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| | (2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Basic information |
| Product Name: | (2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride | | Synonyms: | L-733,060 HYDROCHLORIDE;3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine;L 733060;Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-;L-733,060 hydrochlor;(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride | | CAS: | 148700-85-0 | | MF: | C20H19F6NO | | MW: | 403.36 | | EINECS: | | | Product Categories: | Tachykinin receptor | | Mol File: | 148700-85-0.mol | ![(2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Structure](CAS/GIF/148700-85-0.gif) |
| | (2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: >10 mg/mL | | form | solid | | color | white |
| | (2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Usage And Synthesis |
| Definition | ChEBI: (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine is a member of piperidines. | | Biological Activity | A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant. |
| | (2S,3S)-3-[[3,5-Bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride Preparation Products And Raw materials |
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