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(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

CAS No.
88046-01-9
Chemical Name:
(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride
Synonyms
N-[4-[[(amino iminomethyl) thio]-methyl]-2-thiazolyl]-guanidine dihydrochloride (FMT-II);Famotidine Impurity 13;Iso Thiourea Hcl. (ITU);Famotidine Impurity H DiHCl;Famotidine EP Impurity H HCL;Famotidine Related Compound h;Famotidine EP Impurity H DiHCl;Famotidine Isothiourea Impurity;[2-[(Diaminomethylidene)amino]thiaz;Famotidine double salt intermediate
CBNumber:
CB3511561
Molecular Formula:
C6H11ClN6S2
Molecular Weight:
266.77
MDL Number:
MFCD01075760
MOL File:
88046-01-9.mol
MSDS File:
SDS
Last updated:2026-05-28 02:45:29

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Properties

Melting point >188oC (dec.)
storage temp. Refrigerator
solubility DMSO (Sparingly), Methanol (Slightly)
form Solid
color White to Off-White
PH 3.89 at 1000g/L
InChI InChI=1S/C6H10N6S2.ClH/c7-4(8)12-6-11-3(2-14-6)1-13-5(9)10;/h2H,1H2,(H3,9,10)(H4,7,8,11,12);1H
InChIKey DMXJVYCDETXZRR-UHFFFAOYSA-N
SMILES N(C1SC=C(CSC(N)=N)N=1)C(N)=N.Cl
LogP 1 at 30℃ and pH3.89
FDA UNII 3PZ8U72L9W

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H412-H302-H332-H402-H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501-P273-P501-P261-P271-P304+P340-P312
REACH Registrations Active

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-G835800-1G S-(2-Guanidino-4-thiazolyl)methylisothiourea Dihydrochloride 88046-01-9 1g $191 2026-06-03 Buy
TRC TRC-G835800-10G S-(2-Guanidino-4-thiazolyl)methylisothiourea Dihydrochloride 88046-01-9 10g $1438 2026-06-03 Buy
Biosynth FG23710 (S)-(2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 88046-01-9 100g $254 2026-06-04 Buy
Biosynth FG23710 (S)-(2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 88046-01-9 250g $390 2026-06-04 Buy
Biosynth FG23710 (S)-(2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 88046-01-9 500g $600 2026-06-04 Buy
Product number Packaging Price Buy
TRC-G835800-1G 1g $191 Buy
TRC-G835800-10G 10g $1438 Buy
FG23710 100g $254 Buy
FG23710 250g $390 Buy
FG23710 500g $600 Buy

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Chemical Properties, Uses, Production

Chemical Properties

Beige crystals, melting point 215-216°C (189-191.5°C).

Uses

Famotidine intermediate.

Definition

Famotidine EP Impurity H is chemically (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride. It is also known as Famotidine Isothiourea Impurity . Famotidine EP Impurity H can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Famotidine.

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Preparation Products And Raw materials

Global Suppliers ( 179)
Supplier Tel Email Country ProdList Advantage
Shandong WorldSun Biological Technology Co., Ltd. 0531-88723173 18596073690 1047208234@qq.com China 8177 58
Scinova Biotech(Guangzhou) Co., Ltd. 13268215580 scinova_sales@163.com China 7011 58
Wuhan haorong Biotechnology Co., Ltd 13217229939 773651767@qq.com China 4497 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 18915873328 18915873328 sales@xianglongpharm.com China 11049 58
Wudi Rongchuan Pharmaceutical and Chemical Technology Co., Ltd. 021-5147-3705 17852115892 wxj@yananpharm.com China 64 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56

View Latest Price from (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Famotidine EP Impurity H pictures 2025-12-19 Famotidine EP Impurity H
88046-01-9
10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride pictures 2021-12-22 (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride
88046-01-9
$100.00 1KG 98% 500ton/Month Qiuxian Baitai New Material Co., LTD
(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride pictures 2021-11-24 (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride
88046-01-9
$10.00 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
Famotidine EP Impurity H DiHCl Famotidine Impurity H DiHCl N-[4-[[(amino iminomethyl) thio]-methyl]-2-thiazolyl]-guanidine dihydrochloride (FMT-II) Carbamimidothioic acid [2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl ester dihydrochloride N-(4-(((AMINOIMINOMETHYL)THIO)METHYL)-2-THIAZOLYL)GUANIDINE S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea 2HCl S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea dihydrochloride N-[4-(Aminoiminomethyl)Thiomethyl-2-Thiazolyl]Guanidine Dihydrochloride N"-[4-(Aminoiminomethyl)thiomethyl-2-thiazolyl]guanidine2HCl Carbamimidothioic acid(2-aminoiminomethyl)amino)-4-Thiazolyl)methyl ester (2-((diaminomethylene)amino)thiazol-4-yl)methyl carbamimidothioate diHCl Carbamimidothioic Acid [2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl Ester DiHCl S-(2-Guanidino-4-thiazolyl)methylisothiour Famotidine EP Impurity H Dihydrochloride Famotidine Impurity 13 Famotidine Isothiourea Impurity [2-[(Diaminomethylidene)amino]thiaz Famotidine Related Compound h (2-guanidinothiazol-4-yl)methyl carbamimidothioate dihydrochloride amino(methylsulfanyl)methaniminium chloride (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochlor... Famotidine Impurity H as Dihydrochloride Famotidine EP Impurity H as Dihydrochloride (2-Guanidinothiazol-4-yl)methyl carbamimidothioate dihydrochloride (Famotidine Impurity) Famotidine Impurity 13 (Famotidine EP Impurity H Dihydrochloride) Iso Thiourea Hcl. (ITU) ISO THIOUREA [(S)-((2-GUANIDINO-4-THIAZOLYL) METHYLISOTHIOUREA DIHYDROCHLORIDE](ITU) ((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride S-[(2-Guanidino-4-thiazolyl)] isothiourea dihydrochloride Famotidine EP Impurity H HCL (2-carbamimidamido-1,3-thiazol-4-yl)methyl carbamimidothioate dihydrochloride 2-[(Diaminomethylidene)amino]thiazol-4-yl]methyl Carbamimidothioate Dihydrochloride (S)-((2-Guanidino-4-thiazolyl)methylisothiourea (2-guanidinothiazol-4-yl)methyl carbamimidothioate DiHCl (2-((diaminomethylene)amino)thiazol-4-yl)methyl carbamimidothioate dihydrochloride Famotidine double salt intermediate Carbamimidothioic acid, [2-[(aminoiminomethyl)amino] -4-thiazolyl]methyl ester, dihydrochloride (Famotidine Impurity) 88046-01-9 C6H12Cl2N6S2 C6H10N6S22HCl Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds