α: 5 (pIC50); PI3KC2β: 7.5 (pIC50); PI3KC2γ: 5.5 (pIC50); PI3KC3: 5.1 (pIC50)

AZD-3458 Preparation Products And Raw materials

Raw materials

Preparation Products

AZD-3458 Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5987 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
Hubei Chuchang Chemical Co., Ltd 18 15623560702 info@chuchangbiotech.com China 190 58

View Lastest Price from AZD-3458 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AZD3458 pictures 2026-07-27 AZD3458
2132961-46-5
$970.00-2190.00 10g TargetMol Chemicals Inc.
AZD3458 pictures 2026-04-20 AZD3458
2132961-46-5
$970.00-2190.00 10g TargetMol Chemicals Inc.
AZD3458 pictures 2025-07-17 AZD3458
2132961-46-5
$970.00-2190.00 10g TargetMol Chemicals Inc.
  • AZD3458 pictures
  • AZD3458
    2132961-46-5
  • $970.00-2190.00
  • TargetMol Chemicals Inc.
  • AZD3458 pictures
  • AZD3458
    2132961-46-5
  • $970.00-2190.00
  • TargetMol Chemicals Inc.
  • AZD3458 pictures
  • AZD3458
    2132961-46-5
  • $970.00-2190.00
  • TargetMol Chemicals Inc.
AZD-3458 Acetamide, N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl]- N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl] acetamide AZD3458,AZD-3458 PI3Kγ inhibitor 3 2132961-46-5