3-Hydroxypropionic acid
- CAS No.
- 503-66-2
- Chemical Name:
- 3-Hydroxypropionic acid
- Synonyms
- 3-HYDROXYPROPANOIC ACID;HYDRACRYLIC ACID;Propanoic acid, 3-hydroxy-;CHEBI:33404;beta-lacticacid;.beta.-Lacticacid;ethylenelacticacid;2-deoxy-glycericaci;RARECHEM AL BO 0193;2-deoxy-Glycericacid
- CBNumber:
- CB6711580
- Molecular Formula:
- C3H6O3
- Molecular Weight:
- 90.08
- MDL Number:
- MFCD00058998
- MOL File:
- 503-66-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 16.8°C (estimate) |
|---|---|
| Boiling point | 212°C (rough estimate) |
| Density | 1.066 g/mL at 25 °C |
| refractive index | 1.4489 |
| Flash point | >110° |
| storage temp. | 2-8°C |
| solubility | Ethanol, Methanol, Water |
| form | Colourless Solution |
| pka | 4.51(at 25℃) |
| color | Colorless to Almost colorless |
| Water Solubility | 270.1g/L(25 ºC) |
| Cosmetics Ingredients Functions | SKIN CONDITIONING - MISCELLANEOUS |
| InChI | InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6) |
| InChIKey | ALRHLSYJTWAHJZ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCO |
| CAS DataBase Reference | 503-66-2(CAS DataBase Reference) |
| FDA UNII | C4ZF6XLD2X |
| UNSPSC Code | 12352200 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-41-37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-39 | |||||||||
| WGK Germany | WGK 1 | |||||||||
| HS Code | 29181990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-Hydroxypropionic acid price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 792659 | 3-Hydroxypropionic acid, 30%solution in water | 503-66-2 | 1G | $70.1 | 2026-04-30 | Buy |
| TCI Chemical | H0297 | 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L) | 503-66-2 | 10g | $179 | 2026-04-30 | Buy |
| TCI Chemical | H0297 | 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L) | 503-66-2 | 25g | $369 | 2026-04-30 | Buy |
| Biosynth | FH31242 | 3-Hydroxypropanoic acid - 30% solution in water | 503-66-2 | 5g | $171.9 | 2026-06-04 | Buy |
| Biosynth | FH31242 | 3-Hydroxypropanoic acid - 30% solution in water | 503-66-2 | 10g | $275 | 2026-06-04 | Buy |
3-Hydroxypropionic acid Chemical Properties,Uses,Production
Description
3-Hydroxypropionic acid (3-HP) is considered as a potential building block either for organic synthesis or high performance polymers.It is a 3-carbon carboxylic acid, structural isomer of lactic acid, which naturally exists in some thermophilic archaea and bacteria. This organic compound has been pointed out by the US Department of Energy as a promising biomass derivate, which could potentially be used for the production of high added-value chemicals like1,3-propanediol, acrylic acid, acrylamide, and bioplastics.
Being 3-HP a commercially valuable, important platform chemical, researches have been conducted about its production on commercial scale, mainly from renewable sources. The biological production of 3-HP from glycerol and glucose, both based on microbial fermentation, are among the main routes studied. More specifically, research activities have been devoted to goals such as identifying novel biochemical pathways, metabolic engineering of microbial strains for the production of 3-HP, and improvements of cultivation techniques to increase 3-HP production titers.
Despite intense research efforts, there are still important bottlenecks for cost efficient, large scale biological production of 3-Hydroxypropionic Acid.
Chemical Properties
Syrupy substance. Easily soluble in water, ethanol and ether.
Uses
3-Hydroxypropionic Acid induces gene expressions and also functions as a reagent for industrial application.
Uses
A three carbon non-chiral compound, 3-Hydroxypropionic acid can be used as a building block for industrial chemicals.
Definition
ChEBI: A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group.
Production Methods
β-Hydroxypropionic acid can be prepared by alkaline hydration of acrylic acid or by treatment of ethylene chlorohydrin with sodium cyanide, followed by hydrolysis of the resulting β-hydroxypropionitrile. It is also readily obtained by hydrolysis of the commercially important and easily accessible compound β-propiolactone.
3-Hydroxypropionic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Yinuokai New Materials Co., Ltd | 15764055027 15764055027 | 15764055027@163.com | China | 539 | 58 |
| Zhongke Kangqirui (Dalian) Pharmaceutical Technology Co., Ltd | 15640952613 15640952613 | zhongkekangqirui@163.com | China | 158 | 58 |
| Nanbu County Chengxin Technology Co., Ltd. | 0838-5675166 15883665058 | nbcxkj@126.com | China | 956 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 3-Hydroxypropionic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-07 | 3-Hydroxypropionic acid
503-66-2
|
$1.00 | 1KG | 99%+ | 10000KG | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2025-04-04 | 3-Hydroxypropionic acid
503-66-2
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | ||
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2025-03-28 | 3-Hydroxypropionic acid
503-66-2
|
$6.00 | 1kg | More than 99% | 2000KG/Month | Hebei Longbang Technology Co., Ltd |
-

- 3-Hydroxypropionic acid
503-66-2
- $1.00
- 99%+
- Shaanxi Dideu Medichem Co. Ltd
-

- 3-Hydroxypropionic acid
503-66-2
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- 3-Hydroxypropionic acid
503-66-2
- $6.00
- More than 99%
- Hebei Longbang Technology Co., Ltd
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