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1,2-Bis(2-chloroethoxy)ethane

1,2-Bis(2-chloroethoxy)ethane Structure
1,2-Bis(2-chloroethoxy)ethane structure
CAS No.
112-26-5
Chemical Name:
1,2-Bis(2-chloroethoxy)ethane
Synonyms
TRIGLYCOL DICHLORIDE;TRIETHYLENE GLYCOL DICHLORIDE;1,2-Bis(2-chL;PEG2-Dichloride;oroethoxy)ethane;'TRIGLYCOL DICHLORIDE';Dichlorotriethyl ether;triglycoldichlorideether;Bis(2-chloroethoxy)ethane;1,2-BIS(CHLORETHOXY)ETHAN
CBNumber:
CB6764713
Molecular Formula:
C6H12Cl2O2
Molecular Weight:
187.06
MDL Number:
MFCD00000976
MOL File:
112-26-5.mol
MSDS File:
SDS
Last updated:2026-05-28 04:13:16
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1,2-Bis(2-chloroethoxy)ethane Properties

Melting point -31°C
Boiling point 235 °C(lit.)
Density 1.197 g/mL at 25 °C(lit.)
refractive index n20/D 1.461(lit.)
Flash point 250 °F
storage temp. Inert atmosphere,Room Temperature
solubility insoluble
form clear liquid
color Colorless to Almost colorless
Water Solubility insoluble
BRN 506177
Henry's Law Constant 1.3×101 mol/(m3Pa) at 25℃, HSDB (2015)
InChI InChI=1S/C6H12Cl2O2/c7-1-3-9-5-6-10-4-2-8/h1-6H2
InChIKey AGYUOJIYYGGHKV-UHFFFAOYSA-N
SMILES C(OCCCl)COCCCl
CAS DataBase Reference 112-26-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 28JQ82M13J
NIST Chemistry Reference Ethane, 1,2-bis(2-chloroethoxy)-(112-26-5)
EPA Substance Registry System 1,2-Bis(2-chloroethoxy)ethane (112-26-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H312-H315-H318-H335
Precautionary statements  P261-P264-P280-P301+P310-P302+P352+P312-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn
Risk Statements  19-21/22-37/38-41-36/37/38
Safety Statements  26-36/37/39
RIDADR  UN 2810 6.1/PG 3
WGK Germany  3
RTECS  KH4900000
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  29091900
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data 112-26-5(Hazardous Substances Data)
REACH Registrations Active
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
2 0

1,2-Bis(2-chloroethoxy)ethane price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 241628 1,2-Bis(2-chloroethoxy)ethane 97% 112-26-5 100g $80.2 2026-04-30 Buy
Sigma-Aldrich 241628 1,2-Bis(2-chloroethoxy)ethane 97% 112-26-5 500g $281 2026-04-30 Buy
TCI Chemical B0471 1,2-Bis(2-chloroethoxy)ethane >98.0%(GC) 112-26-5 25mL $34 2026-04-30 Buy
TCI Chemical B0471 1,2-Bis(2-chloroethoxy)ethane >98.0%(GC) 112-26-5 500mL $105 2026-04-30 Buy
TRC TRC-B405016-5G 1,2-Bis(2-chloroethoxy)ethane 112-26-5 5g $91 2026-06-03 Buy
Product number Packaging Price Buy
241628 100g $80.2 Buy
241628 500g $281 Buy
B0471 25mL $34 Buy
B0471 500mL $105 Buy
TRC-B405016-5G 5g $91 Buy

1,2-Bis(2-chloroethoxy)ethane Chemical Properties, Uses, Production

Chemical Properties

clear colorless to pale yellow liquid. Insoluble in water. Combustible.

Uses

Solvent for hydrocarbons, oils, etc.; extractant; intermediate for resins and insecticides; organic synthesis.

Uses

1,2-Bis(2-chloroethoxy)ethane is used as pharmaceutical intermediate.

Uses

1,2-bis(2-chloroethoxy)ethane was used in the synthesis of 1,1′-[1,2-ethanediylbis(oxy-1,2-ethanediyl)]bis[3-methyl-1H-imidazolium-1-yl] chloride.

Synthesis

Triethylene glycol (0.28 mol) and pyridine (49 mL, 0.61 mol) were mixed in benzene (250 mL) in a dry reaction flask and the resulting reaction mixture was heated to reflux. Dichlorosulfoxide (0.61 mole) was added to the reaction mixture slowly and dropwise for about 3 hours. At the end of the addition the reaction mixture was kept at reflux and stirred for 16 hours. At the end of the reaction the resulting reaction mixture was cooled to room temperature and hydrochloric acid (6.3 mL, 11.8 M) diluted in diluted water (50 mL) was slowly added dropwise to the above reaction mixture for about 15 minutes. The upper benzene solution in the reaction mixture was separated and concentrated under reduced pressure to evaporate the benzene solution and the resulting residue was the target product molecule 1,2-bis(2-chloroethoxy)ethane.

