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3-Hydroxypropionic acid

CAS No.
503-66-2
Chemical Name:
3-Hydroxypropionic acid
Synonyms
3-HYDROXYPROPANOIC ACID;HYDRACRYLIC ACID;Propanoic acid, 3-hydroxy-;CHEBI:33404;beta-lacticacid;.beta.-Lacticacid;ethylenelacticacid;2-deoxy-glycericaci;RARECHEM AL BO 0193;2-deoxy-Glycericacid
CBNumber:
CB6711580
Molecular Formula:
C3H6O3
Molecular Weight:
90.08
MDL Number:
MFCD00058998
MOL File:
503-66-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:10:41

3-Hydroxypropionic acid Properties

Melting point 16.8°C (estimate)
Boiling point 212°C (rough estimate)
Density 1.066 g/mL at 25 °C
refractive index 1.4489
Flash point >110°
storage temp. 2-8°C
solubility Ethanol, Methanol, Water
form Colourless Solution
pka 4.51(at 25℃)
color Colorless to Almost colorless
Water Solubility 270.1g/L(25 ºC)
Cosmetics Ingredients Functions SKIN CONDITIONING - MISCELLANEOUS
InChI InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6)
InChIKey ALRHLSYJTWAHJZ-UHFFFAOYSA-N
SMILES C(O)(=O)CCO
CAS DataBase Reference 503-66-2(CAS DataBase Reference)
FDA UNII C4ZF6XLD2X
UNSPSC Code 12352200
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
target organs Respiratory system
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-41-37/38-22
Safety Statements  26-36/37/39-39
WGK Germany  WGK 1
HS Code  29181990
Storage Class 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
NFPA 704
0
1 0

3-Hydroxypropionic acid price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 792659 3-Hydroxypropionic acid, 30%solution in water 503-66-2 1G $70.1 2026-04-30 Buy
TCI Chemical H0297 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L) 503-66-2 10g $179 2026-04-30 Buy
TCI Chemical H0297 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L) 503-66-2 25g $369 2026-04-30 Buy
Biosynth FH31242 3-Hydroxypropanoic acid - 30% solution in water 503-66-2 5g $171.9 2026-06-04 Buy
Biosynth FH31242 3-Hydroxypropanoic acid - 30% solution in water 503-66-2 10g $275 2026-06-04 Buy
Product number Packaging Price Buy
792659 1G $70.1 Buy
H0297 10g $179 Buy
H0297 25g $369 Buy
FH31242 5g $171.9 Buy
FH31242 10g $275 Buy

3-Hydroxypropionic acid Chemical Properties,Uses,Production

Description

3-Hydroxypropionic acid (3-HP) is considered as a potential building block either for organic synthesis or high performance polymers.It is a 3-carbon carboxylic acid, structural isomer of lactic acid, which naturally exists in some thermophilic archaea and bacteria. This organic compound has been pointed out by the US Department of Energy as a promising biomass derivate, which could potentially be used for the production of high added-value chemicals like1,3-propanediol, acrylic acid, acrylamide, and bioplastics.
Being 3-HP a commercially valuable, important platform chemical, researches have been conducted about its production on commercial scale, mainly from renewable sources. The biological production of 3-HP from glycerol and glucose, both based on microbial fermentation, are among the main routes studied. More specifically, research activities have been devoted to goals such as identifying novel biochemical pathways, metabolic engineering of microbial strains for the production of 3-HP, and improvements of cultivation techniques to increase 3-HP production titers.
Despite intense research efforts, there are still important bottlenecks for cost efficient, large scale biological production of 3-Hydroxypropionic Acid.

Chemical Properties

Syrupy substance. Easily soluble in water, ethanol and ether.

Uses

3-Hydroxypropionic Acid induces gene expressions and also functions as a reagent for industrial application.

Uses

A three carbon non-chiral compound, 3-Hydroxypropionic acid can be used as a building block for industrial chemicals.

Definition

ChEBI: A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group.

Production Methods

β-Hydroxypropionic acid can be prepared by alkaline hydration of acrylic acid or by treatment of ethylene chlorohydrin with sodium cyanide, followed by hydrolysis of the resulting β-hydroxypropionitrile. It is also readily obtained by hydrolysis of the commercially important and easily accessible compound β-propiolactone.

Global( 244)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Yinuokai New Materials Co., Ltd 15764055027 15764055027 15764055027@163.com China 539 58
Zhongke Kangqirui (Dalian) Pharmaceutical Technology Co., Ltd 15640952613 15640952613 zhongkekangqirui@163.com China 158 58
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66

View Lastest Price from 3-Hydroxypropionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Hydroxypropionic acid pictures 2026-08-07 3-Hydroxypropionic acid
503-66-2
$1.00 1KG 99%+ 10000KG Shaanxi Dideu Medichem Co. Ltd
3-Hydroxypropionic acid pictures 2025-04-04 3-Hydroxypropionic acid
503-66-2
1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
3-Hydroxypropionic acid pictures 2025-03-28 3-Hydroxypropionic acid
503-66-2
$6.00 1kg More than 99% 2000KG/Month Hebei Longbang Technology Co., Ltd
.beta.-Hydroxypropionicacid .beta.-Lacticacid beta-lacticacid ethylenelacticacid Glycericacid,2-deoxy- Hydracrylic-acid-ethylenelacticacid Propionicacid,3-hydroxy- β-Hydroxypropionsαure 3-HYDROXYPROPIONIC ACID RARECHEM AL BO 0193 2-deoxy-glycericaci 2-deoxy-Glycericacid 3-Hydroxypropansαure 3-Hydroxypropioicacid 3-hydroxy-propionicaci beta-hydroxypropionicacid 3-HYDROXYPROPIONIC ACID (BETA-)(CA. 30% IN WATER) 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L) 3-Hydrocypropanoic acid 3-Hydroxypropionicacid,30%inwater 3-HYDROXYPROPANOICACID(30%SOLUTIONINWATER) 3-Hydroxypropionic acid ,98% 3-Hydroxypropanoic acid, 30% aqueous solution (contains varying aMounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6Mol/L) 3-Hydroxypropionic Acid  3-Hydroxypropanoic acid 95% 3-Hydroxypropionic acid, Hydracrylic acid 3-Hydroxypropanoic acid solution 3-Hydroxypropionic Acid (ca. 30% in Water, ca. 3.6mol/L) CHEBI:33404 3-Hydroxypropanoic acid (30% in water) 3-Hydroxypropionic acid, 30% solution in H2O 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) 3-Hydroxypropinic acid 3-Hydroxypropionic Acid, Approx 30% in Water (with varying amounts of 3,3'-Oxydipropanoic Acid) Famotidine Impurity 18 "3-Hydroxypropionic acid, approx 30% in water" 3-Hydroxypropionic Acid, 30wt.% in H2O 3-Hydroxypropanoic acid(contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water) 3-Hydroxypropionic acid(ca. 30% in Water) 3-Hydroxypropionicacid,neat Famotidine Impurity 37 3-Hydroxypropanoic acid(contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water),ca. 30% in water 3-Hydroxypropionic Acid, in aq solution (with varying amounts of 3,3'-Oxydipropanoic Acid) 3-Hydroxypropionic acid (28%-32% in Water) 3-HYDROXYPROPANOIC ACID HYDRACRYLIC ACID Propanoic acid, 3-hydroxy- 503-66-2 HOCH2CH2COOH 蠅-Hydroxycarboxylic Acids 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides omega-Functional Alkanols, Carboxylic Acids, Amines & Halides omega-Hydroxycarboxylic Acids Carboxylic Acids Aliphatics Carboxylic Acids