4-Chloro-3-fluorobenzyl Bromide
- CAS No.
- 206362-80-3
- Chemical Name:
- 4-Chloro-3-fluorobenzyl Bromide
- Synonyms
- 4-(bromomethyl)-1-chloro-2-fluorobenzene;CAS:206362-80-3;4-CHLORO-3-FLUOROBENZYL BROMIDE;4-Chloro-3-fluorobenzylbromide97%;4-Chloro-3-fluorobenzyl Bromide >4-Chloro-3-fluorobenzyl bromide 97%;alpha-Bromo-4-chloro-3-fluorotoluene;1-(Bromomethyl)-4-chloro-3-fluorobenzene;REF DUPL: 4-Chloro-3-fluorobenzyl bromide;Benzene, 4-(bromomethyl)-1-chloro-2-fluoro-
- CBNumber:
- CB6654049
- Molecular Formula:
- C7H5BrClF
- Molecular Weight:
- 223.47
- MDL Number:
- MFCD04115859
- MOL File:
- 206362-80-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 30-33℃ |
|---|---|
| Boiling point | 227.1±25.0 °C(Predicted) |
| Density | 1.654±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to lump |
| color | White to Light yellow to Light orange |
| Sensitive | Lachrymatory |
| InChI | 1S/C7H5BrClF/c8-4-5-1-2-6(9)7(10)3-5/h1-3H,4H2 |
| InChIKey | CNUYBEIHDWMLSD-UHFFFAOYSA-N |
| SMILES | Fc1cc(CBr)ccc1Cl |
| CAS DataBase Reference | 206362-80-3(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H290-H314-H318 | |||||||||
| Precautionary statements | P305+P351+P338-P309-P310-P234-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P405-P406-P501 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 3261 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Hazard Note | Corrosive/Lachrymatory | |||||||||
| HazardClass | CORROSIVE | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | Ⅱ | |||||||||
| HS Code | 29039990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
4-Chloro-3-fluorobenzyl Bromide price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2484 | 4-Chloro-3-fluorobenzyl Bromide >98.0%(GC)(T) | 206362-80-3 | 1g | $23 | 2026-04-30 | Buy |
| TCI Chemical | C2484 | 4-Chloro-3-fluorobenzyl Bromide >98.0%(GC)(T) | 206362-80-3 | 5g | $69 | 2026-04-30 | Buy |
| Apolloscientific | PC9381 | 4-Chloro-3-fluorobenzyl bromide 97% | 206362-80-3 | 5g | $41 | 2026-06-04 | Buy |
| Apolloscientific | PC9381 | 4-Chloro-3-fluorobenzyl bromide 97% | 206362-80-3 | 25g | $102 | 2026-06-04 | Buy |
| Apolloscientific | PC9381 | 4-Chloro-3-fluorobenzyl bromide 97% | 206362-80-3 | 100g | $320 | 2026-06-04 | Buy |
4-Chloro-3-fluorobenzyl Bromide Chemical Properties, Uses, Production
Chemical Properties
White solid
Synthesis
202925-10-8
206362-80-3
Step 1: Bromine (16.5 g, 0.103 mol) was added dropwise to a solution of triphenylphosphine (27.8 g, 0.103 mol) in dichloromethane (200 mL) at 0°C while stirring. After the dropwise addition was completed, stirring of the reaction mixture was continued for 10 minutes. Subsequently, 4-chloro-3-fluorobenzyl alcohol (15.8 g, 0.098 mol) was added and the reaction mixture was stirred for 30 minutes. Upon completion of the reaction, the reaction was quenched with ethanol and the mixture was poured into saturated sodium bicarbonate solution and extracted with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated. Purification by silica gel column chromatography afforded 4-(bromomethyl)-1-chloro-2-fluorobenzene (18.6 g, 85% yield).1H-NMR (400 MHz, CDCl3): δ = 7.27 (t, J = 7.9 Hz, 1H), 7.10 (dd, J = 7.9 Hz, 2.1 Hz, 1H), 7.04-6.99 (m, 1H). 4.32 (s, 2H).
References
[1] Patent: EP2952510, 2015, A1. Location in patent: Paragraph 0185
4-Chloro-3-fluorobenzyl Bromide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Latest Price from 4-Chloro-3-fluorobenzyl Bromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 4-CHLORO-3-FLUOROBENZYL BROMIDE
206362-80-3
|
$1.00 | 1KG | 98% HPLC | 10 tons/month | Career Henan Chemical Co |
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- 4-CHLORO-3-FLUOROBENZYL BROMIDE
206362-80-3
- $1.00
- 98% HPLC
- Career Henan Chemical Co