1,2-Bis(2-chloroethoxy)ethane synthesis

112-27-6
112-26-5
Synthesis of 1,2-Bis(2-chloroethoxy)ethane from Triethylene glycol

1,2-Bis(2-chloroethoxy)ethane Preparation Products And Raw materials

Raw materials

Triethylene glycol bis(chloroformate) 2-(2-(2-chloroethoxy)ethoxy)-ethanol-p-toluenesulfonate Diethylene glycol bis(2-chloroethyl) ether 2-Chloromethoxyethylchloride Ethylene oxide
2,2'-Dichlorodiethyl ether Tri(Ethylene Glycol) DI-P-Toluenesulfonate 2-[2-(2-Chloroethoxy)ethoxy]ethanol Ethylene 1,4-Dioxane

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Preparation Products

Pentaethylene glycol dichloride [2,5]-Dibenzo-21-crown-7 2-[2-(2-Azidoethoxy)ethoxy]ethanamine 3,6-Dioxa-1,8-octanedithiol

1,2-Bis(2-chloroethoxy)ethane Suppliers

Global Suppliers ( 270)
Supplier Tel Email Country ProdList Advantage
Yangzhou Prince Chemical Co., Ltd 0514-84248359 13328140016;15052570758;15949050037 sales@princechem.com China 99 58
Sanmenxia Aoke Chemical Industry Co., Ltd. 13523980263; 13523980263 1838829861@qq.com China 44 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Supplier Advantage
Yangzhou Prince Chemical Co., Ltd 58
Sanmenxia Aoke Chemical Industry Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60

View Latest Price from 1,2-Bis(2-chloroethoxy)ethane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,2-Bis(2-chloroethoxy)ethane pictures 2025-06-27 1,2-Bis(2-chloroethoxy)ethane
112-26-5
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
1,2-Bis(2-chloroethoxy)ethane pictures 2025-06-20 1,2-Bis(2-chloroethoxy)ethane
112-26-5
 $9.00-35.00 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
1,2-Bis(2-chloroethoxy)ethane pictures 2022-01-04 1,2-Bis(2-chloroethoxy)ethane
112-26-5
 1g 99%minGC 10Tons/month Shanghai Rlavie Technology Co ltd

1,2-Bis(2-chloroethoxy)ethane Spectrum

1,2-Bis(2-chloroethoxy)ethane(112-26-5)MS1,2-Bis(2-chloroethoxy)ethane(112-26-5)1HNMR1,2-Bis(2-chloroethoxy)ethane(112-26-5)13CNMR1,2-Bis(2-chloroethoxy)ethane(112-26-5)IR11,2-Bis(2-chloroethoxy)ethane(112-26-5)IR21,2-Bis(2-chloroethoxy)ethane(112-26-5)Raman

112-26-5 (1,2-Bis(2-chloroethoxy)ethane) Related Search:

Triethylene glycol Diethylene glycol Dipropylene glycol Hexafluoroethane Triethylene glycol bis(2-ethylhexanoate)
2,2'-Dichlorodiethyl ether 2-Butoxyethanol 2-Methyl-2,4-pentanediol Dichloroethane Sodium dichloroisocyanurate
1,4-Butanediol Thionyl chloride Diethyl ether Ethane Chloroethane
Diethoxymethane Triethylene glycol monomethyl ether Pentachloroethane

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Ethane, 1,2-bis(2-chloroethoxy)- 1,2-bis(2-chloroethoxy)-ethan 1,2-Bis(chloroethoxy)ethane 1,8-Dichloro-3,6-dioxaoctane 1-Chloro-2-[2-(2-chloroethoxy)ethoxy]ethane 2-(2-Chlorethoxy)ethyl 2'-chlorethyl ether 2-(2-chlorethoxy)ethyl2’-chlorethylether Bis(2-chloroethoxy)ethane triglycoldichlorideether 1,2-Bis(2-chL oroethoxy)ethane 1,2-BIS(2-CHLOROETHOXY)ETHANE (SEE 2229) Triglycol dichloride, Dichlorotriethylene dioxide, Tri(ethylene glycol) dichloride 1,2-BIS(CHLORETHOXY)ETHAN 1,2-BIS(2-CHLOROETHOXY)ETHANE 2-(2-CHLOROETHOXY)ETHYL 2'-CHLOROETHYL ETHER DICHLOROTRIETHYLENE DIOXIDE DI(2-CHLOROETHYL) CELLOSOLVE ETHYLENE GLYCOL BIS(2-CHLOROETHYL) ETHER Di(2-chloroethyl) Cellosolve Ethylene Glycol Bis(2-chloroethyl) Ether Triglycol dichlorideDichlorotriethylene dioxide 1,2-Bis(2-chloroethoxy)ethane,97% 1,2-Bis(2-chloroethoxy)ethane,98% 1,2-Bis(2-chloroethoxy)ethane,99+% 1,2-Bis(2-chloroethoxy)ethane, 97% 100ML 1,2-BIS-(2-CHLOROETHOXY) ETHANE FOR SYNT TRIGLYCOL DICHLORIDE 'TRIGLYCOL DICHLORIDE' TRIETHYLENE GLYCOL DICHLORIDE 1,2-Bis(2-chloroethoxy)ethane > 112-26-5 C6H12Cl2O2 1,2-Bis(2-chloroethoxy)ethane PEG2-Dichloride Dichlorotriethyl ether 112-26-5 C6H12Cl2O2 ClCH2CH2OCH2CH2OCH2CH2Cl Building Blocks Oxygen Compounds Organic Building Blocks Ethers Building Blocks C2 to C7 Chemical Synthesis Ethers Organic Building Blocks Oxygen Compounds