ChemicalBook >> CAS DataBase List >>2,5-Dimethoxytetrahydrofuran

2,5-Dimethoxytetrahydrofuran

CAS No.
696-59-3
Chemical Name:
2,5-Dimethoxytetrahydrofuran
Synonyms
DMTHF;DIMETHOXYTETRAHYDROFURAN;TETRAHYDRO-2,5-DIMETHOXYFURAN;5-DiMethoxytetrahydrofuran;cis,trans-2,5-Dimethoxytetrahydrofuran;Protectol DMT;Dimethoxytetrahydr;2,5-Dimethoxytetrahy;Atropine Impurity 15;2,5-DIMETHOXYTETRAHYDROFURAN
CBNumber:
CB6728092
Molecular Formula:
C6H12O3
Molecular Weight:
132.16
MDL Number:
MFCD00005359
MOL File:
696-59-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:28:04

2,5-Dimethoxytetrahydrofuran Properties

Melting point -45 °C
Boiling point 145-147 °C(lit.)
Density 1.023 g/mL at 20 °C(lit.)
vapor pressure 5 hPa (20 °C)
refractive index n20/D 1.418
Flash point 95 °F
storage temp. Store below +30°C.
solubility 300g/l
form Liquid
color Clear colorless to slightly yellow
PH 5 (300g/l, H2O, 20℃)
explosive limit 2.0-12.3%(V)
Water Solubility 350 g/L (20 ºC)
Sensitive Air & Light Sensitive
BRN 104261
InChI 1S/C6H12O3/c1-7-5-3-4-6(8-2)9-5/h5-6H,3-4H2,1-2H3
InChIKey GFISDBXSWQMOND-UHFFFAOYSA-N
SMILES COC1CCC(OC)O1
LogP 0.34 at 20℃
CAS DataBase Reference 696-59-3(CAS DataBase Reference)
NIST Chemistry Reference Furan, tetrahydro-2,5-dimethoxy-(696-59-3)
EPA Substance Registry System Furan, tetrahydro-2,5-dimethoxy- (696-59-3)
UNSPSC Code 12352112
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Skull and Crossbones (GHS06)
GHS02,GHS06
Signal word  Danger
Hazard statements  H226-H315-H331
Precautionary statements  P210-P233-P240-P241-P303+P361+P353-P304+P340+P311
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,Xn
Risk Statements  10-36/37/38-36-20/21
Safety Statements  26-36-36/37/39-16
RIDADR  UN 1993 3/PG 3
WGK Germany  1
Autoignition Temperature >205 °C
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29321900
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 3 Inhalation
Flam. Liq. 3
Skin Irrit. 2
Toxicity LD50 orally in Rabbit: 2040 mg/kg
REACH Registrations Active
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
3
2

2,5-Dimethoxytetrahydrofuran price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D137103 2,5-Dimethoxytetrahydrofuran, mixture of cis and trans 98% 696-59-3 100g $73.3 2026-04-30 Buy
Sigma-Aldrich 8.02961 2,5-Dimethoxytetrahydrofuran (mixture of cis- and trans isomers) for synthesis 696-59-3 25mL $39.3 2026-04-30 Buy
Sigma-Aldrich D137103 2,5-Dimethoxytetrahydrofuran, mixture of cis and trans 98% 696-59-3 500g $139 2026-04-30 Buy
Sigma-Aldrich 8.02961 2,5-Dimethoxytetrahydrofuran (mixture of cis- and trans isomers) for synthesis 696-59-3 50mL $47.3 2026-04-30 Buy
Sigma-Aldrich 8.02961 2,5-Dimethoxytetrahydrofuran (mixture of cis- and trans isomers) for synthesis 696-59-3 250ML $206 2026-04-30 Buy
Product number Packaging Price Buy
D137103 100g $73.3 Buy
8.02961 25mL $39.3 Buy
D137103 500g $139 Buy
8.02961 50mL $47.3 Buy
8.02961 250ML $206 Buy

2,5-Dimethoxytetrahydrofuran Chemical Properties, Uses, Production

Chemical Properties

Colorless to light yellow liqui

Uses

2,5-Dimethoxytetrahydrofuran is a tetrahydrofuran derivative that finds application in proteomics research and in organic synthesis. It is also used as an intermediate for atropine sulfate, which is an anticholinergic drug. Further, it acts as a precursor of butanediol. In addition to this, it is used as a photographic hardener and as disinfectant in formulations.

Synthesis

2,5-Dimethoxytetrahydrofuran is prepared by catalytic hydrogenation of 2,5-dialkoxy-2,5-dihydrofurans.

Solubility in water

Practically insoluble in H2O; soluble in MeOH, Et2O, THF.

Precautions

Flammable liquids must be stored in a cool, ventilated place. Noxious by inhalation, ingestion, or by contact with skin. Use in a fume hood.

