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Crotonic anhydride

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Crotonic anhydride manufacturers

  • Crotonic anhydride
  • 	Crotonic anhydride pictures
  • $7.00
  • 2019-07-06
  • CAS: 623-68-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
Crotonic anhydride Basic information
Uses
Product Name:Crotonic anhydride
Synonyms:2-Butenoicacid,anhydride;anhydridkyselinykrotonove;crotonicacidanhydride;CROTONIC ANHYDRIDE;2-butenoic anhydride;TRANS-2-BUTENOIC ANHYDRIDE;2-Butensureanhydrid;CROTONSAEUREANHYDRID
CAS:623-68-7
MF:C8H10O3
MW:154.17
EINECS:210-807-1
Product Categories:Pharmaceutical Intermediates
Mol File:623-68-7.mol
Crotonic anhydride Structure
Crotonic anhydride Chemical Properties
Melting point -20°C
Boiling point 248 °C(lit.)
density 1.04 g/mL at 25 °C(lit.)
vapor pressure 1 hPa (25 °C)
refractive index n20/D 1.473(lit.)
Fp 231 °F
storage temp. Store below +30°C.
solubility soluble in Ether
form clear liquid
color Colorless to Light orange to Yellow
InChI1S/C8H10O3/c1-3-5-7(9)11-8(10)6-4-2/h3-6H,1-2H3/b5-3+,6-4+
InChIKeyVJDDQSBNUHLBTD-GGWOSOGESA-N
SMILESO(C(=O)\C=C\C)C(=O)\C=C\C
CAS DataBase Reference623-68-7(CAS DataBase Reference)
EPA Substance Registry System2-Butenoic acid, anhydride (623-68-7)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45
RIDADR UN 3265 8/PG 3
WGK Germany 3
RTECS GQ6125000
Autoignition Temperature290 °C
TSCA TSCA listed
HS Code 2916 19 95
HazardClass 8
PackingGroup III
Storage Class8A - Combustible, corrosive hazardous materials
Hazard ClassificationsAquatic Acute 1
Eye Dam. 1
Skin Corr. 1B
Hazardous Substances Data623-68-7(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 2061 mg/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
Crotonic anhydride Usage And Synthesis
UsesCrotonic anhydride belongs to the organic chemical intermediates, is an important organic chemical raw materials, in the dyestuff industry is used as fur dyes, reactive dyestuffs intermediates; in the cosmetic industry is used as a high-grade cosmetics, such as skin creams, hair conditioners, shampoos, creams, and other additives; in the pharmaceutical industry as a pharmaceutical antimicrobial drugs, sulfonamides as raw materials for drugs. Crotonic anhydride can also be used in the preparation of butenoic acid fiber and coal dye, hair dye, color developer, epoxy resin curing agent, petroleum additives, rubber antioxidants and other synthetic.
Chemical PropertiesColorless to pale yellow liquid
UsesCrotonic anhydride is also known as 2-butenoic anhydride is commonly used as a precursor in the synthesis of polymers. Its reactive anhydride group makes it an effective acylating agent in esterification reactions, facilitating the formation of esters by reacting with alcohols.
Synthesis Reference(s)Tetrahedron Letters, 33, p. 593, 1992 DOI: 10.1016/S0040-4039(00)92318-9
Safety ProfileModerately toxic by ingestion. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Crotonic anhydride Preparation Products And Raw materials
Preparation Products(N-Crotonyl)-(2R)-bornane-10,2-sultam
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