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Crotonic anhydride

CAS No.
623-68-7
Chemical Name:
Crotonic anhydride
Synonyms
Nsc97397;Wln: 2U1vov1U2;CROTONIC ANHYDRIDE;2-Butensureanhydrid;CROTONSAEUREANHYDRID;2-butenoic anhydride;Dicrotonic anhydride;Biscrotonic anhydride;crotonicacidanhydride;But-2-enoic anhydride
CBNumber:
CB6751209
Molecular Formula:
C8H10O3
Molecular Weight:
154.17
MDL Number:
MFCD00009286
MOL File:
623-68-7.mol
MSDS File:
SDS
Last updated:2026-05-28 03:49:25
Product description Number Pack Size Price
Crotonic anhydride (mixture of cis and trans isomers) for synthesis 8.22002 100mL $43.4
Crotonic Anhydride >98.0%(T) C0420 25g $17
Crotonic anhydride TRC-C818793-500MG 500mg $72
Crotonic anhydride TRC-C818793-2.5G 2.5g $97
Crotonic anhydride TRC-C818793-1G 1g $84
More product size

Crotonic anhydride Properties

Melting point -20°C
Boiling point 248 °C(lit.)
Density 1.04 g/mL at 25 °C(lit.)
vapor pressure 1 hPa (25 °C)
refractive index n20/D 1.473(lit.)
Flash point 231 °F
storage temp. Store below +30°C.
solubility soluble in Ether
form clear liquid
color Colorless to Light orange to Yellow
InChI 1S/C8H10O3/c1-3-5-7(9)11-8(10)6-4-2/h3-6H,1-2H3/b5-3+,6-4+
InChIKey VJDDQSBNUHLBTD-GGWOSOGESA-N
SMILES O(C(=O)\C=C\C)C(=O)\C=C\C
CAS DataBase Reference 623-68-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII N521PMQ949
EPA Substance Registry System 2-Butenoic acid, anhydride (623-68-7)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Environment (GHS09)
GHS05,GHS09
Signal word  Danger
Hazard statements  H314-H400
Precautionary statements  P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 3
WGK Germany  3
RTECS  GQ6125000
Autoignition Temperature 290 °C
TSCA  TSCA listed
HS Code  2916 19 95
HazardClass  8
PackingGroup  III
Storage Class 8A - Combustible, corrosive hazardous materials
Hazard Classifications Aquatic Acute 1
Eye Dam. 1
Skin Corr. 1B
Hazardous Substances Data 623-68-7(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 2061 mg/kg
REACH Registrations Active
NFPA 704
0
3 0

Crotonic anhydride price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.22002 Crotonic anhydride (mixture of cis and trans isomers) for synthesis 623-68-7 100mL $43.4 2026-04-30 Buy
TCI Chemical C0420 Crotonic Anhydride >98.0%(T) 623-68-7 25g $17 2026-04-30 Buy
TRC TRC-C818793-500MG Crotonic anhydride 623-68-7 500mg $72 2026-06-03 Buy
TRC TRC-C818793-2.5G Crotonic anhydride 623-68-7 2.5g $97 2026-06-03 Buy
TRC TRC-C818793-1G Crotonic anhydride 623-68-7 1g $84 2026-06-03 Buy
Product number Packaging Price Buy
8.22002 100mL $43.4 Buy
C0420 25g $17 Buy
TRC-C818793-500MG 500mg $72 Buy
TRC-C818793-2.5G 2.5g $97 Buy
TRC-C818793-1G 1g $84 Buy

Crotonic anhydride Chemical Properties,Uses,Production

Uses

Crotonic anhydride belongs to the organic chemical intermediates, is an important organic chemical raw materials, in the dyestuff industry is used as fur dyes, reactive dyestuffs intermediates; in the cosmetic industry is used as a high-grade cosmetics, such as skin creams, hair conditioners, shampoos, creams, and other additives; in the pharmaceutical industry as a pharmaceutical antimicrobial drugs, sulfonamides as raw materials for drugs. Crotonic anhydride can also be used in the preparation of butenoic acid fiber and coal dye, hair dye, color developer, epoxy resin curing agent, petroleum additives, rubber antioxidants and other synthetic.

Chemical Properties

Colorless to pale yellow liquid

Uses

Crotonic anhydride is also known as 2-butenoic anhydride is commonly used as a precursor in the synthesis of polymers. Its reactive anhydride group makes it an effective acylating agent in esterification reactions, facilitating the formation of esters by reacting with alcohols.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 593, 1992 DOI: 10.1016/S0040-4039(00)92318-9

Safety Profile

Moderately toxic by ingestion. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Crotonic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 142)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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SIMAGCHEM CORP
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ShanDong Look Chemical Co.,Ltd.
17653113209 13065062079 sales01@sdlookchemical.com China 2921 58
Shandong Zhishang New Material Co., Ltd.
+8617653113209 sales002@sdzschem.com China 2921 58

View Lastest Price from Crotonic anhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Crotonic anhydride pictures 2025-04-04 Crotonic anhydride
623-68-7
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
	Crotonic anhydride pictures 2019-07-06 Crotonic anhydride
623-68-7
$7.00 1kg 99% 100kg Career Henan Chemical Co
2-Butenoicacid,anhydride anhydridkyselinykrotonove crotonicacidanhydride CROTONIC ANHYDRIDE 2-butenoic anhydride TRANS-2-BUTENOIC ANHYDRIDE 2-Butensureanhydrid CROTONSAEUREANHYDRID trans-crotonic acid anhydride Bis[(E)-2-butenoic acid]anhydride Biscrotonic anhydride Dicrotonic anhydride Bis(2-butenoic)anhydride Di(2-butenoic)anhydride Nsc97397 Wln: 2U1vov1U2 But-2-enoic anhydride Crotonic anhydride, 2-Butenoic anhydride (E)-but-2-enoic anhydride 2-Butenoic acid,1,1'-anhydride (E)-2-butenoic acid [(E)-1-oxobut-2-enyl] ester (2E)-2-Butenoic anhydride Crotonic Anhydride > CROTONIC ANHYDRIDE (MIXTURE OF CIS AND T Crotonic anhydride ISO 9001:2015 REACH 623-68-7 CH3CHCHCO2O Pharmaceutical Intermediates