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2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL structure

CAS No.: 5197-62-6

Chemical Name:: 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL

Synonyms: 8-Chloro-3,6-dioxaoctane-1-ol;2-[2-(2-Chloroethoxy)ethoxy]ethanol,95%;CEEE;NSC 2636;8-Chloro-3,6-dioxaoctanol;Chloroethoxyethoxy]ethanol;8-Chloro-3,6-dioxa-1-octanol;2-Chloroethoxy Ethoxy Ethanol;2-(2-CHLOROETHOXY)ETHOXYETHANOL;Triethylene glycol monochloride

CBNumber:: CB0333360

Molecular Formula:: C6H13ClO3

Molecular Weight:: 168.62

MDL Number:: MFCD00002874

MOL File:: 5197-62-6.mol

MSDS File:: SDS

Last updated:2026-01-13 11:13:56

Product description	Number	Pack Size	Price
2-[2-(2-Chloroethoxy)ethoxy]ethanol 96%	162973	10g	$49.42
2-[2-(2-Chloroethoxy)ethoxy]ethanol >96.0%(GC)	C1416	25g	$52
2-[2-(2-Chloroethoxy)ethoxy]ethanol >96.0%(GC)	C1416	100g	$131
2-[2-(2-Chloroethoxy)ethoxy]ethanol >96.0%(GC)	C1416	500g	$393
2-[2-(2-Chloroethoxy)ethoxy]ethanol	C365760	50g	$475
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2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Properties

Boiling point	117-120 °C5 mm Hg(lit.)
Density	1.16 g/mL at 25 °C(lit.)
refractive index	n20/D 1.458(lit.)
Flash point	225 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly)
pka	14.36±0.10(Predicted)
form	Liquid
color	Clear slightly yellow
BRN	1739194
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
InChI	InChI=1S/C6H13ClO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-6H2
InChIKey	KECMLGZOQMJIBM-UHFFFAOYSA-N
SMILES	C(O)COCCOCCCl
CAS DataBase Reference	5197-62-6(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39

WGK Germany

HS Code

29094990

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
0		0

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	162973	2-[2-(2-Chloroethoxy)ethoxy]ethanol 96%	5197-62-6	10g	$49.42	2025-07-31	Buy
TCI Chemical	C1416	2-[2-(2-Chloroethoxy)ethoxy]ethanol >96.0%(GC)	5197-62-6	25g	$52	2025-07-31	Buy
TCI Chemical	C1416	2-[2-(2-Chloroethoxy)ethoxy]ethanol >96.0%(GC)	5197-62-6	100g	$131	2025-07-31	Buy
TCI Chemical	C1416	2-[2-(2-Chloroethoxy)ethoxy]ethanol >96.0%(GC)	5197-62-6	500g	$393	2025-07-31	Buy
TRC	C365760	2-[2-(2-Chloroethoxy)ethoxy]ethanol	5197-62-6	50g	$475	2021-12-16	Buy

Product number	Packaging	Price	Buy
162973	10g	$49.42	Buy
C1416	25g	$52	Buy
C1416	100g	$131	Buy
C1416	500g	$393	Buy
C365760	50g	$475	Buy

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Uses

2-[2-(2-Chloroethoxy)ethoxy]ethanol is used in the preparation of ethylene glycol based amino acids. 2-[2-(2-Chloroethoxy)ethoxy]ethanol is also used in the preparation of polymers for direct and amplified DNA detection.

Uses

2-[2-(2-Chloroethoxy)ethoxy]ethanol was used in the synthesis of 1-[3-(2-aminoethyl)-1H-indol-5-yloxy]-3,6-dioxa-8-mercaptooctane. It was also used in the synthesis of modified oligonucleotides bearing a disulfide or a thiol function at the 3′-end and other modifications at the 5′-end.

Synthesis

75-21-8

628-89-7

5197-62-6

The reaction material in the three-necked flask was cooled to 45-50°C and 0.7 g of boron trifluoride diethyl ether compound was added as catalyst. Subsequently, 46.2 g (1.05 mol) of ethylene oxide was slowly added under stirring conditions, and the addition rate was controlled to maintain the reaction temperature at 45-55°C, using a temperature-controlled water bath for temperature adjustment if necessary. After the addition, the reaction was continued with stirring for 0.5 h to ensure complete reaction. Upon completion of the reaction, the reaction was heated and distilled under reduced pressure to collect the middle fraction at 115-123°C (vacuum 10 mmHg) to obtain a colorless transparent liquid. Further vacuum distillation was carried out under reduced pressure to collect the middle fraction at 118-121 °C (vacuum 10 mmHg) to give 123.6 g of colorless transparent liquid with 97.7% purity in the gas phase and 73.3% overall yield.

