ChemicalBook >> CAS DataBase List >>Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- structure

CAS No.: 1383376-92-8

Chemical Name:: Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-

Synonyms: CK1-IN-2;PF-05251749（CK1-IN-2）;4-[3-(4-Fluorophenyl)-1-methyl-1H-pyrazol-4-yl]furo[3,4-b]pyridin-5(7H)-one;Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-

CBNumber:: CB65481897

Molecular Formula:: C17H12FN3O2

Molecular Weight:: 309.29

MDL Number:

MOL File:: 1383376-92-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

Request For Quotation

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Properties

Boiling point	509.7±50.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
pka	0.89±0.20(Predicted)
form	Solid
color	Off-white to light yellow
InChI	InChI=1S/C17H12FN3O2/c1-21-8-13(16(20-21)10-2-4-11(18)5-3-10)12-6-7-19-14-9-23-17(22)15(12)14/h2-8H,9H2,1H3
InChIKey	XISSYJGQGSMWHO-UHFFFAOYSA-N
SMILES	C12COC(=O)C1=C(C1=CN(C)N=C1C1=CC=C(F)C=C1)C=CN=2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0865765	CK1-IN-2 99.20%	1383376-92-8	5mg	$219	2026-06-04	Buy
ChemScene	CS-0865765	CK1-IN-2 99.20%	1383376-92-8	10mg	$354	2026-06-04	Buy
ChemScene	CS-0865765	CK1-IN-2 99.20%	1383376-92-8	25mg	$536	2026-06-04	Buy
ChemScene	CS-0865765	CK1-IN-2 99.20%	1383376-92-8	50mg	$747	2026-06-04	Buy
ChemScene	CS-0865765	CK1-IN-2 99.20%	1383376-92-8	100mg	$1051	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0865765	5mg	$219	Buy
CS-0865765	10mg	$354	Buy
CS-0865765	25mg	$536	Buy
CS-0865765	50mg	$747	Buy
CS-0865765	100mg	$1051	Buy

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Chemical Properties, Uses, Production

Uses

CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].

IC 50

CKIα: 123 nM (IC₅₀)

References

[1] Joris De Maeyer, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717A1.

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Suppliers

Global Suppliers ( 13)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Haozhixiang Biotechnology Co., Ltd	526763801 13301653310	526763801@qq.com	China	7982	55
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9699	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	4565	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	5985	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Henan Yinuokai New Materials Co., Ltd	15565215982 15565215982	15565215982@163.com	China	3744	58
Shanghai Weijiahe Biotechnology Co., Ltd	17502176150; 17502176150	861873257@qq.com	China	2672	58
Shanghai Yaoheping Biopharmaceutical Technology Co., Ltd	57540919 13120888836	lily@yhp-biomedicine.com	China	9246	58
Jinan Hergy Biomedical Technology Co., Ltd.，	19285513406	hyqt2011@126.com	China	161	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32997	60

Supplier	Advantage
Shanghai Haozhixiang Biotechnology Co., Ltd	55
Shanghai Chaolan Chemical Technology Center	58
ShangHai ChuanQian Chemcial Technique Centre	58
Nantong QuanYi Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58
Henan Yinuokai New Materials Co., Ltd	58
Shanghai Weijiahe Biotechnology Co., Ltd	58
Shanghai Yaoheping Biopharmaceutical Technology Co., Ltd	58
Jinan Hergy Biomedical Technology Co., Ltd.，	58
ATK CHEMICAL COMPANY LIMITED	60

View Latest Price from Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-27	CK1-IN-2 1383376-92-8	$68.00-269.00		99.31%	10g	TargetMol Chemicals Inc.

CK1-IN-2
1383376-92-8
$68.00-269.00
99.31%
TargetMol Chemicals Inc.

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- Spectrum

Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-(1383376-92-8)¹HNMR

1383376-92-8 (Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-) Related Search:

1H-Pyrazole-4-carboxylic acid, 1-methyl-3-(3-pyridinyl)-, methyl ester Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- 1H-Pyrazole-4-carboxylic acid, 1-methyl-3-(4-pyridinyl)-, methyl ester CK1-IN-2 hydrochloride SR 3029

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Furo[3,4-b]pyridin-5(7H)-one, 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]- PF-05251749（CK1-IN-2） CK1-IN-2 4-[3-(4-Fluorophenyl)-1-methyl-1H-pyrazol-4-yl]furo[3,4-b]pyridin-5(7H)-one 1383376-92-8