ChemicalBook >> CAS DataBase List >>(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride

(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride

CAS No.
148700-85-0
Chemical Name:
(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride
Synonyms
L 733060;L-733,060 hydrochlor;L-733,060 HYDROCHLORIDE;3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine;Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-;(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride
CBNumber:
CB6676120
Molecular Formula:
C20H19F6NO
Molecular Weight:
403.36
MDL Number:
MFCD05865535
MOL File:
148700-85-0.mol
Last updated:2026-09-12 18:54:21

(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Properties

storage temp. 2-8°C
solubility DMSO: >10 mg/mL
form solid
color white
FDA UNII PK8CG2B44U

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0013970 L-733060 95.00% 148700-85-0 250MG $349.65 2021-12-16 Buy
Product number Packaging Price Buy
API0013970 250MG $349.65 Buy

(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Chemical Properties, Uses, Production

Definition

ChEBI: (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine is a member of piperidines.

Biological Activity

A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant.

(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Suppliers

Global Suppliers ( 20)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25030 58
L-733,060 HYDROCHLORIDE 3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine L 733060 Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)- L-733,060 hydrochlor (2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride 148700-85-0 Tachykinin receptor