References

[1] Patent: CN104003850, 2016, B. Location in patent: Paragraph 0039; 0040

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL synthesis

Synthesis of 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL from Triethylene glycol

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Preparation Products And Raw materials

Raw materials

2-Chloroethanol 2-(2-Chloroethoxy)ethanol Triethylene glycol ETHYLENE OXIDE Ethylene glycol

Preparation Products

2-[2-[2-(2-chloroethoxy)ethoxy]ethoxy]ethanol 1,4-Dioxane 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL t-Boc-N-Amido-PEG3-propargyl Acetic acid, [2-[2-(2-aminoethoxy)ethoxy]ethoxy]-

1,4,7,10,13-PENTAOXA-16-AZACYCLOOCTADECANE 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL 1,2-Bis(2-chloroethoxy)ethane

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2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Suppliers

Global( 210)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8629	58
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1001	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29833	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8830	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58

Supplier	Advantage
Shanghai UCHEM Inc.	58
Shanghai Time Chemicals CO., Ltd.	55
Shanxi Naipu Import and Export Co.,Ltd	58
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
Richest Group Ltd	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58

View Lastest Price from 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-02-25	2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL 5197-62-6	US $10.00 / KG	1KG	99%	5000kg/month	Shanxi Naipu Import and Export Co.,Ltd
2021-08-12	2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL 5197-62-6	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL 5197-62-6	US $1.00 / KG	1KG	98%	100KG	Career Henan Chemical Co

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
5197-62-6
US $10.00 / KG
99%
Shanxi Naipu Import and Export Co.,Ltd

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
5197-62-6
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
5197-62-6
US $1.00 / KG
98%
Career Henan Chemical Co

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Spectrum

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL(5197-62-6)MS 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL(5197-62-6)¹HNMR 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL(5197-62-6)¹³CNMR 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL(5197-62-6)IR1 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL(5197-62-6)Raman

5197-62-6(2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL)Related Search:

BETA-CHLORALOSE α-Chloralose 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL DIETHYLENE GLYCOL BIS(2-CHLOROETHYL) ETHER 1-(2-CHLORO-ETHOXY)-2-(2-METHOXY-ETHOXY)-ETHANE

1,2,3-TRI-O-BENZOYL-A-L-FUCOPYRANOSE, TRICHLOROACETIMIDATE [2-(2-METHOXY-ETHOXY)-ETHOXY]-ACETYL CHLORIDE 2-(2-hydroxyethoxy)ethyl chloroacetate 3,4,6-TRI-O-ACETYL-2-O-(2',3',4'-TRI-O-BENZOYL-A-L-FUCOPYRANOSYL)-GALACTOPYRANOSYL TRICHLOROACETIMIDATE 1-[2-HYDROXY-7-(TRICHLOROMETHYL)-4,6,8-TRIOXABICYCLO[3.3.0]OCT-3-YL]ETHANE-1,2-DIOL

5-CHLOROACETOXY-2-BENZYLOXYISOSORBIDE amicloral AURORA KA-6932 LABOTEST-BB LT00455823 METHYL (2-O-BETA-D-GLUCOPYRANOSYL)-4,6-DICHLORO-ALPHA-D-GALACTOPYRANOSIDE

AURORA KA-6933 6-CHLORO-2,2-DIMETHYLPERHYDRO[1,3]DIOXOLO[4',5':4,5]FURO[3,2-B]PYRAN-5-ONE LABOTEST-BB LT00112361

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8-Chloro-3,6-dioxaoctane-1-ol Diethylene glycol mono(2-chloroethyl) ether 2-[2-(2-Chloroethoxy)ethoxy]ethanol,95% 8-Chloro-3,6-dioxa-1-octanol 8-Chloro-3,6-dioxaoctanol NSC 2636 2-[2-(2-Chloroethoxy)ethoxy]ethanol 96% 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL 2-(2-CHLOROETHOXY)ETHOXYETHANOL TRIETHYLENE GLYCOL MONOCHLOROHYDRIN Triethylene glycol monochloride 2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL, 96+% Chloroethoxyethoxy]ethanol CEEE 2-[2-(2-Chloroethoxy)ethoxy]ethanol > Ethanol, 2-[2-(2-chloroethoxy)ethoxy]- 2-Chloroethoxy Ethoxy Ethanol 2-[2-(2-chloroethoxy)ethoxy]ethan-1-ol 2-Chloroethoxy-2-ethoxydiethanol 5197-62-6 C6H13ClO3 ClCH2CH2O2CH2CH2OH Monofunctional Ethylene Glycols Ethylene Glycols & Monofunctional Ethylene Glycols Organic Building Blocks Oxygen Compounds C2 to C6 Alcohols Building Blocks Aliphatics Intermediates Polyethyleneglycol Derivatives Ethylene Glycols & Monofunctional Ethylene Glycols Monofunctional Ethylene Glycols