3-PHENYLAMINO-PROPIONIC ACID
- CAS No.
- 5652-38-0
- Chemical Name:
- 3-PHENYLAMINO-PROPIONIC ACID
- Synonyms
- NSC 54626;3-(Phenylamino);N-Phenyl-b-alanine;RARECHEM AL BO 0162;β-Alanine, N-phenyl-;N-PHENYL-BETA-ALANINE;3-Anilinopropionic acid;3-Anilinopropanoic acid;3-Phenylammoniopropanoate;N-(2-Carboxyethyl)aniline
- CBNumber:
- CB6740092
- Molecular Formula:
- C9H11NO2
- Molecular Weight:
- 165.19
- MDL Number:
- MFCD00089905
- MOL File:
- 5652-38-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2922498590 |
3-PHENYLAMINO-PROPIONIC ACID price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P319638 | 3-(Phenylamino)propanoicAcid | 5652-38-0 | 100mg | $40 | 2021-12-16 | Buy |
| TRC | P319638 | 3-(Phenylamino)propanoicAcid | 5652-38-0 | 1g | $140 | 2021-12-16 | Buy |
| ChemScene | CS-W021779 | 3-(Phenylamino)propanoicacid 97.16% | 5652-38-0 | 10g | $205 | 2021-12-16 | Buy |
| Matrix Scientific | 126965 | 3-(Phenylamino)propanoicacid >95% | 5652-38-0 | 10g | $450 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0102068 | 3-PHENYLAMINO-PROPIONIC ACID 95.00% | 5652-38-0 | 1G | $765.23 | 2021-12-16 | Buy |
3-PHENYLAMINO-PROPIONIC ACID Chemical Properties,Uses,Production
Uses
3-(Phenylamino)propanoic Acid is used in the preparation of spiroheterocycles as filamin A (FLNA) binding antiinflammatory analgesics.
Synthesis
57-57-8
62-53-3
5652-38-0
The general procedure for the synthesis of 3-anilinopropionic acid from β-propiolactone and aniline was as follows: aniline (5.00 g) was dissolved in acetonitrile (30 ml) and heated to reflux. Subsequently, β-propiolactone (3.36 ml) was added slowly and dropwise. The reflux condition was maintained and the reaction was continued for 3 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in aqueous sodium hydroxide solution and the aqueous phase was washed with ether. The pH of the aqueous phase was adjusted to 4-5 with hydrochloric acid and subsequently extracted with ether. The organic layers were combined, washed sequentially with water and saturated saline, and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure. Finally, the residue was purified by silica gel column chromatography (eluent ratio of chloroform:methanol=9:1) to afford the target product 3-anilinopropionic acid (2.08 g, 23% yield).
References
[1] Patent: EP1452526, 2004, A1. Location in patent: Page 105
[2] Journal of the American Chemical Society, 1951, vol. 73, p. 3168,3171
[3] Patent: US2008/153871, 2008, A1. Location in patent: Page/Page column 24
3-PHENYLAMINO-PROPIONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3969 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | sales@hengbeichem.cn | China | 6854 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42952 | 64 |
View Lastest Price from 3-PHENYLAMINO-PROPIONIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 3-PHENYLAMINO-PROPIONIC ACID
5652-38-0
|
US $2.00 / KG | 1g | 98%min | ask | Career Henan Chemical Co |
-
- 3-PHENYLAMINO-PROPIONIC ACID
5652-38-0
- US $2.00 / KG
- 98%min
- Career Henan Chemical Co
5652-38-0(3-PHENYLAMINO-PROPIONIC ACID)Related Search:
1of4
