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2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE structure

CAS No.: 219138-24-6

Chemical Name:: 2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE

Synonyms: p38 MAPK Inhibitor;P38 MAP KINASE INHIBITOR;p-38 MAPK Inhibitor,p38 MAPK Inhibitor;p38 MAP Kinase Inhibitor, p38 MAPK inhibitor;2-(4-chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1H-pyrazol-3-one;2-(4-CHLOROPHENYL)-4-(FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE;2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE;2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,2-dihydro-3H-pyrazol-3-one;3H-Pyrazol-3-one, 2-(4-chlorophenyl)-4-(4-fluorophenyl)-1,2-dihydro-5-(4-pyridinyl)-

CBNumber:: CB6682024

Molecular Formula:: C20H13ClFN3O

Molecular Weight:: 365.79

MDL Number:: MFCD03452698

MOL File:: Mol file

Last updated:2025-08-21 22:16:43

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2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE Properties

Boiling point	534.1±60.0 °C(Predicted)
Density	1.388±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMF: 5 mg/ml; DMSO: 5 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 0.3 mg/ml
form	A crystalline solid
pka	6.61±0.10(Predicted)
color	Light yellow to yellow
UNSPSC Code	12352200

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	17650	p38 MAPK Inhibitor ≥98%	219138-24-6	500μg	$121	2024-03-01	Buy
Cayman Chemical	17650	p38 MAPK Inhibitor ≥98%	219138-24-6	1mg	$230	2024-03-01	Buy
Cayman Chemical	17650	p38 MAPK Inhibitor ≥98%	219138-24-6	5mg	$722	2024-03-01	Buy
AK Scientific	0527CA	p38MAPKinaseInhibitor	219138-24-6	5mg	$901	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000172	P-38 MAP KINASE INHIBITOR 95.00%	219138-24-6	1MG	$316.05	2021-12-16	Buy

Product number	Packaging	Price	Buy
17650	500μg	$121	Buy
17650	1mg	$230	Buy
17650	5mg	$722	Buy
0527CA	5mg	$901	Buy
KIN0000172	1MG	$316.05	Buy

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE Chemical Properties,Uses,Production

Uses

p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM[1].

Biological Activity

Cell permeable: no', 'Product does not compete with ATP.', 'Reversible: no

IC 50

p38: 35 nM (IC₅₀)

References

[1] S E de Laszlo, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94. DOI:10.1016/s0960-894x(98)00495-8

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE Suppliers

Global( 56)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32430	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	71826	60
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	6751	55
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
BOC Sciences	--	info@bocsci.com	USA	0	65
Shanghai Zeye Biotechnology Co., Ltd.	021-021-61998551 13122364865	sale1@shzysw.net	China	9778	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Hefei Mokai Pharmaceutical Technology Co., Ltd	18130062233	3362556465@qq.com	China	8100	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62320	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Shanghai Hongye Biotechnology Co. Ltd	58
BOC Sciences	65
Shanghai Zeye Biotechnology Co., Ltd.	58
MedBioPharmaceutical Technology Inc	58
Hefei Mokai Pharmaceutical Technology Co., Ltd	58
Bide Pharmatech Ltd.	58

View Lastest Price from 2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-08-21	p38 MAPK Inhibitor 219138-24-6	US $88.00-483.00 / mg		99.24%	10g	TargetMol Chemicals Inc.

p38 MAPK Inhibitor
219138-24-6
US $88.00-483.00 / mg
99.24%
TargetMol Chemicals Inc.

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE Spectrum

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE(219138-24-6)¹HNMR

219138-24-6(2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE)Related Search:

P38 Mapk Inhibitor

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE 2-(4-CHLOROPHENYL)-4-(FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE P38 MAP KINASE INHIBITOR 2-(4-chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1H-pyrazol-3-one p38 MAPK Inhibitor p-38 MAPK Inhibitor,p38 MAPK Inhibitor 3H-Pyrazol-3-one, 2-(4-chlorophenyl)-4-(4-fluorophenyl)-1,2-dihydro-5-(4-pyridinyl)- 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,2-dihydro-3H-pyrazol-3-one p38 MAP Kinase Inhibitor, p38 MAPK inhibitor 219138-24-6