Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid
- CAS No.
- 334932-13-7
- Chemical Name:
- Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid
- Synonyms
- 3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylic acid;BOC-1,3-CIS-ACHC-OH;3-(BOC-AMINO)CYCLOHEXANECARBOXYLIC ACID;BOC-CIS-3-AMINOCYCLOHEXANE CARBOXYLIC ACID;BOC-CIS-1,3-AMINOCYCLOHEXANE CARBOXYLIC ACID;3-(Boc-amino)cyclohexanecarboxylic acid 97%;3-(Boc-aMino)cyclohexanecarboxylic acid, 98+%;N-BOC-cis-3-Aminocyclohexane-1-carboxylic acid;Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid;CIS-3-TERT-BUTOXYCARBONYLAMINOCYCLOHEXANECARBOXYLIC ACID
- CBNumber:
- CB6668929
- Molecular Formula:
- C12H21NO4
- Molecular Weight:
- 243.3
- MDL Number:
- MFCD03453252
- MOL File:
- 334932-13-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2924297099 | |||||||||
| NFPA 704 |
|
Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 266945 | 3-(Boc-amino)cyclohexanecarboxylic acid Asreported | 334932-13-7 | 250mg | $319 | 2026-06-03 | Buy |
| Usbiological | 266945 | 3-(Boc-amino)cyclohexanecarboxylic acid Asreported | 334932-13-7 | 500mg | $439 | 2026-06-03 | Buy |
| Usbiological | 266945 | 3-(Boc-amino)cyclohexanecarboxylic acid Asreported | 334932-13-7 | 1g | $602 | 2026-06-03 | Buy |
| Usbiological | 266945 | 3-(Boc-amino)cyclohexanecarboxylic acid Asreported | 334932-13-7 | 2g | $744 | 2026-06-03 | Buy |
| Usbiological | 266945 | 3-(Boc-amino)cyclohexanecarboxylic acid Asreported | 334932-13-7 | 5g | $1097 | 2026-06-03 | Buy |
Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid Chemical Properties, Uses, Production
Uses
3-(Boc-amino)cyclohexanecarboxylic acid is used as pharmaceutical intermediate.
Synthesis
24424-99-5
16636-51-4
334932-13-7
Step 1: Synthesis of 3-(tert-butoxycarbonylamino)-1-cyclohexanecarboxylic acid; 1 N NaOH (41.9 mL, 105 mmol) was added to a suspension of cis-3-aminocyclohexanecarboxylic acid (10 g, 69.8 mmol) in 1,3-dioxane (100.0 mL). After stirring for 10 min, the mixture became a clarified solution followed by the addition of di-tert-butyl dicarbonate (21.08 mL, 91 mmol). The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the resulting solid was collected by vacuum filtration and then dissolved in water (150 mL). The aqueous phase was acidified to pH 4 with 3 N HCl and then extracted with dichloromethane (DCM, 2 × 100 mL). The organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4) and subsequently concentrated under reduced pressure to afford 3-(tert-butoxycarbonylamino)-1-cyclohexanecarboxylic acid as a white powder (17.0 g, 100% yield).
References
[1] Patent: WO2009/49157, 2009, A1. Location in patent: Page/Page column 53
[2] Patent: WO2008/75196, 2008, A1. Location in patent: Page/Page column 83
[3] Patent: WO2015/196071, A1. Location in patent: Paragraph 0634
[3] Patent: , 2015, . Location in patent: Paragraph 0634
[5] Patent: WO2017/40606, 2017, A1. Location in patent: Paragraph 0583
Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| YangZhou Ruihong Biotech Co., Ltd. | 0514-015380367604 15380367604 | sales@ruibobiotech.com | China | 509 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Beijing FYF Chemicals Co., Ltd | 010-57903446 15869909019 | 168931144@qq.com | China | 2876 | 58 |
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6959 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Hubei Jusheng Technology Co.,Ltd | 027-59599241 18871490274 | 1400878000@qq.com | China | 9506 | 58 |
View Latest Price from Boc-(+/-)-cis-3-aminocyclohexane-1-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 3-(Boc-amino)cyclohexanecarboxylic acid
334932-13-7
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2020-01-01 | BOC-(+/-)-CIS-3-AMINOCYCLOHEXANE-1-CARBOXYLIC ACID
334932-13-7
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- 3-(Boc-amino)cyclohexanecarboxylic acid
334932-13-7
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- BOC-(+/-)-CIS-3-AMINOCYCLOHEXANE-1-CARBOXYLIC ACID
334932-13-7
- $1.00
- 95-99%
- Career Henan Chemical Co
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