67-56-1
79668-89-6
696-59-3
Synthesis of 2,5-Dimethoxytetrahydrofuran from Methanol and 3,8-Dioxa-2,9-disiladeca-4,6-diene, 2,2,9,9-tetramethyl-
Global Suppliers ( 484)
Supplier Tel Email Country ProdList Advantage
Anhui Royal Chemical Co., Ltd. +86-02586655873 +86-13962173137 marketing@royal-chem.com China 137 60
ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD 0571-87322520 19265846165 sales@zetchem.com China 466 55
Shandong Qianyuan Polymer Material Co. , Ltd. 18678041314 18765609661 2547772582@qq.com China 989 58
Hubei ZhongKe XinChen Technology Ltd. 欢迎详询+微信 18827688560 starvips@qq.com China 497 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Beijing Mediking Biopharm Co., Ltd 010-81769521,89753524,81760121 15901403431 sales01@mediking.cn China 100 68

View Latest Price from 2,5-Dimethoxytetrahydrofuran manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,5-Dimethoxytetrahydrofuran pictures 2026-10-12 2,5-Dimethoxytetrahydrofuran
696-59-3
0.99 RongNa Biotechnology Co.,Ltd
2,5-Dimethoxytetrahydrofuran pictures 2026-10-09 2,5-Dimethoxytetrahydrofuran
696-59-3
1kg 99%min 20tons HANGZHOU HAILAN CHEMICAL CO.,LTD.
2,5-Dimethoxytetrahydrofuran pictures 2026-10-09 2,5-Dimethoxytetrahydrofuran
696-59-3
1KG 98%min 20 Tons WUHAN FORTUNA CHEMICAL CO., LTD
2,5-Dimethoxytetrahydrofuran,c&t tetrahydro-2,5-dimethoxy-fura FURAN, TETRAHYDRO-2,5-DIMETHOXY 2,5-DIMETHOXYTETRAHYDROFURAN 2,5-Dimethoxytetrahydrofuran, mixture of cis and trans 2,5-DIMETHOXY-TETRAHYDROFURAN (CIS+TRANS ) 2,5-DIMETHOXYTETRAHYDROFURAN, 98%, MIXTU RE OF ISOMERS 2,5-Dimethoxy Tetrahydrofulan 2,5-Dimethoxytetrahydrofuran (cis- and trans- mixture) 2,5-Dimethoxytetrahydrofuran, 99%, mixtureof cis- and trans isomers 2,3,4,5-Tetrahydro-2,5-dimethoxyfuran TETRAHYDRO-2,5-DIMETHOXYFURAN Dimethoxytetrahydr Тетрагидро-2,5-диметоксифуран, 2,5-diMeTHF Тетрагидро-2,5-диметоксифуран, 2,5-diMeTHF, 2,5-Dimethoxytetrahydrofuran 2,5-dimethoxytetrahydrofuran,mixtureofcis-andtransisomers dimethoxytetrahydrofuran(tetrahydro-2,5-demethoxy-furan) Protectol DMT 2,5-Dimethoxytetrahydrofuran,mixture of cis and trans isomers ,99% 2,5-Dimethoxytetrahy 2,5-DiMethoxytetrahydrofuran, Mixture of cis- and trans isoMers, 99% 100GR 2,5-DiMethoxytetrahydrofuran, Mixture of cis- and trans isoMers, 99% 500GR 5-DiMethoxytetrahydrofuran 2,5-DIMETHOXYTETRAHYDROFURAN (MIXTURE OF DiMethoxytetrahydrofuran, Mixture of cis and 2,5-DiMethoxytetrahydrofuran, 98%, Mixture of cis and trans 2,5- twoMethoxytetrahydrofuran 2,5-Dimethoxytetrahydrofuran, mixture of cis and trans 98% Atropine Impurity 15 2,5-Dimethoxytetrahydrofuran (cis- and trans- mixture)> 2,5-Dimethoxytetrahydrofuran (cis and trans isomers) 2,5-Dimethoxytetrahydrofuran, mixture of cis- and trans isom... 2,5-Dimethoxytetrahydrofuran CAS 696-59-3 with factory price and marketable products 2,5--Dimethoxytetrahydrfuran Ilaprazole Impurity 21 (cis- and trans- mixture) 2,5-Dimethoxytetrahydrofuran, mixture of cis and trans 2,3-Difluorobenzo[1,4]dioxane 2,5-dimethoxytetrahydrofuran (Mixture of cis & trans isomer) cis,trans-2,5-Dimethoxytetrahydrofuran DIMETHOXYTETRAHYDROFURAN DMTHF 696-59-3 693-59-3 4334-85-8 Heterocyclic Building Blocks Furans Building Blocks Building Blocks C4 to C7 Chemical Synthesis Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Pharmaceutical Oxygen cyclic compounds Aromatic Hydrocarbons (substituted) & Derivatives Furan&Benzofuran Furans