3-Formylphenylboronic acid
- CAS No.
- 87199-16-4
- Chemical Name:
- 3-Formylphenylboronic acid
- Synonyms
- 3-FORMYLBORONIC ACID;3-FORMYLBENZENEBORONIC ACID;AURORA 15117;AKOS BRN-0110;ZERENEX ZX001648;IFLAB-BB F1371-0205;TIMTEC-BB SBB004078;RARECHEM AH PB 0194;3-BORONOBENZALDEHYDE;3-Formylphenylboroni
- CBNumber:
- CB6677374
- Molecular Formula:
- C7H7BO3
- Molecular Weight:
- 149.94
- MDL Number:
- MFCD00161356
- MOL File:
- 87199-16-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 109-113 °C |
|---|---|
| Boiling point | 354.4±44.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | soluble in Methanol |
| pka | 7.83±0.10(Predicted) |
| form | Powder, Crystals, and/or Chunks |
| color | Off-white to beige or light orange |
| Sensitive | Air Sensitive |
| BRN | 3030769 |
| InChI | InChI=1S/C7H7BO3/c9-5-6-2-1-3-7(4-6)8(10)11/h1-5,10-11H |
| InChIKey | HJBGZJMKTOMQRR-UHFFFAOYSA-N |
| SMILES | B(C1=CC=CC(C=O)=C1)(O)O |
| CAS DataBase Reference | 87199-16-4(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 34-36/37/38 | |||||||||
| Safety Statements | 22-26-36/37/39-45-37/39-27 | |||||||||
| RIDADR | UN 3261 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, MOISTURE SENSITIVE | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3-Formylphenylboronic acid price More Price(94)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 441651 | 3-Formylphenylboronic acid ≥95% | 87199-16-4 | 5g | $38.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 441651 | 3-Formylphenylboronic acid ≥95% | 87199-16-4 | 25g | $72.8 | 2026-04-30 | Buy |
| TCI Chemical | F0445 | 3-Formylphenylboronic Acid (contains varying amounts of Anhydride) | 87199-16-4 | 1g | $24 | 2026-04-30 | Buy |
| TCI Chemical | F0445 | 3-Formylphenylboronic Acid (contains varying amounts of Anhydride) | 87199-16-4 | 5g | $48 | 2026-04-30 | Buy |
| Usbiological | 276063 | 3-Formylphenylboronic acid Asreported | 87199-16-4 | 10g | $319 | 2026-06-03 | Buy |
3-Formylphenylboronic acid Chemical Properties,Uses,Production
Chemical Properties
Off-white Cryst
Uses
3-Formylphenylboronic acid can be used as reagent to study the effects of boronic acid on fluoride-selective chemosignaling behavior of merocyanine dye and as exciton-coupled CD probes for epigallocatechin gallate Biological inhibitor of γ-glutamyltranspeptidase.
Uses
suzuki reaction
Uses
Reagent used:
- To study the effects of boronic acid on fluoride-selective chemosignaling behavior of merocyanine dye
- As exciton-coupled CD probes for epigallocatechin gallate
Biological inhibitor of γ-glutamyltranspeptidase
Reactant involved in:
- Palladium-catalyzed homocoupling
- Suzuki coupling reactions
Synthesis
![Magnesium, bromo[3-(dimethoxymethyl)phenyl]-](/CAS/20211123/GIF/540777-53-5.gif)
540777-53-5
121-43-7
87199-16-4
The general procedure for the synthesis of 3-formylphenylboronic acid from the compound (CAS:540777-53-5) and trimethyl borate was carried out as follows: firstly, a THF solution of trimethyl borate was prepared by adding 154.8 ml of trimethyl borate to a 3-liter three-necked flask, followed by 915 ml of tetrahydrofuran (THF). The solution was stirred under nitrogen protection and cooled with an ice bath. The cooled THF solution was slowly added to a 3-liter flask containing Grignard reagent through a stainless steel tube. The reaction mixture was stirred under ice bath cooling for 1 hour and then an aqueous sulfuric acid solution prepared from 30 ml of concentrated sulfuric acid and 480 ml of water was added. The temperature of the mixture was gradually brought to room temperature and stirring was continued at this temperature for 2 hours. After stopping stirring, the reaction mixture was allowed to stand at room temperature overnight. The precipitate was removed by filtration and the filtrate was concentrated. The concentrated residue was mixed with an equal volume of water and stirred at room temperature for 1 hour. The solid product was collected by filtration and dried to give 123.46 g of 3-formylphenylboronic acid in 88% yield. The 1H-NMR (200 MHz, CDCl3, δ ppm) data of the resulting product were as follows: 7.54 (t, J = 7.5 Hz, 1H), 7.93 (d, J = 6.1 Hz, 1H), 7.9-8.1 (br.d, 1H), 8.2-8.3 (br.s, 1H), 10.04 (s, 1H).
References
[1] BARTOSZ ZARYCHTA. 3-formylphenylboronic acid.[J]. Acta crystallographica. Section C, Crystal structure communications, 2004, 60 Pt 5: o344-5. DOI:10.1107/S0108270104006493.
[2] E. TANI. Conformational, Structural, Vibrational, Electronic, and Molecular Docking Studies of 3-Formylphenylboronic Acid and 4-Formylphenylboronic Acid: A Comparative Study[J]. Russian Journal of Physical Chemistry A, 2020, 94 13: 2784-2796. DOI:10.1134/S0036024420130282.
3-Formylphenylboronic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhenjiang Carbochem Pharmatech Co.,LTD | 0511-81886918 18136818960 | sales4@carbo-chem.com | China | 357 | 58 |
| Hebei Maison Chemical Co.,Ltd. | 155-11852758; 18408670720 | ruby@maisonchem.com.cn | China | 687 | 58 |
| Zhuhai Aobokai Biomedical Technology Co., Ltd. | 400-0628126 | sales-team@aobchem.com.cn | China | 49995 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Lastest Price from 3-Formylphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | 3-Formylphenylboronic acid
87199-16-4
|
$5.00 | 1kg | ≥99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2026-09-02 | 3-Formylphenylboronic acid
87199-16-4
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2021-08-13 | 3-Formylphenylboronic acid
87199-16-4
|
$40.00 | 1KG | 99 | 10 tons | Shijiazhuang tongyang Import and Export Co., LTD |
-
- 3-Formylphenylboronic acid
87199-16-4
- $5.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 3-Formylphenylboronic acid
87199-16-4
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-Formylphenylboronic acid
87199-16-4
- $40.00
- 99
- Shijiazhuang tongyang Import and Export Co., LTD
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